{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T21:04:02Z","timestamp":1740171842286,"version":"3.37.3"},"reference-count":15,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,4,13]],"date-time":"2022-04-13T00:00:00Z","timestamp":1649808000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Scientific and Technological Project of Shiyan City of Hubei Province","award":["21Y46","2021ESOF017"],"award-info":[{"award-number":["21Y46","2021ESOF017"]}]},{"DOI":"10.13039\/501100014361","name":"Hubei University of Medicine","doi-asserted-by":"publisher","award":["21Y46","2021ESOF017"],"award-info":[{"award-number":["21Y46","2021ESOF017"]}],"id":[{"id":"10.13039\/501100014361","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Disease Markers"],"published-print":{"date-parts":[[2022,4,13]]},"abstract":"<jats:p>Objective. To evaluate whether there is a difference in clinical pregnancy rate and live birth rate between the corresponding period in 2019 and COVID-19 city lockdown period in 2020 in frozen embryo transfer (FET). Methods. In one single in vitro fertilization (IVF) center (Shiyan, Hubei province, China), a retrospective cohort analysis was conducted, with a sample size of 59 patients in the lockdown period (2020.1.23-2020.2.23, 2020 group) and 34 patients in the corresponding 2019 period (2019.1.23-2019.2.23, 2019 group). Implantation, biochemical and clinical pregnancy, miscarriage, and live birth rates were all measured. Results. Age, basal serum follicle-stimulating hormone (FSH), basal serum luteinizing hormone (LH), basal serum E2, and serum total T were all comparable between the two groups. On the day of progesterone administration, endometrial thickness was similar (<jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mn>8.5<\/a:mn>\n                        <a:mo>\u00b1<\/a:mo>\n                        <a:mn>1.3<\/a:mn>\n                     <\/a:math>\n                  <\/jats:inline-formula> vs. <jats:inline-formula>\n                     <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mn>8.2<\/c:mn>\n                        <c:mo>\u00b1<\/c:mo>\n                        <c:mn>1.4<\/c:mn>\n                     <\/c:math>\n                  <\/jats:inline-formula>, <jats:inline-formula>\n                     <e:math xmlns:e=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                        <e:mi>P<\/e:mi>\n                        <e:mo>=<\/e:mo>\n                        <e:mn>0.356<\/e:mn>\n                     <\/e:math>\n                  <\/jats:inline-formula>). The number of transferred blastocysts was not significantly different. The two groups had similar clinical pregnancy rate (61.8% vs. 61.0%, <jats:inline-formula>\n                     <g:math xmlns:g=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\">\n                        <g:mi>P<\/g:mi>\n                        <g:mo>&gt;<\/g:mo>\n                        <g:mn>0.05<\/g:mn>\n                     <\/g:math>\n                  <\/jats:inline-formula>) and live birth rate (47.1% vs. 49.2%, <jats:inline-formula>\n                     <i:math xmlns:i=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\">\n                        <i:mi>P<\/i:mi>\n                        <i:mo>&gt;<\/i:mo>\n                        <i:mn>0.05<\/i:mn>\n                     <\/i:math>\n                  <\/jats:inline-formula>), which did not significantly differ. Nonetheless, there was a significant difference in the cancelled cycle rate between the two groups (0% vs. 28.0%, <jats:inline-formula>\n                     <k:math xmlns:k=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\">\n                        <k:mi>P<\/k:mi>\n                        <k:mo>=<\/k:mo>\n                        <k:mn>0.043<\/k:mn>\n                     <\/k:math>\n                  <\/jats:inline-formula>). Conclusions. Lockdown period FET versus corresponding period FET outcome did not show any significant difference in terms of pregnancy rate and live birth rate between two groups of patients. Although there was no significant difference, in the 2020 group, the live birth rate was higher compared with that in the 2019 group. There was a significant difference in the rate of cancelled cycles due to the seal off control. In summary, artificial endometrial preparation is an appropriate protocol for special periods.<\/jats:p>","DOI":"10.1155\/2022\/8662279","type":"journal-article","created":{"date-parts":[[2022,4,14]],"date-time":"2022-04-14T02:50:07Z","timestamp":1649904607000},"page":"1-5","source":"Crossref","is-referenced-by-count":0,"title":["The Effects of City Lockdown Policy on Frozen Embryo Transfer Outcome during COVID-19 Epidemic in Hubei Province, China"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4316-0472","authenticated-orcid":true,"given":"Huiqi","family":"Liao","sequence":"first","affiliation":[{"name":"Reproductive Medicine Center, Renmin Hospital, Hubei University of Medicine, Shiyan 442000, China"},{"name":"Hubei Clinical Research Center for Reproductive Medicine, Shiyan 442000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5673-5247","authenticated-orcid":true,"given":"Zhifeng","family":"Sun","sequence":"additional","affiliation":[{"name":"Reproductive Medicine Center, Renmin Hospital, Hubei University of Medicine, Shiyan 442000, China"},{"name":"Hubei Clinical Research Center for Reproductive Medicine, Shiyan 442000, China"},{"name":"Biomedical Engineering College, Hubei University of Medicine, Shiyan 442000, China"},{"name":"Biomedical Research Institute, Hubei University of Medicine, Shiyan 442000, China"},{"name":"Hubei Key Laboratory of Embryonic Stem Cell Research, Shiyan 442000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30183-5"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2001017"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2001316"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc2001272"},{"issue":"1","key":"5","first-page":"1","article-title":"Artificial endometrial preparation for frozen-thawed embryo transfer with or without pretreatment with depot gonadotropin releasing hormone agonist in women with regular menses","volume":"9","author":"E. Azimi Nekoo","year":"2015","journal-title":"Journal of Family & Reproductive Health"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.humrep.a137983"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-014-3396-0"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2008.11.027"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1186\/1743-1050-5-4"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD006359.pub3"},{"issue":"4","key":"11","first-page":"718","article-title":"The effect of accompanying dominant follicle development\/ovulation on the outcomes of frozen-thawed blastocyst transfer in HRT cycle","volume":"6","author":"X. Yang","year":"2013","journal-title":"International Journal of Clinical and Experimental Pathology"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2006.05.013"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/12.6.1176"},{"issue":"5","key":"14","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1016\/S0015-0282(02)02960-6","article-title":"Endometrial preparation for frozen-thawed embryo transfer with or without pretreatment with gonadotropin-releasing hormone agonist","volume":"77","author":"L. Dal Prato","year":"2002","journal-title":"Fertility and Sterility"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1089\/whr.2021.0054"}],"container-title":["Disease Markers"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/dm\/2022\/8662279.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/dm\/2022\/8662279.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/dm\/2022\/8662279.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,14]],"date-time":"2022-04-14T02:50:14Z","timestamp":1649904614000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/dm\/2022\/8662279\/"}},"subtitle":[],"editor":[{"given":"Simin","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2022,4,13]]},"references-count":15,"alternative-id":["8662279","8662279"],"URL":"https:\/\/doi.org\/10.1155\/2022\/8662279","relation":{},"ISSN":["1875-8630","0278-0240"],"issn-type":[{"type":"electronic","value":"1875-8630"},{"type":"print","value":"0278-0240"}],"subject":[],"published":{"date-parts":[[2022,4,13]]}}}