{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T14:31:26Z","timestamp":1753885886746,"version":"3.41.2"},"reference-count":15,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T00:00:00Z","timestamp":1645401600000},"content-version":"vor","delay-in-days":51,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contrast Media &amp; Molecular Imaging"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. Solitary pulmonary intravascular metastasis is a rare complication of malignant tumors, and accurate diagnosis can improve clinical decision\u2010making, but diagnosing it effectively using conventional techniques is difficult. <jats:italic>Purpose<\/jats:italic>. To explore the value of <jats:sup>18<\/jats:sup>F\u2010FDG PET\/CT combined with lung high\u2010resolution computed tomography (HRCT) in the diagnosis of solitary pulmonary intravascular metastasis. <jats:italic>Methods<\/jats:italic>. <jats:sup>18<\/jats:sup>F\u2010FDG PET\/CT, lung HRCT, and follow\u2010up data of 18,143 cancer patients were retrospectively analyzed to select patients with pulmonary vessel involvement besides the primary tumor only. The histopathological or imaging follow\u2010up results were used as the diagnostic criteria for pulmonary intravascular metastasis. <jats:italic>Results<\/jats:italic>. A total of 13 patients with 17 pulmonary intravascular metastases were found, of which 9 patients had a single lesion and 4 had double. The SUVmax was 1.1\u20135.4 (average, 2.4\u2009\u00b1\u20091.4), and the length of hypermetabolic metastasis was 5.1\u201324.1\u2009mm (average, 10.7\u2009\u00b1\u20096.5\u2009mm). All the intravascular metastases were located in the terminal pulmonary vessels. Strip or branched pulmonary vessels enlargement with increased metabolism was the main imaging manifestation (15\/17, 88.2%), while the other 2 cases only showed strip metabolic enhancement without abnormalities in pulmonary vessels (2\/17, 11.8%). Four pulmonary intravascular metastases were confirmed by pathology, and the other 13 cases were diagnosed by imaging follow\u2010up. <jats:italic>Conclusion<\/jats:italic>. <jats:sup>18<\/jats:sup>F\u2010FDG PET\/CT combined with lung HRCT is an effective technique for the diagnosis of solitary pulmonary intravascular metastasis. High\u2010strip or branched FDG uptake in the distal pulmonary vessel accompanied by corresponding morphological changes in patients with malignant tumors can be used as a specific diagnostic indicator.<\/jats:p>","DOI":"10.1155\/2022\/8968855","type":"journal-article","created":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T22:21:56Z","timestamp":1645482116000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Value of <sup>18<\/sup>F\u2010FDG PET\/CT Combined with Lung HRCT in Diagnosis of Solitary Pulmonary Intravascular Metastasis"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6078-0852","authenticated-orcid":false,"given":"Yu","family":"Ji","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0493-7389","authenticated-orcid":false,"given":"Yaru","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8510-0275","authenticated-orcid":false,"given":"Jing Song","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9847-8189","authenticated-orcid":false,"given":"Chun Chun","family":"Shao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1934-0809","authenticated-orcid":false,"given":"Yong","family":"Cui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,2,21]]},"reference":[{"key":"e_1_2_8_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2017.07.001"},{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2013.05.008"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/71429"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197510)36:4<1473::aid-cncr2820360440>3.0.co;2-d"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(68)90044-2"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-2197.2012.06205.x"},{"key":"e_1_2_8_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.remn.2015.04.002"},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.cej.0000220641.46470.77"},{"key":"e_1_2_8_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10554-019-01553-5"},{"key":"e_1_2_8_10_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.187.3.8497633"},{"key":"e_1_2_8_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.acra.2014.02.013"},{"key":"e_1_2_8_12_2","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.20.23017"},{"key":"e_1_2_8_13_2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.06.0640"},{"key":"e_1_2_8_14_2","doi-asserted-by":"publisher","DOI":"10.3109\/00365521.2012.704936"},{"key":"e_1_2_8_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-008-0810-5"}],"container-title":["Contrast Media &amp; 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