{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T01:56:09Z","timestamp":1768874169356,"version":"3.49.0"},"reference-count":25,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,8,4]],"date-time":"2022-08-04T00:00:00Z","timestamp":1659571200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Computational and Mathematical Methods in Medicine"],"published-print":{"date-parts":[[2022,8,4]]},"abstract":"<jats:p>Objective. This study was designed to analyse the clinical efficacy of interventional therapy on lower extremity arteriosclerosis obliterans (LEASO) and prognostic factors. Methods. A total of 122 patients with LEASO diagnosed in our hospital from March 2017 to March 2019 were retrospectively analysed. Among them, 72 patients who received conservative therapy were assigned to a conservative group, and 50 patients who received interventional therapy additionally based on conservative therapy were assigned to an intervention group. The short-term (12 weeks after therapy) and long-term (3 years after therapy) clinical efficacies on the two groups were compared. Death, amputation, and vascular restenosis (<jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mtext>vascular<\/a:mtext>\n                        <a:mtext>\u2009<\/a:mtext>\n                        <a:mtext>stenosis<\/a:mtext>\n                        <a:mo>&gt;<\/a:mo>\n                        <a:mn>50<\/a:mn>\n                        <a:mi>%<\/a:mi>\n                     <\/a:math>\n                  <\/jats:inline-formula> in computed tomography reexamination) were defined as unfavourable outcomes, and Cox regression was conducted to analyze the factors influencing the prognosis of patients. The incidence of adverse events in the two groups within 3 years was compared and statistically analyzed. Additionally, the hospital stay, therapy cost, claudication distance, and ankle brachial index were compared between the two groups. Results. After therapy, the conservative group showed a notably lower total effective rate than the intervention group (<jats:inline-formula>\n                     <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mi>P<\/c:mi>\n                        <c:mo>&lt;<\/c:mo>\n                        <c:mn>0.05<\/c:mn>\n                     <\/c:math>\n                  <\/jats:inline-formula>), but the clinical efficacy after 3 years was similar between the two groups (<jats:inline-formula>\n                     <e:math xmlns:e=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                        <e:mi>P<\/e:mi>\n                        <e:mo>&gt;<\/e:mo>\n                        <e:mn>0.05<\/e:mn>\n                     <\/e:math>\n                  <\/jats:inline-formula>). Additionally, the conservative group experienced notably longer hospital stay than the intervention group (<jats:inline-formula>\n                     <g:math xmlns:g=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\">\n                        <g:mi>P<\/g:mi>\n                        <g:mo>&lt;<\/g:mo>\n                        <g:mn>0.05<\/g:mn>\n                     <\/g:math>\n                  <\/jats:inline-formula>), and cost less in treatment than the intervention group (<jats:inline-formula>\n                     <i:math xmlns:i=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\">\n                        <i:mi>P<\/i:mi>\n                        <i:mo>&lt;<\/i:mo>\n                        <i:mn>0.05<\/i:mn>\n                     <\/i:math>\n                  <\/jats:inline-formula>). However, the conservative group experienced a notably shorter claudication distance and showed a notably lower ankle brachial index than the intervention group (<jats:inline-formula>\n                     <k:math xmlns:k=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\">\n                        <k:mi>P<\/k:mi>\n                        <k:mo>&lt;<\/k:mo>\n                        <k:mn>0.05<\/k:mn>\n                     <\/k:math>\n                  <\/jats:inline-formula>). The two groups were not significantly different in mortality, amputation rate, and vascular restenosis rate (<jats:inline-formula>\n                     <m:math xmlns:m=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M7\">\n                        <m:mi>P<\/m:mi>\n                        <m:mo>&gt;<\/m:mo>\n                        <m:mn>0.05<\/m:mn>\n                     <\/m:math>\n                  <\/jats:inline-formula>). Moreover, Cox regression analysis revealed that age and conservative therapy were independent risk factors for the prognosis of patients (<jats:inline-formula>\n                     <o:math xmlns:o=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M8\">\n                        <o:mi>P<\/o:mi>\n                        <o:mo>&lt;<\/o:mo>\n                        <o:mn>0.05<\/o:mn>\n                     <\/o:math>\n                  <\/jats:inline-formula>). Conclusion. Interventional therapy can substantially improve the short-term efficacy and prognosis of patients with LEASO, but the cost is high, so the therapeutic regimen should be selected according to the patient\u2019s economic condition.<\/jats:p>","DOI":"10.1155\/2022\/9190292","type":"journal-article","created":{"date-parts":[[2022,8,5]],"date-time":"2022-08-05T02:35:09Z","timestamp":1659666909000},"page":"1-8","source":"Crossref","is-referenced-by-count":4,"title":["Clinical Efficacy of Interventional Therapy on Lower Extremity Arteriosclerosis Obliterans and Prognostic Factors"],"prefix":"10.1155","volume":"2022","author":[{"given":"Deshuang","family":"Xiao","sequence":"first","affiliation":[{"name":"General Surgery, The First People\u2019s Hospital of WenLing, No. 333, Chuanan Road, Wenling City, 317500 Zhejiang Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5860-8137","authenticated-orcid":true,"given":"Jun","family":"Song","sequence":"additional","affiliation":[{"name":"General Surgery, The First People\u2019s Hospital of WenLing, No. 333, Chuanan Road, Wenling City, 317500 Zhejiang Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hlc.2017.10.014"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehx095"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.3760\/cma.j.cn112139-20210923-00453"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1080\/08941939.2019.1690600"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.2753"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.919977"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/j.avsg.2019.09.005"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.17116\/kurort2019960415"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.17116\/kurort20219804154"},{"issue":"4","key":"10","first-page":"241","article-title":"Surgical treatment of lower extremity arteriosclerosis obliterans","volume":"48","author":"Q. H. Wu","year":"2010","journal-title":"Zhonghua Wai Ke Za Zhi"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1080\/00365513.2018.1452287"},{"issue":"13","key":"12","first-page":"1008","article-title":"Special issues in endovascular treatment of lower extremities arteriosclerosis obliterans","volume":"93","author":"H. Y. Duan","year":"2013","journal-title":"Zhonghua Yi Xue Za Zhi"},{"issue":"2","key":"13","doi-asserted-by":"crossref","first-page":"188","DOI":"10.23736\/S2724-5691.21.09031-6","article-title":"Analysis of the effect of color Doppler ultrasonography in the diagnosis of arteriosclerotic occlusive disease of lower extremities","volume":"77","author":"D. Shen","year":"2022","journal-title":"Minerva Surgery"},{"issue":"17","key":"14","first-page":"1188","article-title":"Balloon dilation alone in treatment of arteriosclerotic stenosis or occlusions of femoropopliteal arteries","volume":"45","author":"W. Li","year":"2007","journal-title":"Zhonghua Wai Ke Za Zhi"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2019.7476"},{"key":"16","first-page":"1033","article-title":"Endovascular treatment of multilevel arteriosclerosis obliterans of lower extremities","volume":"24","author":"Y. Gao","year":"2010","journal-title":"Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.17116\/hirurgia202008155"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.11817\/j.issn.1672-7347.2015.02.010"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.5114\/aoms.2018.78885"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1536\/ihj.17-592"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1177\/0003319718814351"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1016\/j.jos.2020.08.006"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/9975583"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1186\/s12872-020-01633-8"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.3760\/cma.j.issn.0529-5815.2016.08.002"}],"updated-by":[{"DOI":"10.1155\/2023\/9871829","type":"retraction","label":"Retraction","source":"retraction-watch","updated":{"date-parts":[[2023,6,28]],"date-time":"2023-06-28T00:00:00Z","timestamp":1687910400000},"record-id":"47451"},{"DOI":"10.1155\/2023\/9871829","type":"retraction","label":"Retraction","source":"publisher","updated":{"date-parts":[[2023,6,28]],"date-time":"2023-06-28T00:00:00Z","timestamp":1687910400000}}],"container-title":["Computational and Mathematical Methods in Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cmmm\/2022\/9190292.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cmmm\/2022\/9190292.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cmmm\/2022\/9190292.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,5]],"date-time":"2022-08-05T02:35:19Z","timestamp":1659666919000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/cmmm\/2022\/9190292\/"}},"subtitle":[],"editor":[{"given":"Min","family":"Tang","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2022,8,4]]},"references-count":25,"alternative-id":["9190292","9190292"],"URL":"https:\/\/doi.org\/10.1155\/2022\/9190292","relation":{"retraction":[{"id-type":"doi","id":"10.1155\/2023\/9871829","asserted-by":"object"}]},"ISSN":["1748-6718","1748-670X"],"issn-type":[{"value":"1748-6718","type":"electronic"},{"value":"1748-670X","type":"print"}],"subject":[],"published":{"date-parts":[[2022,8,4]]}}}