{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T08:06:32Z","timestamp":1767168392475,"version":"build-2238731810"},"reference-count":34,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,2,23]],"date-time":"2022-02-23T00:00:00Z","timestamp":1645574400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100017950","name":"Shanghai Municipal Health Commission","doi-asserted-by":"publisher","award":["201840164"],"award-info":[{"award-number":["201840164"]}],"id":[{"id":"10.13039\/100017950","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Shanghai Municipal Health Committee\u2019s General Project","award":["201840164"],"award-info":[{"award-number":["201840164"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Healthcare Engineering"],"published-print":{"date-parts":[[2022,2,23]]},"abstract":"<jats:p>\n                    Objectives. Believed to be a result of metabolic syndrome and unhealthy lifestyle, the incidence of nonalcoholic fatty liver disease (NAFLD) has become a serious public health problem. Among the high-income male population, metabolic syndrome and unhealthy lifestyle are particularly prominent. Therefore, we conducted a survey on 375 high-income male subjects, expecting to understand the risk factors and related factors for morbidity of NAFLD among the high-income male population being physically examined in Shanghai. Methods. A cross-sectional study was applied to 375 high-income male subjects (including 190 patients with NAFLD and 185 non-NAFLD subjects) who were examined in the special needs clinic at Huadong Hospital affiliated to Fudan University. In combination with medical history, physical examination, and laboratory test results and by use of a self-made NAFLD health questionnaire, the basic data of the research objects were collected and the obtained data were subject to a correlation analysis. Results. This study investigated 375 high-income males, and the morbidity rate of NAFLD was 50.67%. The NAFLD group was higher than the non-NAFLD group in terms of body weight, BMI, systolic blood pressure, and diastolic blood pressure (\n                    <jats:inline-formula>\n                      <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mi>P<\/a:mi>\n                        <a:mo>&lt;<\/a:mo>\n                        <a:mn>0.05<\/a:mn>\n                      <\/a:math>\n                    <\/jats:inline-formula>\n                    ). Hypertension (OR\u2009=\u20092.944), diabetes (OR\u2009=\u20097.278), and hyperuricemia (OR\u2009=\u20091.922) are the risk factors for NAFLD; compared with no metabolic diseases, one (OR\u2009=\u20091.848), two (OR\u2009=\u20092.417), and three metabolic diseases (OR\u2009=\u200914.788) are risk factors for the development of NAFLD. Compared with the non-NAFLD group, the NAFLD group had a higher level of WBC, RBC, Hb, PLT, FPG, HbA1c, ALT, AST, GGT, ALP, TP, and UA (\n                    <jats:inline-formula>\n                      <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mi>P<\/c:mi>\n                        <c:mo>&lt;<\/c:mo>\n                        <c:mn>0.05<\/c:mn>\n                      <\/c:math>\n                    <\/jats:inline-formula>\n                    ). There was a statistically significant difference in the intake of supper and staple foods between the NAFLD group and the non-NAFLD group, and the highly greasy diet was a risk factor for NAFLD (OR\u2009=\u20092.173) as opposed to the nongreasy diet. Conclusion. High-income male population is a high-risk group of NAFLD. Most of the patients with NAFLD have abnormal biochemical indicators as opposed to the healthy population and are more likely to be complicated with other chronic diseases or abnormal health status. And the occurrence of hypertension, diabetes, and hyperuricemia is the risk factor for the development of NAFLD. At the same time, the number of metabolic diseases complicated is also a risk factor for NAFLD as compared with the absence of complications with such metabolic diseases. Compared with a diet that is not greasy, the fact that high-income male NAFLD patients have a very greasy diet increases the risk of NAFLD.\n                  <\/jats:p>","DOI":"10.1155\/2022\/9331284","type":"journal-article","created":{"date-parts":[[2022,2,23]],"date-time":"2022-02-23T13:08:28Z","timestamp":1645621708000},"page":"1-10","source":"Crossref","is-referenced-by-count":5,"title":["Preliminary Study on Risk Factors for Morbidity of Nonalcoholic Fatty Liver Disease in High-Income Male Population"],"prefix":"10.1155","volume":"2022","author":[{"given":"Li","family":"Han","sequence":"first","affiliation":[{"name":"Huadong Hospital Affiliated to Fudan University, Department of Traditional Chinese Medicine, 221 Yan\u2019an West Road,Jing\u2019an District, Shanghai 200040, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuting","family":"Zhang","sequence":"additional","affiliation":[{"name":"Huadong Hospital Affiliated to Fudan University, Department of Digestion, 221 Yan\u2019an West Road,Jing\u2019an District, Shanghai 200040, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cui","family":"Yue","sequence":"additional","affiliation":[{"name":"The Office of Good Clinical Practice, 221 West Yan\u2019an Road, Huadong Hospital, Shanghai 200040, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yiqin","family":"Huang","sequence":"additional","affiliation":[{"name":"Huadong Hospital Affiliated to Fudan University, Department of Digestion, 221 Yan\u2019an West Road,Jing\u2019an District, Shanghai 200040, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yumin","family":"Wu","sequence":"additional","affiliation":[{"name":"Huadong Hospital Affiliated to Fudan University, Department of Nephrology, 221 Yan\u2019an West Road,Jing\u2019an District, Shanghai 200040, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2691-6677","authenticated-orcid":true,"given":"Jie","family":"Chen","sequence":"additional","affiliation":[{"name":"Huadong Hospital Affiliated to Fudan University, Department of Geriatrics, 317 Room,168 Yan\u2019an West Road,Jing\u2019an District, Shanghai 200040, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.22603"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.27406"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1002\/hep.28431"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.foot.2021.101847"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v21.i18.5695"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2016.12.006"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(18)30357-7"},{"key":"8","author":"N. 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