{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T02:02:10Z","timestamp":1775181730915,"version":"3.50.1"},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,10,5]],"date-time":"2022-10-05T00:00:00Z","timestamp":1664928000000},"content-version":"vor","delay-in-days":277,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:p><jats:italic>Purpose.<\/jats:italic> Cervical radiculopathy is disorder of cervical spinal nerve root affecting large number of population. Previously many studies are conducted to design suitable protocol for management of this disorder, but they lack in quality. The purpose of this study was to compare the effects of neural mobilization and cervical isometrics on health\u2010related quality of life and deep flexors endurance in cervical radiculopathy. <jats:italic>Methods.<\/jats:italic> A double\u2010blinded randomized clinical trial was conducted at Mayo Hospital, Lahore, Pakistan. Eighty\u2010eight patients within the age range of 35\u201050 years were included in the study after taking their consent. In the experimental group (<jats:italic>n<\/jats:italic> = 44), median nerve mobilization was applied along with cervical isometric exercises. The control group (<jats:italic>n<\/jats:italic> = 44) performed cervical isometric exercises alone. Muscle endurance was measured by craniocervical flexion test and quality of life on 36 items short form health survey SF\u201036 scale. Measurements were taken at baseline, at 2<jats:sup>nd<\/jats:sup> week, and at 4<jats:sup>th<\/jats:sup> week. For missing data, intention\u2010to\u2010treat analysis was used. <jats:italic>Results.<\/jats:italic> Within\u2010group comparison with Friedman test showed a significant difference between pre, mid, and posttreatment scores on craniocervical flexion test and in all domains of SF 36 in both groups. While between\u2010group comparison with Mann\u2013Whitney <jats:italic>U<\/jats:italic> test showed all variables were similar at baseline but after 4 weeks there was a statistically significant improvement in craniocervical flexion test scores and all domains of SF 36 in the experimental group. But domain of pain showed mean rank of 49.43 after 4 weeks in the experimental group and 39.57 in the control group with <jats:italic>p<\/jats:italic> = 0.065 and <jats:italic>d<\/jats:italic> = 0.579, while for all the other 7 domains values were <jats:italic>p<\/jats:italic> &lt; .05 and <jats:italic>d<\/jats:italic> &gt; 0.25. <jats:italic>Conclusion.<\/jats:italic> Neural mobilization combined with cervical isometrics shows significant effects in improving quality of life and deep flexors endurance in patients with cervical radiculopathy than cervical isometrics alone.<\/jats:p>","DOI":"10.1155\/2022\/9385459","type":"journal-article","created":{"date-parts":[[2022,10,5]],"date-time":"2022-10-05T22:35:06Z","timestamp":1665009306000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Effects of Neurodynamic Mobilization on Health\u2010Related Quality of Life and Cervical Deep Flexors Endurance in Patients of Cervical Radiculopathy: A Randomized Trial"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8589-4140","authenticated-orcid":false,"given":"Shazia","family":"Rafiq","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9318-3691","authenticated-orcid":false,"given":"Hamayun","family":"Zafar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2996-0764","authenticated-orcid":false,"given":"Syed Amir","family":"Gillani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad Sharif","family":"Waqas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2057-3653","authenticated-orcid":false,"given":"Sidrah","family":"Liaqat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9825-5938","authenticated-orcid":false,"given":"Amna","family":"Zia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasir","family":"Rafiq","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,10,5]]},"reference":[{"key":"e_1_2_12_1_2","doi-asserted-by":"publisher","DOI":"10.1179\/2042618611Y.0000000011"},{"key":"e_1_2_12_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11420-011-9218-z"},{"key":"e_1_2_12_3_2","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/9936981"},{"key":"e_1_2_12_4_2","article-title":"Comparison between nerve mobilization and conventional physiotherapy in patients with cervical radiculopathy","volume":"2","author":"Sambyal S.","year":"2013","journal-title":"International Journal of Innovative Research and Development"},{"key":"e_1_2_12_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12178-016-9349-4"},{"key":"e_1_2_12_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-200301010-00014"},{"key":"e_1_2_12_7_2","doi-asserted-by":"publisher","DOI":"10.3233\/BMR-140191"},{"key":"e_1_2_12_8_2","unstructured":"ButlerD. 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