{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T07:26:38Z","timestamp":1767165998971,"version":"build-2238731810"},"reference-count":32,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,11,17]],"date-time":"2022-11-17T00:00:00Z","timestamp":1668643200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Evidence-Based Complementary and Alternative Medicine"],"published-print":{"date-parts":[[2022,11,17]]},"abstract":"<jats:p>\n                    Objective. The purpose of this study is to assess the efficacy and safety of the integration of Western medicine with traditional Chinese medicine (TCM) in patients with coronary heart disease (CHD) which is comorbid with anxiety and depression. Methods. Randomized controlled trials (RCTs) were searched in databases such as VIP, WanFang, CNKI, Embase, PubMed, and Cochrane Library from the inception of databases to November 2021. RCTs on treating CHD comorbid with anxiety and depression with the integration of TCM and Western medicine were retrieved, and publications were screened according to the screening criteria. Software RevMan 5.4 was utilized to analyze related indicators. Results. Thirteen eligible studies were included in this meta-analysis. They involved a total of 1460 cases, including 747 cases in the TCM and Western medicine group, and 713 cases in the control group. Meta-analysis results illustrated that the difference in the relief of angina pectoris in treating CHD comorbid with anxiety and depression with the integration of TCM and Western medicine was statistically significant (OR\u2009=\u20093.97, 95% CI [2.47, 6.39],\n                    <jats:inline-formula>\n                      <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mi>P<\/a:mi>\n                        <a:mo>&lt;<\/a:mo>\n                        <a:mn>0.05<\/a:mn>\n                      <\/a:math>\n                    <\/jats:inline-formula>\n                    ), and HAMD score, HAMA score, and clinical effective rate were statistically significant (MD\u2009=\u2009\u22124.11, 95% CI [\u22125.10, 3.12]), (SMD\u2009=\u20091.88, 95% CI [2.53, 1.24]), (OR\u2009=\u20099.71, 95% CI [4.65, 20.28]). Conclusion. By combining TCM and Western medicine, the treatment of angina pectoris and CHD comorbid with anxiety and depression can alleviate anxiety and depression and can enhance patients\u2019 quality of life.\n                  <\/jats:p>","DOI":"10.1155\/2022\/9586456","type":"journal-article","created":{"date-parts":[[2022,11,17]],"date-time":"2022-11-17T18:05:05Z","timestamp":1668708305000},"page":"1-9","source":"Crossref","is-referenced-by-count":1,"title":["Efficacy of the Integration of Traditional Chinese Medicine and Western Medicine in Coronary Heart Disease Comorbid with Anxiety and Depression: A Meta-Analysis"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9707-3737","authenticated-orcid":true,"given":"Yiyuan","family":"Sun","sequence":"first","affiliation":[{"name":"Department of Oncology Medicine, Shanghai Pudong Gongli Hospital, Shanghai 200135, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4768-6375","authenticated-orcid":true,"given":"Chi","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Shanghai International Medical Center, Shanghai 201315, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3890-8810","authenticated-orcid":true,"given":"Shaoyi","family":"Qu","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Shanghai Pudong Gongli Hospital, Shanghai 200135, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9523-6520","authenticated-orcid":true,"given":"Bohui","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Oncology Medicine, Shanghai Pudong Gongli Hospital, Shanghai 200135, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","volume-title":"Coronary Heart Disease","author":"E. D. Angelantonio","year":"2011"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)91846-m"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2016.2050"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1080\/07315724.2017.1381053"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1038\/nrcardio.2016.181"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1111\/nyas.12738"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2018.11.017"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpr.2007.05.005"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1136\/ebnurs-2018-103012"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1177\/2047487317721021"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1097\/psy.0b013e318291d798"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0187016"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.d5928"},{"issue":"6","key":"14","first-page":"51","article-title":"Efficacy of Danzhi Xiaoyao San on 58 cases with coronary heart disease with angina pectoris and mild to moderate depression","volume":"31","author":"Y. Bao","year":"2016","journal-title":"Forum On Traditional Chinese Medicine"},{"issue":"15","key":"15","first-page":"1671","article-title":"Seventy-five coronary heart disease cases with depression treated with the integration of traditional Chinese and Western medicine","volume":"23","author":"Q. Dong","year":"2014","journal-title":"Modern Journal of Integrated Traditional Chinese and Western Medicine"},{"issue":"12","key":"16","first-page":"118","article-title":"Clinical observation on 40 cases of angina pectoris complicated with anxiety and depression treated with the integration of traditional Chinese and Western medicine","volume":"27","author":"C. Li","year":"2018","journal-title":"Chinese Journal of Ethnomedicine and Ethnopharmacy"},{"issue":"18","key":"17","first-page":"79","article-title":"Clinical observation on 30 cases of coronary heart disease with depression treated with the integration of traditional Chinese and Western medicine","volume":"27","author":"L. Li","year":"2018","journal-title":"Chinese Journal of Ethnomedicine and Ethnopharmacy"},{"issue":"7","key":"18","first-page":"890","article-title":"Analysis of the efficacy of the integration of traditional Chinese and Western medicine in coronary heart disease comorbid with depression and anxiety","volume":"8","author":"M. Liu","year":"2013","journal-title":"China Medicine"},{"issue":"3","key":"19","first-page":"45","article-title":"A randomized parallel controlled study of Chaihu Shugan powder combined with Western medicine in the treatment of depressive coronary heart disease","volume":"28","author":"Y. Liu","year":"2014","journal-title":"Journal of Practical Traditional Chinese Internal Medicine"},{"issue":"15","key":"20","first-page":"124","article-title":"Clinical observation on 46 cases of coronary heart disease complicated with anxiety and depression treated with the integration of traditional Chinese and Western medicine","volume":"27","author":"N. Lu","year":"2018","journal-title":"Chinese Journal of Ethnomedicine and Ethnopharmacy"},{"issue":"16","key":"21","first-page":"229","article-title":"Observation on the curative effect of combined traditional Chinese and Western medicine on patients with coronary heart disease complicated with anxiety and depression","volume":"1","author":"X. Peng","year":"2017","journal-title":"Journal of Imaging Research and Medical Applications"},{"issue":"4","key":"22","article-title":"Clinical treatment of patients with coronary heart disease comorbid with depression and anxiety","volume":"26","author":"W. Tan","year":"2015","journal-title":"Modern Diagnosis & Treatment"},{"issue":"19","key":"23","first-page":"34","article-title":"Clinical observation of the integration of Chinese traditional and Western medicine in the treatment of coronary artery disease and anxiety with depression","volume":"16","author":"J. Tao","year":"2013","journal-title":"Chinese Journal of Practical Nervous Diseases"},{"issue":"8","key":"24","first-page":"1178","article-title":"Forty cases of angina due to coronary atherosclerotic heart disease combined with depressive disorder treated with bupleurum liver-soothing powder in combination with isosorbide mononitrate tablets","volume":"38","author":"L. Wang","year":"2018","journal-title":"Henan Traditional Chinese Medicine"},{"issue":"10","key":"25","first-page":"23","article-title":"Clinical observation of the integration of traditional Chinese and Western medicine on coronary heart disease with depression and anxiety","volume":"33","author":"L. Zhang","year":"2017","journal-title":"Shanxi Journal of Traditional Chinese Medicine"},{"key":"26","first-page":"61","article-title":"Sixty cases of coronary heart disease with depression treated with xiaoyao powder combined with fluoxetine Chinese medicine modern distance education of China","author":"Y. Zong","year":"2015"},{"issue":"11","key":"27","first-page":"1305","article-title":"To observe the clinical effect of relieving depression and activating blood circulation on patients with angina pectoris of coronary heart disease with anxiety and depression","volume":"19","author":"Z. Lc","year":"2013","journal-title":"Chinese Journal of Basic Medicine in Traditional Chinese Medicine"},{"issue":"65","key":"28","article-title":"Progress in TCM treatment of coronary heart disease complicated with anxiety and depression","volume":"15","author":"S. Yueyuan","year":"2015","journal-title":"World Latest Medicine Information"},{"issue":"1","key":"29","first-page":"31","article-title":"Coronary depression and abnormal emotion caused by collateral dysfunction","volume":"21","author":"J. P. Z. Yuanzhuo","year":"2007","journal-title":"Academic Journal of Shanghai University of Traditional Chinese Medicine"},{"issue":"15","key":"30","first-page":"1312","article-title":"TCM syndrome Characteristics of coronary heart disease complicated by depression","volume":"53","author":"L. F. W. J. Zhang","year":"2012","journal-title":"Journal of Traditional Chinese Medicine"},{"issue":"05","key":"31","first-page":"231","article-title":"Efficacy of Yishen Huoxue Shugan decoction in treating coronary heart disease complicated with depression","volume":"9","author":"J. Li","year":"2015","journal-title":"Chinese Journal of Modern Drug Application"},{"key":"32","volume-title":"Effect of Jieyu Qingxin Ningshenfang on Quality of Life in Patients with Stable Angina Pectoris, and Anxiety and Depression","author":"L. Zhen","year":"2019"}],"updated-by":[{"DOI":"10.1155\/2023\/9852605","type":"retraction","label":"Retraction","source":"retraction-watch","updated":{"date-parts":[[2023,12,13]],"date-time":"2023-12-13T00:00:00Z","timestamp":1702425600000},"record-id":"59378"},{"DOI":"10.1155\/2023\/9852605","type":"retraction","label":"Retraction","source":"publisher","updated":{"date-parts":[[2023,12,13]],"date-time":"2023-12-13T00:00:00Z","timestamp":1702425600000}}],"container-title":["Evidence-Based Complementary and Alternative Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/ecam\/2022\/9586456.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ecam\/2022\/9586456.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ecam\/2022\/9586456.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,17]],"date-time":"2022-11-17T18:05:20Z","timestamp":1668708320000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/ecam\/2022\/9586456\/"}},"subtitle":[],"editor":[{"given":"Muhammad","family":"Zia-Ul-Haq","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2022,11,17]]},"references-count":32,"alternative-id":["9586456","9586456"],"URL":"https:\/\/doi.org\/10.1155\/2022\/9586456","relation":{},"ISSN":["1741-4288","1741-427X"],"issn-type":[{"value":"1741-4288","type":"electronic"},{"value":"1741-427X","type":"print"}],"subject":[],"published":{"date-parts":[[2022,11,17]]}}}