{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T08:15:20Z","timestamp":1767168920924,"version":"build-2238731810"},"reference-count":23,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,6,11]],"date-time":"2022-06-11T00:00:00Z","timestamp":1654905600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Oncology"],"published-print":{"date-parts":[[2022,6,11]]},"abstract":"<jats:p>Colorectal cancer is one of the leading causes of deaths in China. The initial stages of colorectal cancer can be treated by surgery, radiation, and chemotherapy. However, in the advanced stages, it warrants an application of multimodality treatment. With advances in the medical field, there are applications of new modality of treatment that could possibly provide the appropriate treatment for the advanced stage tumours. The first site of metastasis after colorectal cancer is the liver and the conventional treatment to cure the metastatic lesion involves the administration of chemotherapy. With further advancement, chemotherapy has been directly administered at the thorough transarterial chemoembolization (TACE) which is a vascular intervention. With further advancement, the nonvascular intervention, such as radiofrequency ablations (RFAs), has been administered to the patients. A large amount of data support the use of vascular intervention (TACE) with ablation for hepatic carcinoma; there is no sufficient literature to support the application of the modality in the metastatic liver lesion. In this prospective observational study, we have enrolled 80 patients with metastatic liver lesion from the adenocarcinoma of colon or rectum, treated the patients with a combination of the TACE and ablation therapy, and followed up the patients for a period of 3 years. A multivariate analysis of the various factors that influence the prognosis and outcome has been studied and it has been concluded that the combination therapy is medically beneficial for individuals with aggressive liver lesions, improving overall as well as progression-free life span.<\/jats:p>","DOI":"10.1155\/2022\/9690401","type":"journal-article","created":{"date-parts":[[2022,6,11]],"date-time":"2022-06-11T15:50:07Z","timestamp":1654962607000},"page":"1-9","source":"Crossref","is-referenced-by-count":2,"title":["Multifactorial Analysis of Clinical Prognosis of Liver Metastasis and Vascular Intervention Combined with Ablation in Colorectal Cancer"],"prefix":"10.1155","volume":"2022","author":[{"given":"WenJi","family":"Lin","sequence":"first","affiliation":[{"name":"Department of Interventional, Quanzhou First Hospital Affiliated of Fujian Medical University, Quanzhou 362000, Fujian, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"CongHui","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Interventional, Quanzhou First Hospital Affiliated of Fujian Medical University, Quanzhou 362000, Fujian, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JiaDi","family":"Yao","sequence":"additional","affiliation":[{"name":"Department of Interventional, Quanzhou First Hospital Affiliated of Fujian Medical University, Quanzhou 362000, Fujian, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"YuHuang","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Interventional, Quanzhou First Hospital Affiliated of Fujian Medical University, Quanzhou 362000, Fujian, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"HuiYu","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Imaging, Quanzhou First Hospital Affiliated of Fujian Medical University, Quanzhou 362000, Fujian, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2127-0758","authenticated-orcid":true,"given":"Yan","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery, Quanzhou First Hospital Affiliated of Fujian Medical University, Quanzhou 362000, Fujian, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30925-9\/ATTACHMENT\/96EE692B-E8A2-4D2B-AB04-5A9B1490A107\/MMC2E"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1186\/S40880-019-0368-6"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1097\/CM9.0000000000001474"},{"issue":"4","key":"4","doi-asserted-by":"crossref","first-page":"257","DOI":"10.17816\/brmma65173","article-title":"Radiation-induced oral mucositis\u2014radiation-induced oral mucositis: pathogenesis, risk factors, clinical manifestations, prevention, and treatment","volume":"23","author":"V. I. Legeza","year":"2021","journal-title":"Bulletin of the Russian Military Medical Academy"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.6004\/JNCCN.2015.0087"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1093\/ANNONC\/MDW235"},{"issue":"3","key":"7","first-page":"755","article-title":"Short-term assessment of the safety and efficacy of laparoscopic versus open abdominoperineal resection for treatment of low rectal cancer: a prospective randomized trial","volume":"40","author":"M. Elrefai","year":"2021","journal-title":"The Egyptian Journal of Surgery"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1186\/s12957-015-0758-4"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.18632\/ONCOTARGET.8630"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1007\/S00432-018-2795-1\/FIGURES\/6"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1007\/S00268-015-3386-9"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvir.2021.05.032"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1002\/CNCR.29534"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.25259\/AJIR-21-2018"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2012.42.9936"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.3748\/WJG.V20.I15.4115"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1055\/S-0030-1247132"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1097\/MEG.0B013E32835D2C4F"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.923263"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2016.66.6198"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2020.03.011"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1016\/j.annonc.2021.08.1752"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.3748\/WJG.V23.I48.8582"}],"updated-by":[{"DOI":"10.1155\/2023\/9816834","type":"retraction","label":"Retraction","source":"retraction-watch","updated":{"date-parts":[[2023,8,2]],"date-time":"2023-08-02T00:00:00Z","timestamp":1690934400000},"record-id":"55201"},{"DOI":"10.1155\/2023\/9816834","type":"retraction","label":"Retraction","source":"publisher","updated":{"date-parts":[[2023,8,2]],"date-time":"2023-08-02T00:00:00Z","timestamp":1690934400000}}],"container-title":["Journal of Oncology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/jo\/2022\/9690401.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/jo\/2022\/9690401.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/jo\/2022\/9690401.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,11]],"date-time":"2022-06-11T15:50:19Z","timestamp":1654962619000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/jo\/2022\/9690401\/"}},"subtitle":[],"editor":[{"given":"Ashok","family":"Pandurangan","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2022,6,11]]},"references-count":23,"alternative-id":["9690401","9690401"],"URL":"https:\/\/doi.org\/10.1155\/2022\/9690401","relation":{},"ISSN":["1687-8469","1687-8450"],"issn-type":[{"value":"1687-8469","type":"electronic"},{"value":"1687-8450","type":"print"}],"subject":[],"published":{"date-parts":[[2022,6,11]]}}}