{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T15:45:16Z","timestamp":1792079116005,"version":"4.4.0"},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,4,6]],"date-time":"2022-04-06T00:00:00Z","timestamp":1649203200000},"content-version":"vor","delay-in-days":95,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Dentistry"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:p>\n                    <jats:italic>Objective<\/jats:italic>\n                    . To determine the correlation between consanguineous marriages and dental anomalies.\n                    <jats:italic>Study Design<\/jats:italic>\n                    . A cross\u2010sectional analytical study.\n                    <jats:italic>Materials and Methods<\/jats:italic>\n                    . This cross\u2010sectional analytical multicentered study was carried out at Foundation University College of Dentistry after approval of the Ethical Research Committee (ERC) from September 2021 to November 2021 in Pakistan. All pediatric patients (4\u201310 years old) with dental malformations undergoing dental procedures or examinations and born with spontaneous vaginal delivery and uncomplicated cesarean section participated in the study. First, second, and third\u2010degree relatives\u2019 marriages of parents were used to define consanguinity. The Basic Pay Scale was the reference of estimation of socioeconomic status. Participants with a history of orofacial trauma, pertinent parental history (infertility, hormonal treatment, or infectious diseases during pregnancy, conception with assisted reproductive techniques, prolonged complicated labor, premature deliveries, and twin births), and prolonged hospital admission immediately after birth were excluded from the study.\n                    <jats:italic>Results<\/jats:italic>\n                    . The mean maternal and paternal age was recorded to be 23.86\u2009\u00b1\u20095.4 and 27.07\u2009\u00b1\u20099.6, respectively, whereas the mean age of participants was 6.60\u2009\u00b1\u20091.67. There were 297 children with congenital abnormalities, with 203 (68.4%) males and 94 (31.6%) females. The prevalence of consanguineous marriage was found to be in 210 (70.7%) participants. Congenital dental anomalies correlation was found to be significant with consanguineous marriages (\n                    <jats:italic>p<\/jats:italic>\n                    value &lt;0.001). Consanguineous marriages were more frequent in the lower socioeconomic group when compared with the middle and upper socioeconomic groups, respectively (74.7% vs. 8.1% vs. 17.2%,\n                    <jats:italic>p<\/jats:italic>\n                    value 0.007).\n                    <jats:italic>Conclusion<\/jats:italic>\n                    . Congenital dental anomalies were significantly prevalent in consanguineous marriages with greater incidence in lower socioeconomic groups. Consanguineous marriages have the propensity to transmute population conformation, but due to religious and social beliefs, literature is hesitant to ascribe congenital dental anomalies persuasive relevance with consanguinity.\n                  <\/jats:p>","DOI":"10.1155\/2022\/9750460","type":"journal-article","created":{"date-parts":[[2022,4,6]],"date-time":"2022-04-06T20:50:09Z","timestamp":1649278209000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Consanguineous Marriages and Dental Anomalies: A Cross\u2010Sectional Analytical Study"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8956-5603","authenticated-orcid":false,"given":"Beenish","family":"Abbas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sana","family":"Abbas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saadia Muneer","family":"Malik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Majida","family":"Rahim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Umair","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7998-7335","authenticated-orcid":false,"given":"Zohaib","family":"Khurshid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,4,6]]},"reference":[{"key":"e_1_2_8_1_2","doi-asserted-by":"publisher","DOI":"10.1111\/ahg.12308"},{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.1515\/jpem-2017-0188"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1017\/s002193202000022x"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12687-019-00433-8"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2018.10.042"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.1080\/03014460.2016.1265148"},{"key":"e_1_2_8_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11920-019-1124-y"},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0241610"},{"key":"e_1_2_8_9_2","doi-asserted-by":"publisher","DOI":"10.4054\/demres.2014.30.9"},{"key":"e_1_2_8_10_2","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2008.070520"},{"key":"e_1_2_8_11_2","doi-asserted-by":"publisher","DOI":"10.3390\/jimaging7110238"},{"key":"e_1_2_8_12_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12903-017-0352-y"},{"key":"e_1_2_8_13_2","doi-asserted-by":"publisher","DOI":"10.18203\/2320-1770.ijrcog20181898"},{"key":"e_1_2_8_14_2","article-title":"Dental anomalies in consanguineous marriage: a clinical-radiological study","volume":"72","author":"Ba\u011fc\u0131 N.","year":"2021","journal-title":"International Dental Journal"},{"key":"e_1_2_8_15_2","doi-asserted-by":"publisher","DOI":"10.5005\/jp-journals-10005-1567"},{"key":"e_1_2_8_16_2","doi-asserted-by":"publisher","DOI":"10.4103\/njcp.njcp_615_18"},{"key":"e_1_2_8_17_2","doi-asserted-by":"publisher","DOI":"10.5368\/aedj.2010.2.4.199-203.pdf"},{"key":"e_1_2_8_18_2","first-page":"732","article-title":"Consanguinity-related hyperdontia: an orthopantomographic study","volume":"10","author":"Shokry S. M.","year":"2013","journal-title":"Dental Research Journal"},{"key":"e_1_2_8_19_2","doi-asserted-by":"publisher","DOI":"10.5772\/intechopen.68801"},{"key":"e_1_2_8_20_2","first-page":"629","article-title":"Prevalence and pattern of congenital malformations among neonates in the neonatal unit of a teaching hospital","volume":"64","author":"Hussain S.","year":"2014","journal-title":"The Journal of the Pakistan Medical Association"},{"key":"e_1_2_8_21_2","first-page":"340","article-title":"Frequency and pattern of distribution of congenital anomalies in the newborn and associated maternal risk factors","volume":"17","author":"Perveen F.","year":"2007","journal-title":"Journal of the College of Physicians and Surgeons-Pakistan: JCPSP"}],"container-title":["International Journal of Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2022\/9750460","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/2022\/9750460","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2022\/9750460","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T14:59:56Z","timestamp":1792076396000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2022\/9750460"}},"subtitle":[],"editor":[{"given":"Luca","family":"Testarelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["10.1155\/2022\/9750460"],"URL":"https:\/\/doi.org\/10.1155\/2022\/9750460","archive":["Portico"],"relation":{},"ISSN":["1687-8728","1687-8736"],"issn-type":[{"value":"1687-8728","type":"print"},{"value":"1687-8736","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1]]},"assertion":[{"value":"2021-11-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"9750460"}}