{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T21:55:11Z","timestamp":1776462911757,"version":"3.51.2"},"reference-count":21,"publisher":"Wiley","license":[{"start":{"date-parts":[[2023,1,7]],"date-time":"2023-01-07T00:00:00Z","timestamp":1673049600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Dentistry"],"published-print":{"date-parts":[[2023,1,7]]},"abstract":"<jats:p>Objective. Individuals with syndromic craniosynostosis present alterations in the dental arches due to anomalies caused by the early fusion of the craniomaxillary sutures. This study aimed to compare intradental and interdental dimensions between individuals with Apert and Crouzon syndromes and nonsyndromic controls. Materials and Methods. Digital models were obtained from the archive of a public tertiary care hospital. The sample consisted of 34 patients (Apert n\u2009=\u200918, Crouzon n\u2009=\u200916) and 34 nonsyndromic controls matched for gender and age. Measurements of perimeter, length, intercanine and intermolar distances (upper and lower), overjet, and molar ratio were performed. Statistical comparisons were performed using ANOVA and Tukey tests <jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mfenced open=\"(\" close=\")\" separators=\"|\">\n                           <a:mrow>\n                              <a:mi>p<\/a:mi>\n                              <a:mo>&lt;<\/a:mo>\n                              <a:mn>0.05<\/a:mn>\n                           <\/a:mrow>\n                        <\/a:mfenced>\n                     <\/a:math>\n                  <\/jats:inline-formula>. Results. Patients with Apert and Crouzon syndromes have severely reduced maxillary transverse dimensions, perimeter, and length of the upper arch compared to the control group <jats:inline-formula>\n                     <f:math xmlns:f=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <f:mfenced open=\"(\" close=\")\" separators=\"|\">\n                           <f:mrow>\n                              <f:mi>p<\/f:mi>\n                              <f:mo>&lt;<\/f:mo>\n                              <f:mn>0.001<\/f:mn>\n                           <\/f:mrow>\n                        <\/f:mfenced>\n                     <\/f:math>\n                  <\/jats:inline-formula>. The lower arch is less impacted. Patients with Apert syndrome had an anterior crossbite <jats:inline-formula>\n                     <k:math xmlns:k=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                        <k:mfenced open=\"(\" close=\")\" separators=\"|\">\n                           <k:mrow>\n                              <k:mi>p<\/k:mi>\n                              <k:mo>&lt;<\/k:mo>\n                              <k:mn>0.001<\/k:mn>\n                           <\/k:mrow>\n                        <\/k:mfenced>\n                     <\/k:math>\n                  <\/jats:inline-formula>, while patients with Crouzon syndrome had an edge-to-edge bite <jats:inline-formula>\n                     <p:math xmlns:p=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\">\n                        <p:mfenced open=\"(\" close=\")\" separators=\"|\">\n                           <p:mrow>\n                              <p:mi>p<\/p:mi>\n                              <p:mo>&lt;<\/p:mo>\n                              <p:mtext>\u2009<\/p:mtext>\n                              <p:mn>0.011<\/p:mn>\n                           <\/p:mrow>\n                        <\/p:mfenced>\n                     <\/p:math>\n                  <\/jats:inline-formula>. Patients with Apert and Crouzon syndromes do not have serious transverse proportion problems when comparing the upper and lower arches. Conclusions. In this sample, both the Apert and Crouzon groups have severely compromised upper arches compared to the control group. Mild dentoalveolar expansion in the maxilla should be sufficient for the transverse adaptation of the dental arches before frontofacial advancement.<\/jats:p>","DOI":"10.1155\/2023\/1043369","type":"journal-article","created":{"date-parts":[[2023,1,7]],"date-time":"2023-01-07T20:05:05Z","timestamp":1673121905000},"page":"1-8","source":"Crossref","is-referenced-by-count":5,"title":["Three-Dimensional Evaluation of Dental Arches in Individuals with Syndromic Craniosynostosis"],"prefix":"10.1155","volume":"2023","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3966-9727","authenticated-orcid":true,"given":"Rayane de Oliveira","family":"Pinto","sequence":"first","affiliation":[{"name":"Department of Orthodontics, S\u00e3o Paulo State University (UNESP), School of Dentistry, Araraquara, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0881-416X","authenticated-orcid":true,"given":"Cristiano","family":"Tonello","sequence":"additional","affiliation":[{"name":"Craniofacial Department, Hospital for Rehabilitation of Craniofacial Anomalies, University of S\u00e3o Paulo, Bauru, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4414-6111","authenticated-orcid":true,"given":"Adriano Porto","family":"Peixoto","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, Hospital for Rehabilitation of Craniofacial Anomalies, University of S\u00e3o Paulo, Bauru, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2889-112X","authenticated-orcid":true,"given":"Adriana Souza","family":"de Jesus","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, S\u00e3o Paulo State University (UNESP), School of Dentistry, Araraquara, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3355-0001","authenticated-orcid":true,"given":"Ary dos","family":"Santos-Pinto","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, S\u00e3o Paulo State University (UNESP), School of Dentistry, Araraquara, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0409-3481","authenticated-orcid":true,"given":"Dirceu Barnab\u00e9","family":"Raveli","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, S\u00e3o Paulo State University (UNESP), School of Dentistry, Araraquara, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/0895-4356(90)90058-w"},{"issue":"2","key":"2","first-page":"321","article-title":"Analysis of phenotypic features and FGFR2 mutations in apert syndrome","volume":"57","author":"W. 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