{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T15:59:16Z","timestamp":1776355156488,"version":"3.51.2"},"reference-count":39,"publisher":"Wiley","license":[{"start":{"date-parts":[[2023,12,13]],"date-time":"2023-12-13T00:00:00Z","timestamp":1702425600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Natural Science Foundation for Young Scientists of Xinjiang Uygur Autonomous Region","award":["2020D01C130"],"award-info":[{"award-number":["2020D01C130"]}]},{"name":"Natural Science Foundation for Young Scientists of Xinjiang Uygur Autonomous Region","award":["81860148"],"award-info":[{"award-number":["81860148"]}]},{"name":"Natural Science Foundation for Young Scientists of Xinjiang Uygur Autonomous Region","award":["20190105"],"award-info":[{"award-number":["20190105"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["2020D01C130"],"award-info":[{"award-number":["2020D01C130"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81860148"],"award-info":[{"award-number":["81860148"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["20190105"],"award-info":[{"award-number":["20190105"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Project in the People\u2019s Hospital of Xinjiang Uygur Autonomous Region","award":["2020D01C130"],"award-info":[{"award-number":["2020D01C130"]}]},{"name":"Project in the People\u2019s Hospital of Xinjiang Uygur Autonomous Region","award":["81860148"],"award-info":[{"award-number":["81860148"]}]},{"name":"Project in the People\u2019s Hospital of Xinjiang Uygur Autonomous Region","award":["20190105"],"award-info":[{"award-number":["20190105"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Endocrinology"],"published-print":{"date-parts":[[2023,12,13]]},"abstract":"<jats:p>Purpose. Women with Hashimoto\u2019s thyroiditis (HT) have an increased risk of ovarian insufficiency. However, whether thyroid antibodies affect the ovarian reserve remains controversial. The aim of this study was to explore the possible relationship between anti-M\u00fcllerian hormone (AMH) and thyroid peroxidase antibody (TPOAb) and thyroglobulin antibody (TgAb) levels in women of reproductive age. Methods. A total of 483 women between 18 and 45\u2009years old who had their TPOAb, TgAb, thyroid-stimulating hormone (TSH), free thyroxine (FT4), and AMH levels measured on the same day were enrolled in this study. The levels of TSH, FT4, TPOAb, and TgAb, the prevalence of overt and subclinical hypothyroidism, and the positive rate of TPOAb and TgAb were compared between patients with low (below the 10th percentile), normal (10th to 90th percentile), and high (higher than the 90th percentile) AMH levels. Results. The median AMH level was 1.72 (0.33\u20134.27) ng\/mL. A total of 9.9% of patients had low AMH levels. The TgAb levels and the prevalence of TgAb positivity were higher in the low AMH group (37.62 (13.10\u2013232.68) IU\/mL, 35.42%) than in the normal (12.46 (10.0\u201367.04) IU\/mL, 19.59%) and high (13.61 (10.0\u201395.74) IU\/mL, 23.4%) AMH groups (<jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mi>p<\/a:mi>\n                        <a:mo>=<\/a:mo>\n                        <a:mn>0.001<\/a:mn>\n                     <\/a:math>\n                  <\/jats:inline-formula>, <jats:inline-formula>\n                     <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mi>p<\/c:mi>\n                        <c:mo>=<\/c:mo>\n                        <c:mn>0.040<\/c:mn>\n                     <\/c:math>\n                  <\/jats:inline-formula>, respectively). Serum AMH levels were inversely correlated with TgAb levels (r\u2009=\u2009\u22120.114, <jats:inline-formula>\n                     <e:math xmlns:e=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                        <e:mi>p<\/e:mi>\n                        <e:mo>=<\/e:mo>\n                        <e:mn>0.013<\/e:mn>\n                     <\/e:math>\n                  <\/jats:inline-formula>). Conclusion. The AMH of women of reproductive age is affected by HT. Furthermore, women with the lowest AMH level had higher levels of TgAb and a positive rate of TgAb, and high TgAb levels may cause autoimmune damage to the ovaries.<\/jats:p>","DOI":"10.1155\/2023\/1861752","type":"journal-article","created":{"date-parts":[[2023,12,13]],"date-time":"2023-12-13T22:50:20Z","timestamp":1702507820000},"page":"1-7","source":"Crossref","is-referenced-by-count":2,"title":["Elevated Thyroglobulin Antibody Level is Associated with Decreased Anti-M\u00fcllerian Hormone in Women of Reproductive Age"],"prefix":"10.1155","volume":"2023","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2977-0300","authenticated-orcid":true,"given":"Jazyra","family":"Zynat","sequence":"first","affiliation":[{"name":"Department of Endocrinology, People\u2019s Hospital of Xinjiang Uygur Autonomous Region, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinling","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, People\u2019s Hospital of Xinjiang Uygur Autonomous Region, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, People\u2019s Hospital of Xinjiang Uygur Autonomous Region, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuqing","family":"Xing","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, People\u2019s Hospital of Xinjiang Uygur Autonomous Region, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guzailinuer","family":"Jvlaiti","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, People\u2019s Hospital of Xinjiang Uygur Autonomous Region, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingqing","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, People\u2019s Hospital of Xinjiang Uygur Autonomous Region, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lingling","family":"Dong","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, People\u2019s Hospital of Xinjiang Uygur Autonomous Region, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7228-5656","authenticated-orcid":true,"given":"Yanying","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, People\u2019s Hospital of Xinjiang Uygur Autonomous Region, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.5653\/cerm.2015.42.4.131"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2007.02752.x"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1097\/pap.0b013e3182534868"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1210\/er.2009-0041"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2011.11.014"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1186\/s12958-016-0162-0"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1007\/s12522-015-0227-3"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dew027"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.5114\/aoms.2014.41167"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2012.09.036"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1093\/molehr\/gah015"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/j.maturitas.2011.11.008"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2007.02.014"},{"key":"14","first-page":"19","article-title":"Serum anti-m\u00fcllerian hormone variation throughout the menstrual cycle in healthy regularly menstruating young women","volume":"34","author":"K. 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