{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T07:09:37Z","timestamp":1781334577238,"version":"3.54.1"},"reference-count":39,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,8,8]],"date-time":"2023-08-08T00:00:00Z","timestamp":1691452800000},"content-version":"vor","delay-in-days":219,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ophthalmology"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:p><jats:italic>Aim<\/jats:italic>. The purpose of this study is to assess the prevalence of autoimmune\u2010mediated uveitis in relation to other diseases and to describe the clinical patterns of uveitis in a single tertiary hospital in north Jordan. <jats:italic>Methods<\/jats:italic>. A cross\u2010sectional retrospective review was performed. We included all patients diagnosed with uveitis in King Abdullah University Hospital (KAUH) ophthalmology clinic and\/or patients referred to KAUH rheumatology clinics for evaluation of suspected autoimmune mediated uveitis or for difficult to treat uveitis. This included patients from January 2015 to January 2019. Data collected about patients\u2019 age, sex, anatomical location of the disease, etiology, treatment, complications, and outcomes on vision loss were analyzed. <jats:italic>Results<\/jats:italic>. A total of 221 patients were included in our study. The mean (\u00b1SD) age was 36 (\u00b116) years. A total of 111 patients were female and 110 were male with a ratio of 1\u2009:\u20091. Noninfectious uveitis was found to be more common than infectious uveitis (95% vs. 5% respectively). Autoimmune\u2010mediated uveitis accounted for 40% of the total cases. The most common causes of autoimmune\u2010mediated uveitis included Behcet\u2019s disease (<jats:italic>n<\/jats:italic>\u2009=\u200941, 19%) and seronegative spondyloarthropathy (<jats:italic>n<\/jats:italic>\u2009=\u200929, 13%). The majority of patients (<jats:italic>n<\/jats:italic>\u2009=\u2009207, 94%) were treated with ophthalmic eye drops, cDMARDs (<jats:italic>n<\/jats:italic>\u2009=\u2009101, 46%), biologics (<jats:italic>n<\/jats:italic>\u2009=\u200933, 15%), and colchicine (<jats:italic>n<\/jats:italic>\u2009=\u200930, 14%). <jats:italic>Conclusion<\/jats:italic>. Autoimmune\u2010mediated uveitis, most commonly associated with Behcet\u2019s disease and seronegative spondyloarthropathy, represents a high percentage of uveitis in our area. This implies the need for a high index of suspicion at the time of evaluation.<\/jats:p>","DOI":"10.1155\/2023\/2076728","type":"journal-article","created":{"date-parts":[[2023,8,8]],"date-time":"2023-08-08T17:20:05Z","timestamp":1691515205000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Pattern of Uveitis in a Tertiary Hospital in North Jordan and the Impact of Behcet\u2019s Disease"],"prefix":"10.1155","volume":"2023","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5505-3183","authenticated-orcid":false,"given":"Khaldoon M.","family":"Alawneh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omar A.","family":"Saleh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmoud M.","family":"Smadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatima Kamel","family":"Ababneh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ikhlas Hamed","family":"Ali Mahmoud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Areje M.","family":"Smadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8843-1873","authenticated-orcid":false,"given":"Diala","family":"Alawneh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,8,8]]},"reference":[{"key":"e_1_2_10_1_2","doi-asserted-by":"publisher","DOI":"10.1111\/aos.12987"},{"key":"e_1_2_10_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2007.075754"},{"key":"e_1_2_10_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kes249"},{"key":"e_1_2_10_4_2","first-page":"S53","article-title":"Prevalence of beh\u00e7et\u2019s disease in rural western Turkey: a preliminary report","volume":"22","author":"Cakir N.","year":"2004","journal-title":"Clinical & Experimental Rheumatology"},{"key":"e_1_2_10_5_2","first-page":"51","article-title":"The prevalence of beh\u00e7et\u2019s disease in the north of Jordan: a hospital-based epidemiological survey","volume":"35","author":"Madanat W. 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