{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T21:18:35Z","timestamp":1791235115724,"version":"4.1.0"},"reference-count":38,"publisher":"Wiley","license":[{"start":{"date-parts":[[2023,7,18]],"date-time":"2023-07-18T00:00:00Z","timestamp":1689638400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Basic Research Program of China","doi-asserted-by":"publisher","award":["2020YFC2005401"],"award-info":[{"award-number":["2020YFC2005401"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Basic Research Program of China","doi-asserted-by":"publisher","award":["XCSTS-SD2021-02"],"award-info":[{"award-number":["XCSTS-SD2021-02"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Xicheng Financial, Scientific, and Technological Project","award":["2020YFC2005401"],"award-info":[{"award-number":["2020YFC2005401"]}]},{"name":"Xicheng Financial, Scientific, and Technological Project","award":["XCSTS-SD2021-02"],"award-info":[{"award-number":["XCSTS-SD2021-02"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Clinical Practice"],"published-print":{"date-parts":[[2023,7,18]]},"abstract":"<jats:p>Background. Aspiration pneumonia (AP) is difficult to diagnose and has poor outcomes. This case-control study aimed to explore the risk factors and delineate the antibiotic usage for AP. Methods. Inpatients diagnosed with community-acquired pneumonia (CAP) from 2013 to 2017, enrolled in the urban employee basic medical insurance program in Beijing, were included and classified into the AP (N\u2009=\u20092,885) and non-AP (N\u2009=\u200953,825) groups. Risk factors were identified by logistic regression. Results. Older age (compared to 18\u201364\u2009years, OR for 65\u201379\u2009years: 4.3, 95% CI: 3.8\u20134.9; OR for &gt;80\u2009years: 6.3, 95% CI: 5.6\u20137.2), male (OR: 1.4, 95% CI: 1.3\u20131.5), cerebrovascular disease (OR: 3.1, 95% CI: 2.8\u20133.5), dementia (OR: 2.0, 95% CI: 1.8\u20132.1), vomiting (OR: 1.4, 95% CI: 1.2\u20131.7), Parkinson\u2019s disease (OR: 2.1, 95% CI: 1.8\u20132.4), and epilepsy (OR: 3.2, 95% CI: 2.8\u20133.7) were associated with an increased risk of AP. 92.8% of the AP patients received antibiotic therapy. Among them, patients treated with broad-spectrum antibiotics, antibiotics for injection, and combined antibiotics accounted for 93.3%, 97.9%, and 81.7%, respectively. Conclusions. Older age, male, and several comorbidities were independent risk factors for AP, and combined antibiotics treatments are common, which merits attention in accurate detection of AP in a high-risk population.<\/jats:p>","DOI":"10.1155\/2023\/2198259","type":"journal-article","created":{"date-parts":[[2023,7,18]],"date-time":"2023-07-18T16:50:08Z","timestamp":1689699008000},"page":"1-7","source":"Crossref","is-referenced-by-count":13,"title":["Identifying Risk Factors for Aspiration in Patients Hospitalized with Community-Acquired Pneumonia"],"prefix":"10.1155","volume":"2023","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5736-1534","authenticated-orcid":true,"given":"Tianming","family":"Zhao","sequence":"first","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing 100191, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing 100191, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-2690-3125","authenticated-orcid":true,"given":"Kun","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing 100191, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huan","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing 100191, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lianjun","family":"Lin","sequence":"additional","affiliation":[{"name":"Geriatric Department, Peking University First Hospital, Beijing 100034, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3271-8618","authenticated-orcid":true,"given":"Xueying","family":"Qin","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing 100191, China"},{"name":"Key Laboratory of Epidemiology of Major Diseases (Peking University), Ministry of Education, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing 100191, China"},{"name":"Key Laboratory of Epidemiology of Major Diseases (Peking University), Ministry of Education, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8226-5413","authenticated-orcid":true,"given":"Dafang","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing 100191, China"},{"name":"Key Laboratory of Epidemiology of Major Diseases (Peking University), Ministry of Education, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5554-1678","authenticated-orcid":true,"given":"Yiqun","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing 100191, China"},{"name":"Key Laboratory of Epidemiology of Major Diseases (Peking University), Ministry of Education, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1631-3952","authenticated-orcid":true,"given":"Yonghua","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing 100191, China"},{"name":"Key Laboratory of Epidemiology of Major Diseases (Peking University), Ministry of Education, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-1160"},{"issue":"8","key":"2","first-page":"494","article-title":"The incidence rate and economic burden of community-acquired pneumonia in a working-age population","volume":"6","author":"J. Broulette","year":"2013","journal-title":"American health and drug benefits"},{"issue":"2","key":"3","first-page":"196","article-title":"Community-acquired pneumonia","volume":"77","author":"E. Polverino","year":"2011","journal-title":"Minerva Anestesiologica"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1056\/nejm200103013440908"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2005.00608.x"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1038\/srep38097"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1080\/17512433.2019.1663730"},{"issue":"4","key":"8","first-page":"428","article-title":"Analysis of prevalence rate and risk factors for aspiration pneumonia in elderly inpatients","volume":"36","author":"P. Ning","year":"2017","journal-title":"Chinese Journal of Geriatrics"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2020.06.079"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0140060"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1056\/nejmra1714562"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(74)90598-1"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1007\/bf01690548"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200212-1543oc"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1086\/511159"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1111\/resp.13111"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2015.12.002"},{"key":"18","volume-title":"Beijing Statistical Yearbook 2018","author":"Statistical","year":"2019"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1007\/s00228-015-1997-6"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1513\/annalsats.201709-728oc"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1186\/s12890-015-0064-5"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.23462"},{"key":"23","volume-title":"International Language for Drug Utilization Research (ATC\/DDD)","author":"Methodology","year":"2020"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.4045\/tidsskr.16.0622"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkt301"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.159.17.2058"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2010.12.099"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1378\/chest.124.1.328"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/55.11.m634"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(92)90013-o"},{"key":"31","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/50a.5.m257"},{"key":"32","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.1995.268.3.g389"},{"key":"33","doi-asserted-by":"publisher","DOI":"10.1378\/chest.107.1.290-b"},{"key":"34","doi-asserted-by":"publisher","DOI":"10.1590\/1982-0216\/20202262920"},{"key":"35","doi-asserted-by":"publisher","DOI":"10.1097\/01.ccm.0000206106.65220.59"},{"key":"36","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1997.tb01197.x"},{"key":"37","first-page":"S344","article-title":"Clinical features and prognosis of aspiration pneumonia compared with non-aspiration pneumonia in the elderly patients","volume":"64","author":"H. Wang","year":"2016","journal-title":"Journal of the American Geriatrics Society"},{"key":"38","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2013.01.007"}],"container-title":["International Journal of Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/ijclp\/2023\/2198259.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ijclp\/2023\/2198259.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ijclp\/2023\/2198259.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,18]],"date-time":"2023-07-18T16:50:20Z","timestamp":1689699020000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/ijclp\/2023\/2198259\/"}},"subtitle":[],"editor":[{"given":"Zhongqiu","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2023,7,18]]},"references-count":38,"alternative-id":["2198259","2198259"],"URL":"https:\/\/doi.org\/10.1155\/2023\/2198259","relation":{},"ISSN":["1742-1241","1368-5031"],"issn-type":[{"value":"1742-1241","type":"electronic"},{"value":"1368-5031","type":"print"}],"subject":[],"published":{"date-parts":[[2023,7,18]]}}}