{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T05:15:10Z","timestamp":1782450910568,"version":"3.54.5"},"reference-count":9,"publisher":"Wiley","license":[{"start":{"date-parts":[[2023,4,15]],"date-time":"2023-04-15T00:00:00Z","timestamp":1681516800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Infectious Diseases"],"published-print":{"date-parts":[[2023,4,15]]},"abstract":"<jats:p>Cutaneous leishmaniasis is a neglected tropical disease affecting mostly the exposed skin, causing severe and disfiguring lesions in Ethiopia. In this report, we present two cases of atypical mucocutaneous leishmaniasis; one HIV positive and one HIV negative patient. Cases. A 32-year-old male HIV patient presented with 40\u2009days of bleeding per-rectum and a perianal lesion of 5\u2009years. An erythematous nontender plaque measuring 5\u2009cm by 5\u2009cm was observed over the right perianal area with circumferential constricting firm swelling of the rectum. The patient was cured with AmBisome and miltefosine after an incisional biopsy revealed leishmaniasis. A 40-year-old presented with bleeding per-rectum and stool incontinence of 3\u2009months, generalized body swelling of 2\u2009months, and mass around his anus for ten years. A 6 by 3\u2009cm indurated ulcerating mass surrounding the anus and a fungating circumferential mass of 8\u2009cm were seen above the proximal anal verge. An excisional biopsy revealed leishmaniasis, and the patient was treated with AmBisome but passed away due to complications with colostomy diarrhea. Conclusion. Clinicians should consider atypical mucocutaneous leishmaniasis as a possible diagnosis in patients with chronic skin lesions resembling hemorrhoids and colorectal masses, especially in endemic areas such as Ethiopia, regardless of their HIV status.<\/jats:p>","DOI":"10.1155\/2023\/2768626","type":"journal-article","created":{"date-parts":[[2023,4,15]],"date-time":"2023-04-15T19:50:06Z","timestamp":1681588206000},"page":"1-4","source":"Crossref","is-referenced-by-count":2,"title":["Atypical Mucocutaneous Leishmaniasis Presentation Mimicking Rectal Cancer"],"prefix":"10.1155","volume":"2023","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2451-9731","authenticated-orcid":true,"given":"Helina","family":"Fikre","sequence":"first","affiliation":[{"name":"University of Gondar, Leishmaniasis Research and Treatment Center, Gondar, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0111-407X","authenticated-orcid":true,"given":"Ermias","family":"Teklehaimanot","sequence":"additional","affiliation":[{"name":"University of Gondar, Department of Pathology, Gondar, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rezika","family":"Mohammed","sequence":"additional","affiliation":[{"name":"University of Gondar, Leishmaniasis Research and Treatment Center, Gondar, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-2322-6440","authenticated-orcid":true,"given":"Miklol","family":"Mengistu","sequence":"additional","affiliation":[{"name":"University of Gondar, Department of Surgery, Gondar, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-1234-3296","authenticated-orcid":true,"given":"Bewketu","family":"Abebe","sequence":"additional","affiliation":[{"name":"University of Gondar, Department of Pathology, Gondar, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johan","family":"van Griensven","sequence":"additional","affiliation":[{"name":"Institute of Tropical Medicine, Antwerp, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6627-0474","authenticated-orcid":true,"given":"Saskia","family":"van Henten","sequence":"additional","affiliation":[{"name":"Institute of Tropical Medicine, Antwerp, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","first-page":"2","volume-title":"GUIDELINE FOR DIAGNOSIS AND PREVENTION OF LEISHMANIASIS IN ETHIOPIA","author":"Ethiopian ministry of health","year":"2013"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2012.03.001"},{"key":"3","article-title":"Atypical manifestations of visceral leishmaniasis in patients with HIV in north Ethiopia: a gap in guidelines for the management of opportunistic infections in resource poor settingsle","author":"E. Diro"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.17235\/reed.2016.4038\/2015"},{"key":"5","article-title":"Atypical localization of leishmaniasis in an intestinal polyp","volume":"36","author":"L. Zaffiri","year":"2008","journal-title":"Case Report"},{"key":"6","first-page":"106","article-title":"Sujeet raina 1, rashmi kaul raina 2, anita bodh 3, baldev singh Rana 2 RS 4. Gastrointestinal leishmaniasis in non-endemic region","volume-title":"Journal of the Association of Physicians of India"},{"key":"7","volume-title":"Pathology of the Skin","author":"P. H. McKee","year":"1980","edition":"5th"},{"key":"8","volume-title":"Leishmaniasis Pathology","author":"D. Patrick Emanuel","year":"2013"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0006988"}],"container-title":["Case Reports in Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/criid\/2023\/2768626.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criid\/2023\/2768626.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criid\/2023\/2768626.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,15]],"date-time":"2023-04-15T19:50:12Z","timestamp":1681588212000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/criid\/2023\/2768626\/"}},"subtitle":[],"editor":[{"given":"Antonella","family":"Marangoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2023,4,15]]},"references-count":9,"alternative-id":["2768626","2768626"],"URL":"https:\/\/doi.org\/10.1155\/2023\/2768626","relation":{},"ISSN":["2090-6633","2090-6625"],"issn-type":[{"value":"2090-6633","type":"electronic"},{"value":"2090-6625","type":"print"}],"subject":[],"published":{"date-parts":[[2023,4,15]]}}}