{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T05:05:11Z","timestamp":1764997511518,"version":"3.40.5"},"reference-count":16,"publisher":"Wiley","license":[{"start":{"date-parts":[[2023,1,27]],"date-time":"2023-01-27T00:00:00Z","timestamp":1674777600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Obstetrics and Gynecology"],"published-print":{"date-parts":[[2023,1,27]]},"abstract":"<jats:p>Ovarian hyperthecosis or ovarian stromal hyperplasia is a non-neoplastic functional disorder resulting from the presence of luteinized thecal cells within a hyperplastic ovarian stroma. The condition is more common in postmenopausal women than in those of reproductive age and leads to substantial clinical and laboratory alterations, principally androgenetic alopecia, progressive hirsutism, and elevated testosterone levels. Investigation should include clinical evaluation, laboratory tests, and imaging tests to differentiate between the principal diagnostic hypotheses. The gold standard for diagnosis is histopathology of the ovarian tissue. The present case report describes a woman being followed up as an outpatient at the Santa Casa de Miseric\u00f3rdia Hospital in Vit\u00f3ria, Brazil. The objective in publishing this case report is to add to available data on ovarian hyperthecosis, thus contributing towards improving timely diagnosis and treatment. Early diagnosis and treatment would ensure better quality of life for patients with this condition and better physical and mental health. Moreover, these data should be useful both for the medical community and for future research into this disease.<\/jats:p>","DOI":"10.1155\/2023\/2783464","type":"journal-article","created":{"date-parts":[[2023,1,28]],"date-time":"2023-01-28T01:48:07Z","timestamp":1674870487000},"page":"1-8","source":"Crossref","is-referenced-by-count":1,"title":["Postmenopausal Hyperandrogenism due to Ovarian Hyperthecosis"],"prefix":"10.1155","volume":"2023","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8961-4698","authenticated-orcid":true,"given":"Laryssa Santos","family":"Metzker","sequence":"first","affiliation":[{"name":"Santa Casa de Miseric\u00f3rdia de Vit\u00f3ria Hospital, R. Dr. Jo\u00e3o dos Santos Neves 143, Vila Rubim, Vit\u00f3ria, Esp\u00edrito Santo 29025-023, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0750-6640","authenticated-orcid":true,"given":"Luyanne Azevedo Cabral","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Santa Casa de Miseric\u00f3rdia de Vit\u00f3ria Hospital, R. Dr. Jo\u00e3o dos Santos Neves 143, Vila Rubim, Vit\u00f3ria, Esp\u00edrito Santo 29025-023, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1318-2678","authenticated-orcid":true,"given":"Julia Caroliny Nogueira","family":"Borges","sequence":"additional","affiliation":[{"name":"Santa Casa de Miseric\u00f3rdia de Vit\u00f3ria Hospital, R. Dr. Jo\u00e3o dos Santos Neves 143, Vila Rubim, Vit\u00f3ria, Esp\u00edrito Santo 29025-023, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6669-715X","authenticated-orcid":true,"given":"Mariana Furieri","family":"Guzzo","sequence":"additional","affiliation":[{"name":"Santa Casa de Miseric\u00f3rdia de Vit\u00f3ria Hospital, R. Dr. Jo\u00e3o dos Santos Neves 143, Vila Rubim, Vit\u00f3ria, Esp\u00edrito Santo 29025-023, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8752-7902","authenticated-orcid":true,"given":"Rodrigo Neves","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Santa Casa de Miseric\u00f3rdia de Vit\u00f3ria Hospital, R. Dr. Jo\u00e3o dos Santos Neves 143, Vila Rubim, Vit\u00f3ria, Esp\u00edrito Santo 29025-023, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9975-0332","authenticated-orcid":true,"given":"Lucas Luciano Rocha","family":"Silva","sequence":"additional","affiliation":[{"name":"Santa Casa de Miseric\u00f3rdia de Vit\u00f3ria Hospital, R. Dr. Jo\u00e3o dos Santos Neves 143, Vila Rubim, Vit\u00f3ria, Esp\u00edrito Santo 29025-023, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1993-5669","authenticated-orcid":true,"given":"Rodrigo Monico","family":"Cavedo","sequence":"additional","affiliation":[{"name":"Santa Casa de Miseric\u00f3rdia de Vit\u00f3ria Hospital, R. Dr. Jo\u00e3o dos Santos Neves 143, Vila Rubim, Vit\u00f3ria, Esp\u00edrito Santo 29025-023, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2767-4948","authenticated-orcid":true,"given":"Antonio Chamb\u00f4","family":"Filho","sequence":"additional","affiliation":[{"name":"Santa Casa de Miseric\u00f3rdia de Vit\u00f3ria Hospital, R. Dr. Jo\u00e3o dos Santos Neves 143, Vila Rubim, Vit\u00f3ria, Esp\u00edrito Santo 29025-023, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1007\/s12022-013-9285-4"},{"key":"2","first-page":"7","article-title":"Evaluation and management of postmenopausal hyperandrogenism","author":"J. E. Hall","year":"2021"},{"key":"3","first-page":"413","article-title":"Tumores raros do ov\u00e1rio, \u201cRare ovarian tumors\u201d","volume-title":"Manual de Ginecologia, Federa\u00e7\u00e3o das Sociedades Portuguesas de Obstetr\u00edcia e Ginecologia, Gynecology Handbook, Federation of Portuguese Societies of Obstetrics and Gynecology, Portugal","author":"T. Sim\u00f5es Silva","year":"2009"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2019-232783"},{"key":"5","unstructured":"YanceV. R. V.2016S\u00e3o Paulo, BrazilUniversidade de S\u00e3o Paulo, Faculdade de MedicinaContribui\u00e7\u00e3o das caracter\u00edsticas cl\u00ednicas, Hormonais e radiol\u00f3gicas Para O diagn\u00f3stico Diferencial dos Tumores de ov\u00e1rio Produtores de andr\u00f3genos e Hipertecose Do Estroma Ovariano Em Mulheres na p\u00f3s-Menopausa (Disserta\u00e7\u00e3o),\u201d [\u201cContribution of Clinical, Hormonal and Radiological Features to the Differential Diagnosis of Androgen-Producing Ovarian Tumors and Ovarian Stromal Hyperthecosis in Postmenopausal Women (Dissertation)"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-11-0542"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2011.04040.x"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-11-0542"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2011.04040.x"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-14-0468"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.4103\/ijem.IJEM_553_19"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2265.2003.01792.x"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/j.recli.2015.03.004"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1590\/S0100-72032011000800008"},{"key":"15","first-page":"5","article-title":"Evaluation of Premenopausal Women with Hirsutism","author":"R. 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