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A retrospective data collection was jointly conducted at the Otolaryngology departments of San Camillo Forlanini Hospital and University of Rome \u201cLa Sapienza\u201d from December 2020 to January 2023. Results. A total of 130 patients were included in the study. Monitoring our patients for 18 months, we observed a reduction in nasal polyposis and an improvement in symptoms and their impact on quality of life. Regarding blood tests, a transient increase in blood eosinophils was found in most cases. Total IgE showed a gradual decrease in values. IgG and IgA also showed a slight reduction of values, while remaining within normal ranges. Conclusion. To the best of our knowledge, this is the first study to evaluate the impact of dupilumab on several blood parameters in patients receiving treatment for CRswNP. Further studies are needed to confirm our results and to understand the underlying immunological mechanisms.<\/jats:p>","DOI":"10.1155\/2023\/4027701","type":"journal-article","created":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T17:35:16Z","timestamp":1694799316000},"page":"1-10","source":"Crossref","is-referenced-by-count":18,"title":["Dupilumab\u2019s Impact on Blood Parameters in Nasal Polyposis: 18-Month Follow-Up in Real Life"],"prefix":"10.1155","volume":"2023","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7174-8126","authenticated-orcid":true,"given":"Antonella","family":"Loperfido","sequence":"first","affiliation":[{"name":"Otolaryngology Unit, San Camillo Forlanini Hospital, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Ciofalo","sequence":"additional","affiliation":[{"name":"Department of Sense Organs, Sapienza University, Rome, 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