{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T11:34:37Z","timestamp":1788435277444,"version":"build-2803163510"},"reference-count":41,"publisher":"Wiley","license":[{"start":{"date-parts":[[2023,9,12]],"date-time":"2023-09-12T00:00:00Z","timestamp":1694476800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"GNPC Foundation","award":["GNPC\/FDN\/C4\/KNUST\/18"],"award-info":[{"award-number":["GNPC\/FDN\/C4\/KNUST\/18"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Pregnancy"],"published-print":{"date-parts":[[2023,9,12]]},"abstract":"<jats:p>Hypertensive disorders in pregnancy (HDPs) are no longer seen as \u201ctransitory diseases cured by delivery.\u201d It accounts for up to 50% of maternal deaths. Information concerning HDPs is less in developing countries like Ghana. This study was conducted to find out the prevalence, awareness, risk factors, control, and the birth outcomes of HDPs. This was a retrospective cohort study conducted among pregnant women seeking care in selected health facilities in the Ashanti Region. Data on demographics, HDPs, and its associated birth outcomes were collected. Logistic regression models were used to examine the association of the independent variables with HDPs. The burden of HDPs was 37.2% among the 500 mothers enrolled with chronic hypertension superimposed with preeclampsia accounting for 17.6%, chronic hypertension, 10.2%, and preeclampsia 6.8% whilst gestational hypertension was 2.6%. It was observed that 44% (220) of the mothers had excellent knowledge on HDPs. Oral nifedipine and methyldopa were frequently used for HDP management, and it resulted in a significant reduction in HDP burden from 37.2% to 26.6%. Factors that influenced the increased risk of HDPs were grand multigravida (<jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mtext>AOR<\/a:mtext>\n                        <a:mo>=<\/a:mo>\n                        <a:mn>4.53<\/a:mn>\n                     <\/a:math>\n                  <\/jats:inline-formula>; <jats:inline-formula>\n                     <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mtext>CI<\/c:mtext>\n                        <c:mo>=<\/c:mo>\n                        <c:mn>1.42<\/c:mn>\n                     <\/c:math>\n                  <\/jats:inline-formula>\u201314.42), family history of hypertension (<jats:inline-formula>\n                     <e:math xmlns:e=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                        <e:mtext>AOR<\/e:mtext>\n                        <e:mo>=<\/e:mo>\n                        <e:mn>3.61<\/e:mn>\n                     <\/e:math>\n                  <\/jats:inline-formula>; <jats:inline-formula>\n                     <g:math xmlns:g=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\">\n                        <g:mtext>CI<\/g:mtext>\n                        <g:mo>=<\/g:mo>\n                        <g:mn>1.89<\/g:mn>\n                     <\/g:math>\n                  <\/jats:inline-formula>\u20136.90), and the consumption of herbal preparations (<jats:inline-formula>\n                     <i:math xmlns:i=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\">\n                        <i:mtext>AOR<\/i:mtext>\n                        <i:mo>=<\/i:mo>\n                        <i:mn>2.92<\/i:mn>\n                     <\/i:math>\n                  <\/jats:inline-formula>; <jats:inline-formula>\n                     <k:math xmlns:k=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\">\n                        <k:mtext>CI<\/k:mtext>\n                        <k:mo>=<\/k:mo>\n                        <k:mn>1.15<\/k:mn>\n                     <\/k:math>\n                  <\/jats:inline-formula>\u20137.41) and alcohol (<jats:inline-formula>\n                     <m:math xmlns:m=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M7\">\n                        <m:mtext>AOR<\/m:mtext>\n                        <m:mo>=<\/m:mo>\n                        <m:mn>4.10<\/m:mn>\n                     <\/m:math>\n                  <\/jats:inline-formula>; <jats:inline-formula>\n                     <o:math xmlns:o=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M8\">\n                        <o:mtext>CI<\/o:mtext>\n                        <o:mo>=<\/o:mo>\n                        <o:mn>1.34<\/o:mn>\n                     <\/o:math>\n                  <\/jats:inline-formula>-12.62) during pregnancy. HDPs increased the risk of preterm delivery (<jats:inline-formula>\n                     <q:math xmlns:q=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M9\">\n                        <q:mtext>AOR<\/q:mtext>\n                        <q:mo>=<\/q:mo>\n                        <q:mn>2.66<\/q:mn>\n                     <\/q:math>\n                  <\/jats:inline-formula>; <jats:inline-formula>\n                     <s:math xmlns:s=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M10\">\n                        <s:mtext>CI<\/s:mtext>\n                        <s:mo>=<\/s:mo>\n                        <s:mn>1.29<\/s:mn>\n                     <\/s:math>\n                  <\/jats:inline-formula>\u20135.89), stillbirth (<jats:inline-formula>\n                     <u:math xmlns:u=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M11\">\n                        <u:mtext>AOR<\/u:mtext>\n                        <u:mo>=<\/u:mo>\n                        <u:mn>12.47<\/u:mn>\n                     <\/u:math>\n                  <\/jats:inline-formula>; <jats:inline-formula>\n                     <w:math xmlns:w=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M12\">\n                        <w:mtext>CI<\/w:mtext>\n                        <w:mo>=<\/w:mo>\n                        <w:mn>2.72<\/w:mn>\n                     <\/w:math>\n                  <\/jats:inline-formula>\u201357.24), and undergoing caesarean section (<jats:inline-formula>\n                     <y:math xmlns:y=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M13\">\n                        <y:mtext>AOR<\/y:mtext>\n                        <y:mo>=<\/y:mo>\n                        <y:mn>1.70<\/y:mn>\n                     <\/y:math>\n                  <\/jats:inline-formula>; <jats:inline-formula>\n                     <ab:math xmlns:ab=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M14\">\n                        <ab:mtext>CI<\/ab:mtext>\n                        <ab:mo>=<\/ab:mo>\n                        <ab:mn>1.10<\/ab:mn>\n                     <\/ab:math>\n                  <\/jats:inline-formula>\u20132.61) amongst mothers during delivery. The burden of HDPs is high amongst pregnant mothers seeking care in selected facilities. There is the need for intensified campaign on HDPs in the Ashanti Region of Ghana.<\/jats:p>","DOI":"10.1155\/2023\/4194443","type":"journal-article","created":{"date-parts":[[2023,9,12]],"date-time":"2023-09-12T23:35:08Z","timestamp":1694561708000},"page":"1-12","source":"Crossref","is-referenced-by-count":12,"title":["Prevalence, Awareness, and Control of Hypertensive Disorders amongst Pregnant Women Seeking Healthcare in Ghana"],"prefix":"10.1155","volume":"2023","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2302-1854","authenticated-orcid":true,"given":"Pauline","family":"Boachie-Ansah","sequence":"first","affiliation":[{"name":"Department of Pharmacy Practice, Faculty of Pharmacy and Pharmaceutical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4673-4929","authenticated-orcid":true,"given":"Berko Panyin","family":"Anto","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Practice, Faculty of Pharmacy and Pharmaceutical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1921-7301","authenticated-orcid":true,"given":"Afia Frimpomaa Asare","family":"Marfo","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Practice, Faculty of Pharmacy and Pharmaceutical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9533-7831","authenticated-orcid":true,"given":"Edward Tieru","family":"Dassah","sequence":"additional","affiliation":[{"name":"Department of Population and Family Reproductive Health, School of Public Health, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana"},{"name":"Department of Obstetrics and Gynaecology, Komfo Anokye Teaching Hospital, Kumasi, Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6053-4117","authenticated-orcid":true,"given":"Constance Caroline","family":"Cobbold","sequence":"additional","affiliation":[{"name":"Department of Pharmacotherapeutics and Pharmacy Practice, School of Pharmacy and Pharmaceutical Sciences, University of Cape Coast, Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6940-3831","authenticated-orcid":true,"given":"Morrison","family":"Asiamah","sequence":"additional","affiliation":[{"name":"Department of Electron Microscopy and Histopathology, Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, Accra, Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1111\/jch.12429"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(14)70227-X"},{"issue":"6","key":"3","first-page":"1492","article-title":"The American College of Obstetricians and Gynecologists, 2020.Gestational hypertension and preeclampsia: ACOG practice bulletin summary, number 222","volume":"135","author":"G. 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