{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,21]],"date-time":"2025-12-21T04:19:04Z","timestamp":1766290744846,"version":"3.40.5"},"reference-count":29,"publisher":"Wiley","license":[{"start":{"date-parts":[[2023,11,27]],"date-time":"2023-11-27T00:00:00Z","timestamp":1701043200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Endocrinology"],"published-print":{"date-parts":[[2023,11,27]]},"abstract":"<jats:p>Introduction. A paraganglioma (PGL) is a tumour derived from extra-adrenal chromaffin cells of the sympathetic paravertebral ganglia of the thorax, abdomen, and pelvis. Cardiovascular manifestations predominate but neurological symptoms like seizures can occur requiring a high index of suspicion for prompt diagnosis and treatment. Case Description. A 14-year-old girl was referred to the paediatric neurology unit for recurrent headaches of one-year duration, vomiting of 2\u2009months duration, and an episode of generalized tonic-clonic seizures, 2\u2009weeks prior to presentation. There was an associated history of impaired vision, palpitations, diaphoresis, and easy fatigability. Her blood pressure ranged from 150\/101 to 160\/120\u2009mmHg. The brain CT scan was normal. ECG showed left ventricular hypertrophy. Abdominal USS revealed a right para-aortic mass necessitating 24-hour urine normetanephrine which was markedly elevated\u20131695.34\u2009mcg\/24\u2009h (100\u2013500). An abdominal CT scan confirmed a paraganglioma in the right para-aortic region. A multidisciplinary team consisting of paediatric endocrinologists, radiologists, anaesthetists, paediatric and cardiothoracic surgeons, and the intensive care unit (ICU) team was involved in the peri and postoperative management of the child. Intraoperative challenges were hypertension and hypotension (following tumour excision). She was nursed in the ICU for 48\u2009hours. Histology results confirmed paraganglioma. Postoperative urine normetanephrines done a month after surgery had reverted to normal. Her blood pressure has remained normal 6\u2009months after surgery, and no other symptoms have recurred. Conclusion. In evaluating aetiology of childhood hypertension, endocrine causes must be considered though they are rare. The occurrence of paraganglioma is uncommon and can present in unusual ways such as seizures. Measurement of blood pressure in children is advocated as part of routine health care. Clinicians must explore the aetiology of seizures and not merely control them with anticonvulsant therapy.<\/jats:p>","DOI":"10.1155\/2023\/6637802","type":"journal-article","created":{"date-parts":[[2023,11,27]],"date-time":"2023-11-27T21:20:07Z","timestamp":1701120007000},"page":"1-6","source":"Crossref","is-referenced-by-count":1,"title":["An Atypical Presentation of Childhood Paraganglioma with Seizures: A Case Report and Review of the Literature"],"prefix":"10.1155","volume":"2023","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1314-5236","authenticated-orcid":true,"given":"Elizabeth Eberechi","family":"Oyenusi","sequence":"first","affiliation":[{"name":"Endocrinology and Metabolism Unit, Department of Paediatrics, College of Medicine, University of Lagos, Lagos University Teaching Hospital, Lagos, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9967-5435","authenticated-orcid":true,"given":"Uzoamaka 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