{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T17:33:51Z","timestamp":1773423231289,"version":"3.50.1"},"reference-count":15,"publisher":"Wiley","license":[{"start":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T00:00:00Z","timestamp":1694563200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Vascular Medicine"],"published-print":{"date-parts":[[2023,9,13]]},"abstract":"<jats:p>Reported vascular complications following mRNA-based COVID-19 vaccines are consisting of myocarditis, cerebral venous thrombosis, cerebral vascular thrombosis, and vaccine-induced thrombocytopenia. Here, we describe a case of a 49-year-old woman with left-sided pain above the middle common carotid artery (carotidynia) starting a few days after her second vaccination with an mRNA-based COVID-19 vaccine (Spikevax). Imaging was indicative of transient perivascular inflammation of the carotid artery (TIPIC) syndrome. The diagnostic workup for other immunologically mediated diseases was negative. The inflammation subsided after a course of prednisone and aspirin, and clinical symptoms vanished, but later mildly relapsed in the context of a viral upper respiratory tract infection other than SARS-CoV-2. Carotidynia because of TIPIC syndrome may present as an immunogenic side effect of the newly developed mRNA-based vaccinations against COVID-19. TIPIC syndrome should be considered in new-onset neck pain after vaccination.<\/jats:p>","DOI":"10.1155\/2023\/6679200","type":"journal-article","created":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T23:35:08Z","timestamp":1694648108000},"page":"1-4","source":"Crossref","is-referenced-by-count":1,"title":["Relapsing TIPIC Syndrome after Administration of an mRNA-Based COVID-19 Vaccine"],"prefix":"10.1155","volume":"2023","author":[{"given":"Georgiana C.","family":"Sandu","sequence":"first","affiliation":[{"name":"Department of Neurology and Clinical Neurophysiology, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregor","family":"Weisser","sequence":"additional","affiliation":[{"name":"Center for Internal Medicine, Diabetology and Occupational Medicine, ZIDA Remstal, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Kr\u00e4mer","sequence":"additional","affiliation":[{"name":"Department of Radiology and Nuclear Medicine, Medical Center Esslingen, Academic Teaching Hospital of the University of T\u00fcbingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4529-8491","authenticated-orcid":true,"given":"Matthias","family":"Reinhard","sequence":"additional","affiliation":[{"name":"Department of Neurology and Clinical Neurophysiology, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","first-page":"309","article-title":"Atypical neuralgia","volume":"18","author":"T. 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