{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T16:01:04Z","timestamp":1740153664131,"version":"3.37.3"},"reference-count":21,"publisher":"Wiley","license":[{"start":{"date-parts":[[2023,12,11]],"date-time":"2023-12-11T00:00:00Z","timestamp":1702252800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000072","name":"National Institute of Dental and Craniofacial Research","doi-asserted-by":"publisher","award":["R21DE024850","U54GM133807","U54MD007587"],"award-info":[{"award-number":["R21DE024850","U54GM133807","U54MD007587"]}],"id":[{"id":"10.13039\/100000072","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006545","name":"National Institute on Minority Health and Health Disparities","doi-asserted-by":"publisher","award":["R21DE024850","U54GM133807","U54MD007587"],"award-info":[{"award-number":["R21DE024850","U54GM133807","U54MD007587"]}],"id":[{"id":"10.13039\/100006545","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["R21DE024850","U54GM133807","U54MD007587"],"award-info":[{"award-number":["R21DE024850","U54GM133807","U54MD007587"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R21DE024850","U54GM133807","U54MD007587"],"award-info":[{"award-number":["R21DE024850","U54GM133807","U54MD007587"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Dentistry"],"published-print":{"date-parts":[[2023,12,11]]},"abstract":"<jats:p>Background. Identifying factors related to persistent human papillomavirus (HPV) infection is essential to reduce the incidence of HPV-related cancers. Objective. To evaluate whether gingival\/periodontal inflammation is associated with oral HPV infection. Methods. This cross-sectional study (n\u2009=\u2009740) uses data from the follow-up visit of the San Juan Overweight Adults Longitudinal Study, which recruited overweight\/obese adults aged 40\u201365 from Puerto Rico. Participants completed a dental examination and two interviews (face-to-face\/ACASI) and provided oral rinse samples for HPV detection. Oral inflammation was assessed using two definitions: (1) the number of sites with bleeding on probing (BOP), and (2) the number of teeth with probing pocket depths (PPD)\u2009\u2265\u20094\u2009mm and BOP. Multivariate logistic regression was used to assess the association between oral inflammation and oral HPV. Results. Nearly three-quarters (72%) of participants were female, and 68% had 50 years or older. Participants with HPV had a higher mean number of sites with BOP (15.5 vs. 10.1) and teeth with PPD\u2009\u2265\u20094\u2009mm and BOP (8.5 vs. 3.2) than participants without HPV (<jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mi>p<\/a:mi>\n                        <a:mo>&lt;<\/a:mo>\n                        <a:mn>0.05<\/a:mn>\n                     <\/a:math>\n                  <\/jats:inline-formula>). After adjusting for sex, age, income, and the number of oral sex partners, the odds of having an oral HPV infection increased by 3% (95% confidence interval (CI): 1.00\u20131.06) for any additional sites with BOP and 5% (95% CI: 1.02\u20131.09) for any other teeth with PPD\u2009\u2265\u20094\u2009mm and BOP. Conclusions. We found that oral inflammation was associated with oral HPV infection among adults in Puerto Rico. Future studies need to further investigate the underlying mechanisms.<\/jats:p>","DOI":"10.1155\/2023\/7247976","type":"journal-article","created":{"date-parts":[[2023,12,11]],"date-time":"2023-12-11T20:50:09Z","timestamp":1702327809000},"page":"1-6","source":"Crossref","is-referenced-by-count":1,"title":["Oral Inflammation and Human Papilloma Virus Association among Hispanics"],"prefix":"10.1155","volume":"2023","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2376-7656","authenticated-orcid":true,"given":"Maira A.","family":"Casta\u00f1eda-Avila","sequence":"first","affiliation":[{"name":"Department of Population and Quantitative Health Sciences, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2529-7042","authenticated-orcid":true,"given":"Cynthia M.","family":"P\u00e9rez","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Epidemiology, Graduate School of Public Health, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9543-7237","authenticated-orcid":true,"given":"Jos\u00e9","family":"Vivaldi","sequence":"additional","affiliation":[{"name":"School of Dental Medicine, Ana G. M\u00e9ndez University, San Juan, Puerto Rico, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6178-0168","authenticated-orcid":true,"given":"Elba C.","family":"D\u00edaz-Toro","sequence":"additional","affiliation":[{"name":"Department of Restorative Sciences, School of Dental Medicine, University of Puerto Rico, San Juan, Puerto Rico, USA"},{"name":"Hospital of the University of Puerto Rico Comprehensive Cancer Center, San Juan, Puerto Rico, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8024-1346","authenticated-orcid":true,"given":"Jeslie M.","family":"Ramos-Cartagena","sequence":"additional","affiliation":[{"name":"Division of Cancer Control and Population Sciences, University of Puerto Rico Comprehensive Cancer Center, San Juan, Puerto Rico, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0917-7633","authenticated-orcid":true,"given":"Oelisoa M.","family":"Andriankaja","sequence":"additional","affiliation":[{"name":"Center for Clinical Research and Health Promotion, School of Dental Medicine, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1017-9473","authenticated-orcid":true,"given":"Ana P.","family":"Ortiz","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Epidemiology, Graduate School of Public Health, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico, USA"},{"name":"Division of Cancer Control and Population Sciences, University of Puerto Rico Comprehensive Cancer Center, San Juan, Puerto Rico, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2017.38"},{"issue":"2","key":"2","first-page":"72","article-title":"Prevalence of periodontal disease, its association with systemic diseases and prevention","volume":"1","author":"M. 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