{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:51:08Z","timestamp":1787017868204,"version":"build-2736575974"},"reference-count":48,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,7,7]],"date-time":"2023-07-07T00:00:00Z","timestamp":1688688000000},"content-version":"vor","delay-in-days":187,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003392","name":"Natural Science Foundation of Fujian Province","doi-asserted-by":"publisher","award":["2011D001"],"award-info":[{"award-number":["2011D001"]}],"id":[{"id":"10.13039\/501100003392","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018534","name":"Medical Innovation Project of Fujian Province","doi-asserted-by":"publisher","award":["2011-CXB-47"],"award-info":[{"award-number":["2011-CXB-47"]}],"id":[{"id":"10.13039\/501100018534","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ophthalmology"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:p>\n                    <jats:italic>Objective<\/jats:italic>\n                    . To evaluate the influence of pilocarpine eyedrops on the ocular biometric parameters and whether these parameter changes affect the intraocular lens (IOL) power calculation in patients with primary angle\u2010closure glaucoma (PACG).\n                    <jats:italic>Methods<\/jats:italic>\n                    . Twenty\u2010two PACG patients and fifteen normal subjects were enrolled. Ocular biometric parameters including the axial length (AL), anterior chamber depth (ACD), lens thickness (LT), mean keratometry (Km), and white\u2010to\u2010white distance (WTW) were measured by using a Lenstar LS 900 device before and at least 30\u2009minutes after instillation of 2% pilocarpine eyedrops. Lens position (LP) was calculated, and the IOL power prediction based on the ocular biometric parameters was performed using the Barrett Universal II, Haigis, Hoffer Q, Holladay I, or SRK\/T formulas before and after pilocarpine application.\n                    <jats:italic>Results<\/jats:italic>\n                    . In both PACG and normal groups, pilocarpine eyedrops induced a slight but statistically significant increase in the mean AL (0.01\u2009mm for both groups) and mean LT (0.02\u2009mm and 0.03\u2009mm, respectively) but a significant decrease in the mean ACD (0.03\u2009mm and 0.05\u2009mm, respectively) and mean LP (0.02\u2009mm and 0.04\u2009mm, respectively). No significant changes in the mean Km and WTW were noticed in both groups. In addition, the IOL power calculation revealed insignificant changes before and after the pilocarpine instillation in both groups, regardless of the formula used.\n                    <jats:italic>Conclusions<\/jats:italic>\n                    . Pilocarpine eyedrops can induce slight changes in the ocular biometric parameters including the AL, ACD, LT, and LP. However, these parameter changes will not result in a significant difference in IOL power estimation.\n                  <\/jats:p>","DOI":"10.1155\/2023\/7680659","type":"journal-article","created":{"date-parts":[[2023,7,7]],"date-time":"2023-07-07T16:20:09Z","timestamp":1688746809000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Influence of Pilocarpine Eyedrops on the Ocular Biometric Parameters and Intraocular Lens Power 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