{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T12:19:38Z","timestamp":1766578778073,"version":"3.41.2"},"reference-count":33,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,2,21]],"date-time":"2023-02-21T00:00:00Z","timestamp":1676937600000},"content-version":"vor","delay-in-days":51,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100011821","name":"Ministry of Education \u2013 Kingdom of Saudi Arabi","doi-asserted-by":"publisher","award":["0075-1442-S"],"award-info":[{"award-number":["0075-1442-S"]}],"id":[{"id":"10.13039\/501100011821","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Intelligent Systems"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:p>Breast cancer (BrCa) is the most common disease in women worldwide. Classifying the BrCa image is extremely important for finding BrCa at an earlier stage and monitoring BrCa during treatment. The computer\u2010aided detection methods have been used to interpret BrCa and improve the detection of BrCa during the screening and treatment stages. However, if a new BrCa image is generated for the treatment, it will not classify correctly. The main objective of this research is to classify the BrCa images for newly generated images. The model performs preprocessing, segmentation, feature extraction, and classification. In preprocessing, a hybrid median filtering (HMF) is used to eliminate the noise in the images. The contrast of the images is enhanced using quadrant dynamic histogram equalization (QDHE). Then, ROI segmentation is performed using the USE\u2010Net deep learning model. The CaffeNet model is used for feature extraction on the segmented images, and finally, classification is made using the improved random forest (IRF) with extreme gradient boosting (XGB). The model obtained 97.87% accuracy, 98.45% sensitivity, 95.24% specificity, 98.96% precision, and 98.70% f1\u2010score for ultrasound images. 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