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One of its complications in children is developing multisystemic inflammatory syndrome related to cytokine storm. Anakinra is a recombinant human interleukin-1 (IL-1) receptor antagonist used to suppress the exaggerated inflammatory response in such conditions, and it is potentially lifesaving in a cytokine storm. We present the case of a patient with critical COVID-19 associated with multisystem inflammatory syndrome in children (MIS-C) successfully treated with anakinra intravenous (IV) infusion.<\/jats:p>","DOI":"10.1155\/2023\/8530060","type":"journal-article","created":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:35:06Z","timestamp":1677630906000},"page":"1-4","source":"Crossref","is-referenced-by-count":1,"title":["Use of Continuous Intravenous Anakinra Infusion in Multisystem Inflammatory Syndrome in Children"],"prefix":"10.1155","volume":"2023","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4477-7498","authenticated-orcid":true,"given":"Abdulaziz","family":"Alolayan","sequence":"first","affiliation":[{"name":"Pharmacy Department, Prince Sultan Military Medical City, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdullah S.","family":"Aldamegh","sequence":"additional","affiliation":[{"name":"Pediatrics Department, Unaizah College of Medicine and Medical Sciences, Al-Qassim University, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azzah","family":"Alkhayrat","sequence":"additional","affiliation":[{"name":"Pharmacy Department, Prince Sultan Military Medical City, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1093\/jpids\/piaa069"},{"key":"2","volume-title":"Emergency preparedness and response multisystem in ammatory syndrome in children (MIS-C) associated with coronavirus disease 2019","author":"Centre for Disease Control and Prevention","year":"2020"},{"key":"3","article-title":"Guidance: paediatric multisystem inflammatory syndrome temporally associated with COVID-19","author":"Royal College of Pediatrics and Child Health","year":"2020"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2021680"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)31103-X"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.120.048360"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1186\/s13613-020-00690-8"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-4642(20)30168-1"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.10369"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.m2094"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1016\/j.prrv.2020.07.003"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1080\/14740338.2018.1486819"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1001\/jama.271.23.1836"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1016\/S2665-9913(20)30164-8"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1016\/S2665-9913(20)30127-2"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2020.05.007"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2022.109075"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1038\/jcbfm.2010.103"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1016\/1043-4666(92)90078-6"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1002\/acr2.11135"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30183-5"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.4031"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.79.10.6441-6448.2005"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2022.823847"}],"container-title":["Case Reports in Critical Care"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cricc\/2023\/8530060.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cricc\/2023\/8530060.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cricc\/2023\/8530060.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:35:10Z","timestamp":1677630910000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/cricc\/2023\/8530060\/"}},"subtitle":[],"editor":[{"given":"Luca","family":"Gallelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2023,2,28]]},"references-count":24,"alternative-id":["8530060","8530060"],"URL":"https:\/\/doi.org\/10.1155\/2023\/8530060","relation":{},"ISSN":["2090-6439","2090-6420"],"issn-type":[{"value":"2090-6439","type":"electronic"},{"value":"2090-6420","type":"print"}],"subject":[],"published":{"date-parts":[[2023,2,28]]}}}