{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T19:53:10Z","timestamp":1780343590562,"version":"3.54.1"},"reference-count":20,"publisher":"Wiley","license":[{"start":{"date-parts":[[2023,3,29]],"date-time":"2023-03-29T00:00:00Z","timestamp":1680048000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Anesthesiology"],"published-print":{"date-parts":[[2023,3,29]]},"abstract":"<jats:p>Hemophilia C is a rare bleeding disorder characterized by a deficiency in clotting factor XI (fXI) and has no standard of care for preoperative optimization before cardiac surgery. Normalization of fXI levels in patients with hemophilia C can be achieved with fresh frozen plasma (FFP), which sometimes results in allergic reactions. We present a case of a patient with hemophilia C requiring coronary artery bypass grafting surgery who developed an allergic reaction to FFP. Our report underscores the balance between thrombosis and bleeding risks when devising a perioperative plan for patients with hemophilia C.<\/jats:p>","DOI":"10.1155\/2023\/8973346","type":"journal-article","created":{"date-parts":[[2023,3,29]],"date-time":"2023-03-29T16:50:18Z","timestamp":1680108618000},"page":"1-4","source":"Crossref","is-referenced-by-count":4,"title":["Perioperative Management of a Patient with Hemophilia C and Allergy to Fresh Frozen Plasma"],"prefix":"10.1155","volume":"2023","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4060-133X","authenticated-orcid":true,"given":"Sara","family":"Kianian","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, Stony Brook University Health Science Center, Stony Brook, NY 11794-8480, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6178-7941","authenticated-orcid":true,"given":"Giacomo","family":"Scorsese","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Stony Brook University Health Science Center, Stony Brook, NY 11794-8480, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Zabirowicz","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Stony Brook University Health Science Center, Stony Brook, NY 11794-8480, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy","family":"Poppers","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Stony Brook University Health Science Center, Stony Brook, NY 11794-8480, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1988.tb02409.x"},{"issue":"1","key":"2","first-page":"60","article-title":"Factor XI deficiency: about 20 cases and literature review","volume":"100","author":"Y. 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