{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T17:19:17Z","timestamp":1789838357684,"version":"4.0.1"},"reference-count":23,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,5,11]],"date-time":"2023-05-11T00:00:00Z","timestamp":1683763200000},"content-version":"vor","delay-in-days":130,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Weifang Eye Hospital"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ophthalmology"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. To study the effect of cycloplegia on ocular parameters in children with myopia and hyperopia. <jats:italic>Methods<\/jats:italic>. Forty\u2010two myopia and forty\u2010four hyperopia eyes in children between 5 and 10\u2009years of age were included. Measurements were taken before and after cycloplegia using 1% atropine sulfate ointment. The ocular parameters included central corneal thickness (CCT), corneal curvature (CC), anterior chamber depth (ACD), pupil diameter (PD), axial length (AL), and central retinal thickness (CRT). <jats:italic>Results<\/jats:italic>. There was no significant difference in CCT, CC, and CRT between the two groups without cycloplegia, but the ACD of the myopia (3.64\u2009\u00b1\u20090.28\u2009mm) group was significantly higher than that of hyperopia (3.40\u2009\u00b1\u20090.24\u2009mm; <jats:italic>t<\/jats:italic>\u2009=\u2009\u22124.522; <jats:italic>P<\/jats:italic> &lt; 0.0001). The average PD of the myopia (4.85\u2009\u00b1\u20090.87\u2009mm) group was significantly smaller than that of the hyperopia group (5.47\u2009\u00b1\u20091.15\u2009mm; <jats:italic>t<\/jats:italic>\u2009=\u20092.903; <jats:italic>P<\/jats:italic> &lt; 0.0046). The average AL of myopia (24.25\u2009\u00b1\u20090.77\u2009mm) was significantly higher than that of hyperopia (21.73\u2009\u00b1\u20091.24\u2009mm; <jats:italic>t<\/jats:italic>\u2009=\u200912.084; <jats:italic>P<\/jats:italic> &lt; 0.0001). However, it was found that the average PD of myopia (7.68\u2009\u00b1\u20090.51\u2009mm) was significantly larger than that of hyperopia (7.41\u2009\u00b1\u20090.57\u2009mm; <jats:italic>t<\/jats:italic>\u2009=\u20092.364; <jats:italic>P<\/jats:italic> = 0.0202) under cycloplegia. As for the changes in refractive factors before and after cycloplegia, deepened ACD and enlarged PD were noted in both the groups after cycloplegia. <jats:italic>Conclusions<\/jats:italic>. Cycloplegia not only affects ACD and PD but also leads to the reversal of PD differences between the two groups. Cycloplegia effects enabled us to study changes in all known ocular parameters in a short period.<\/jats:p>","DOI":"10.1155\/2023\/9003942","type":"journal-article","created":{"date-parts":[[2023,5,11]],"date-time":"2023-05-11T21:50:07Z","timestamp":1683841807000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Effects of Cycloplegic Agents on Ocular Parameters in Children with Myopia and Hyperopia"],"prefix":"10.1155","volume":"2023","author":[{"given":"Guangzhi","family":"Qu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bingfeng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saisai","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaocui","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5018-3437","authenticated-orcid":false,"given":"Lei","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuli","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,5,11]]},"reference":[{"key":"e_1_2_12_1_2","unstructured":"Ministry of Education of the People\u2032s Republic of China Eight departments including the Ministry of education and the national health commission jointly issued the implementation plan for comprehensive prevention and control of myopia in children and adolescents 2023 http:\/\/www.moe.gov.cn\/jyb_xwfb\/gzdt_gzdt\/s5987\/201808\/t20180830_346673.html."},{"key":"e_1_2_12_2_2","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.05-1086"},{"key":"e_1_2_12_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/opx.0b013e3181e87dd3"},{"key":"e_1_2_12_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2010.180323"},{"key":"e_1_2_12_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.visres.2012.09.009"},{"key":"e_1_2_12_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0021-5155(02)00479-3"},{"key":"e_1_2_12_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(12)60272-4"},{"key":"e_1_2_12_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/s2214-109x(13)70113-x"},{"key":"e_1_2_12_9_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2018.2658"},{"key":"e_1_2_12_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/cxo.12533"},{"key":"e_1_2_12_11_2","doi-asserted-by":"publisher","DOI":"10.3760\/cma.j.issn.0412-4081.2016.07.009"},{"key":"e_1_2_12_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2012.04.030"},{"key":"e_1_2_12_13_2","doi-asserted-by":"publisher","DOI":"10.3109\/02713683.2010.501944"},{"key":"e_1_2_12_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/opx.0b013e318263c165"},{"key":"e_1_2_12_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/opx.0000000000000627"},{"key":"e_1_2_12_16_2","first-page":"946","article-title":"Factors related to the time and amplitude of change of pupil diameter and spherical equivalent within 1 hour after cyclopentolate hydrochloride instillation in children with different refractive status","volume":"40","author":"Jin C. 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