{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T18:31:34Z","timestamp":1791829894615,"version":"4.3.4"},"reference-count":43,"publisher":"Wiley","license":[{"start":{"date-parts":[[2023,3,30]],"date-time":"2023-03-30T00:00:00Z","timestamp":1680134400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"COOPERATIO Neurosciences","award":["260533\/SVV\/2022"],"award-info":[{"award-number":["260533\/SVV\/2022"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pain Research and Management"],"published-print":{"date-parts":[[2023,3,30]]},"abstract":"<jats:p>Statistical data show that pain intensity in patients with low back pain is associated with a higher BMI, total serum cholesterol, and triacylglycerol levels. The objective of our study was to evaluate how these associations are dependent on the nature of the patient-doctor relationship. Eighty-nine patients hospitalized with chronic low-back pain (50 women, 39 men; average age: 64.5\u2009\u00b1\u200912.7\u2009years) were assessed over a 3-year period. A serum lipid analysis was conducted (LDL-C, HDL-C, and total cholesterols) at admission in parallel with a subjective evaluation of pain intensity, which was assessed using a numeric rating scale. The participating physician assigned, based on their personal interaction with the patient, an attribute of affinity (positive, neutral, and negative) towards them. Current serum lipid levels and pain intensity were correlated relative to these attributes. Pain intensity did not differ between the groups assigned positive or negative attributes of affinity. In patients belonging to the \u201cpositive\u201d group, pain intensity correlated positively with total cholesterol (<jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mi>p<\/a:mi>\n                        <a:mo>=<\/a:mo>\n                        <a:mn>0.01<\/a:mn>\n                     <\/a:math>\n                  <\/jats:inline-formula>) and LDL cholesterol (<jats:inline-formula>\n                     <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mi>p<\/c:mi>\n                        <c:mo>=<\/c:mo>\n                        <c:mn>0.007<\/c:mn>\n                     <\/c:math>\n                  <\/jats:inline-formula>). No correlations were found in the \u201cnegative\u201d group or when the patient-doctor relationship was ignored. We found a significant association between subjectively assessed low back pain intensity and serum levels of total and LDL cholesterol in patients with whom the physician had a positive affinity. A positive affinity with the patients having chronic pain and the patient\u2019s trust in their physicians may ultimately mean that the patient\u2019s statement about pain is more credible, which may retroactively affect the outcome of therapy.<\/jats:p>","DOI":"10.1155\/2023\/9972093","type":"journal-article","created":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T18:18:03Z","timestamp":1680373083000},"page":"1-8","source":"Crossref","is-referenced-by-count":3,"title":["Objective Evaluation of Chronic Low-Back Pain Using Serum Lipids: The Role of the Doctor-Patient Relationship"],"prefix":"10.1155","volume":"2023","author":[{"given":"Tom\u00e1\u0161","family":"Bruthans","sequence":"first","affiliation":[{"name":"Charles University, Third Faculty of Medicine, Department of Physiology, Prague, Czech Republic"},{"name":"Department of Neurology, Hospital Horovice, Horovice, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jana","family":"Vr\u00e1nov\u00e1","sequence":"additional","affiliation":[{"name":"Charles University, Third Faculty of Medicine, Department of Medical Biophysics and Medical Informatics, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8991-1801","authenticated-orcid":true,"given":"Anna","family":"Yamamotov\u00e1","sequence":"additional","affiliation":[{"name":"Charles University, Third Faculty of Medicine, Department of Physiology, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.1993.73.3.639"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aet174"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.36076\/ppj.2013\/16\/e257"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3959(94)00203-q"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/9747148"},{"key":"6","article-title":"The McGill pain questionnaire","volume-title":"Pain Measurement and Assessment","author":"R. 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Leon","year":"2018","journal-title":"Medicine & Science in Sports & Exercise"}],"container-title":["Pain Research and Management"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/prm\/2023\/9972093.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/prm\/2023\/9972093.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/prm\/2023\/9972093.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T18:18:12Z","timestamp":1680373092000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/prm\/2023\/9972093\/"}},"subtitle":[],"editor":[{"given":"Parisa","family":"Gazerani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2023,3,30]]},"references-count":43,"alternative-id":["9972093","9972093"],"URL":"https:\/\/doi.org\/10.1155\/2023\/9972093","relation":{},"ISSN":["1918-1523","1203-6765"],"issn-type":[{"value":"1918-1523","type":"electronic"},{"value":"1203-6765","type":"print"}],"subject":[],"published":{"date-parts":[[2023,3,30]]}}}