{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:49:46Z","timestamp":1787017786041,"version":"build-2736575974"},"reference-count":39,"publisher":"Wiley","license":[{"start":{"date-parts":[[2024,4,18]],"date-time":"2024-04-18T00:00:00Z","timestamp":1713398400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005317","name":"Kermanshah University of Medical Sciences","doi-asserted-by":"publisher","award":["3011130"],"award-info":[{"award-number":["3011130"]}],"id":[{"id":"10.13039\/501100005317","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2024,4,18]]},"abstract":"<jats:p>\n                    Celiac disease is a growing global public health concern. This epidemiological study is aimed at determining the prevalence of celiac disease in Kermanshah, Western Iran, from 2019 to 2021, as well as the frequency of gastrointestinal and nongastrointestinal manifestations associated with the disease. In this cross-sectional study, the medical records of all patients with a confirmed diagnosis of celiac disease between 2019 and 2021 were reviewed. The average population during the study period was 2,058,545. A researcher-developed checklist was used as the data collection tool, and descriptive statistics were employed for data analysis. During the study period, there were 113 patients diagnosed with celiac disease, with a mean age of\n                    <jats:inline-formula>\n                      <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mn>29.1<\/a:mn>\n                        <a:mo>\u00b1<\/a:mo>\n                        <a:mn>16.6<\/a:mn>\n                      <\/a:math>\n                    <\/jats:inline-formula>\n                    years. The three-year prevalence of celiac disease was 5.49 (95% CI: 5.17-5.82) per 100,000 population. Among these patients, 70% (\n                    <jats:inline-formula>\n                      <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mi>n<\/c:mi>\n                        <c:mo>=<\/c:mo>\n                        <c:mn>78<\/c:mn>\n                      <\/c:math>\n                    <\/jats:inline-formula>\n                    ) was female. The most common gastrointestinal manifestations of the disease were abdominal pain (77.8%), constipation (59.3%), and diarrhea (54.9%). Iron-deficiency anemia (64.6%) and vitamin D3 deficiency (46.1%) were the most common nongastrointestinal manifestations. Growth retardation was observed in 39.0% of patients. This study demonstrated a higher prevalence of celiac disease in Kermanshah compared to global statistics. Given the association of celiac disease with other conditions such as diabetes, irritable bowel syndrome, growth retardation, and iron-deficiency anemia, healthcare providers should consider screening patients for celiac disease. Furthermore, community-based education is crucial in raising awareness about the significance of adhering to a proper diet and reducing wheat consumption.\n                  <\/jats:p>","DOI":"10.1155\/2024\/1112812","type":"journal-article","created":{"date-parts":[[2024,4,18]],"date-time":"2024-04-18T18:05:08Z","timestamp":1713463508000},"page":"1-8","source":"Crossref","is-referenced-by-count":1,"title":["Epidemiology of Celiac Disease in Western Iran during 2019-2021"],"prefix":"10.1155","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1450-1554","authenticated-orcid":true,"given":"Maryam","family":"Janatolmakan","sequence":"first","affiliation":[{"name":"Social Development and Health Promotion Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran"},{"name":"Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4206-0282","authenticated-orcid":true,"given":"Mehdi","family":"Zobeiri","sequence":"additional","affiliation":[{"name":"Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5094-5315","authenticated-orcid":true,"given":"Shahab","family":"Rezaeian","sequence":"additional","affiliation":[{"name":"School of Health, Kermanshah University of Medical Sciences, Kermanshah, Iran"},{"name":"Infectious Diseases Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shima","family":"Rostami","sequence":"additional","affiliation":[{"name":"Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehnosh","family":"Akbari","sequence":"additional","affiliation":[{"name":"Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3552-5539","authenticated-orcid":true,"given":"Alireza","family":"Khatony","sequence":"additional","affiliation":[{"name":"Social Development and Health Promotion Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran"},{"name":"Infectious Diseases Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1080\/10408398.2021.1939650"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000000523"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2017.06.037"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.19082\/3883"},{"issue":"1","key":"5","first-page":"29","article-title":"Clinical and laboratory surveys of the Iranian celiac patients","volume":"8","author":"M. Karami","year":"2021","journal-title":"Nutrition and Food Sciences Research"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2020.06.098"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpam.2017.08.002"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2018.11.012"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.3390\/nu13072146"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2018.06.016"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-020-08556-1"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.4103\/sja.SJA_543_18"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.51253\/pafmj.v72i4.7212"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.3389\/fnut.2022.965376"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1002\/jgh3.12741"},{"key":"16","first-page":"172","article-title":"Clinical aspects of growth and growth disorders","volume-title":"Pescovitz OH & Eugster EA Pediatric endocrinology: mechanisms, manifestations, and management","author":"R. 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