{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T14:36:25Z","timestamp":1753886185322,"version":"3.41.2"},"reference-count":37,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,8,6]],"date-time":"2024-08-06T00:00:00Z","timestamp":1722902400000},"content-version":"vor","delay-in-days":218,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pregnancy"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> The novel coronavirus disease 2019 (COVID\u201019) was more devastating in people with comorbidities such as advanced age and immunodeficiency. Another group affected by COVID\u201019 was pregnant women. Immunological changes during pregnancy and conditions such as gestational diabetes and pre\u2010eclampsia that occur during pregnancy also have effects on the fetus. The aim of this study was to analyze the effects of PCR\u2010proven COVID\u201019 infection during pregnancy on fetus and newborn.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> Between December 2019 and October 2021, data from pregnant women with COVID\u201019 symptoms or a history of contact with people with COVID\u201019, infected with PCR\u2010proven COVID\u201019 virus, were analyzed retrospectively. Clinical and laboratory data of pregnant women were analyzed. Death data associated with COVID\u201019 were evaluated. Clinical and laboratory findings of newborns related to COVID\u201019 and mortality data related to COVID\u201019 were recorded. The study received approval from the Gazi Yasargil Training and Research Hospital ethics committee (09.07.2021\/853).<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> We evaluated 327 pregnant women who were followed up in our hospital and whose deliveries ended in live birth, stillbirth, miscarriage, or curettage. One hundred eighty\u2010five (56.6%) of the pregnant women had at least one COVID\u201019\u2010related symptom. We evaluated the data of 306 live births, 21 intrauterine fetal deaths, and 13 postnatal deaths. Among the postnatal deaths, five infants succumbed directly due to COVID\u201019 infection. A total of 23 live\u2010born babies (7.5%) were classified as small for gestational age (SGA), while 80 babies (26.1%) were born before 37 weeks of gestation, and 32 babies (10.4%) were born before 32 weeks. Cord blood gas analysis revealed that 19 infants (6.3%) had pH &lt;\u20097 and base excess (BE)\u2009&lt;\u2009\u221212. The rate of perinatal asphyxia was significantly higher in babies born to mothers who did not survive (<jats:italic>p<\/jats:italic> = 0.027). A considerable number of infants, 119 (40.3%), were admitted to the neonatal intensive care unit (NICU). Among the seven infants with positive PCR results admitted to the NICU, five (4.2%) did not survive.<\/jats:p><jats:p><jats:bold>Conclusion:<\/jats:bold> While COVID\u201019 infection in pregnancy seriously affects mortality and morbidity in pregnant women, it also causes mortality and morbidity on the fetus.<\/jats:p>","DOI":"10.1155\/2024\/1177119","type":"journal-article","created":{"date-parts":[[2024,8,6]],"date-time":"2024-08-06T16:07:09Z","timestamp":1722960429000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Retrospective Analysis of the Impact of SARS\u2010CoV\u20102 (COVID\u201019) on Pregnancy and Neonatal Outcomes"],"prefix":"10.1155","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5224-8583","authenticated-orcid":false,"given":"Leyla","family":"Sero","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0027-0532","authenticated-orcid":false,"given":"Nilufer","family":"Okur","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2130-6821","authenticated-orcid":false,"given":"Duygu","family":"Tun\u00e7el","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7361-3823","authenticated-orcid":false,"given":"Mehmet Nur","family":"Talay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1463-5758","authenticated-orcid":false,"given":"Mustafa F\u0131rat","family":"Ayd\u0131n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7634-3008","authenticated-orcid":false,"given":"Suleyman Cemil","family":"Oglak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,8,6]]},"reference":[{"key":"e_1_2_12_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2020.06.058"},{"key":"e_1_2_12_2_2","doi-asserted-by":"publisher","DOI":"10.15537\/smj.2022.43.6.20220156"},{"key":"e_1_2_12_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciaa675"},{"key":"e_1_2_12_4_2","first-page":"30","article-title":"The impact of coronavirus disease-19 on pregnancy outcomes, a case series","volume":"29","author":"Cetinkaya Demir B.","year":"2023","journal-title":"Obstetrics, Gynaecology and Reproductive Medicine"},{"key":"e_1_2_12_5_2","first-page":"86","article-title":"COVID-19 vaccination status and pregnancy outcome during third wave","volume":"29","author":"Dey M.","year":"2023","journal-title":"Gynecology Obstetrics & Reproductive Medicine"},{"key":"e_1_2_12_6_2","doi-asserted-by":"publisher","DOI":"10.15537\/smj.2022.43.4.20210904"},{"key":"e_1_2_12_7_2","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.202604"},{"key":"e_1_2_12_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2022.01.002"},{"key":"e_1_2_12_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-021-06049-z"},{"key":"e_1_2_12_10_2","doi-asserted-by":"publisher","DOI":"10.1080\/01443615.2023.2218915"},{"key":"e_1_2_12_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jri.2020.103122"},{"key":"e_1_2_12_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2004.00199.x"},{"key":"e_1_2_12_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajogmf.2020.100107"},{"key":"e_1_2_12_14_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.m3320"},{"key":"e_1_2_12_15_2","doi-asserted-by":"publisher","DOI":"10.7189\/jogh.11.05018"},{"key":"e_1_2_12_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000004339"},{"key":"e_1_2_12_17_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI139569"},{"key":"e_1_2_12_18_2","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2020.1850683"},{"key":"e_1_2_12_19_2","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00024.2020"},{"key":"e_1_2_12_20_2","doi-asserted-by":"publisher","DOI":"10.1111\/aji.13306"},{"key":"e_1_2_12_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.crwh.2020.e00243"},{"key":"e_1_2_12_22_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0255994"},{"key":"e_1_2_12_23_2","article-title":"Analysis of maternal coronavirus infections and neonates born to mothers with 2019-nCoV; a systematic review","volume":"8","author":"Muhidin S.","year":"2020","journal-title":"Archives of Academic Emergency Medicine"},{"key":"e_1_2_12_24_2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7024e2"},{"key":"e_1_2_12_25_2","unstructured":"Centers for Disease Control and Prevention. 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