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However, our understanding of the specific factors influencing susceptibility to COVID\u201019 infection among pregnant women with SCT is currently constrained by limited available data. This study aims to determine the risk and protective factors that influence the likelihood of COVID\u201019 infection in this population. A retrospective analysis was done among 151 women with SCT in the reproductive age group. Multivariable analysis was performed to determine the various factors affecting COVID\u201019 infection among pregnant women with SCT. The study found that COVID\u201019\u2010vaccinated pregnant women with SCT had a 90% lower risk of contracting COVID\u201019 and were 9 times more likely to have a COVID\u201019 infection if they had a history of pulmonary conditions such as asthma or chronic obstructive pulmonary disease. The present study further emphasizes the importance of the COVID\u201019 vaccine in preventing infection and safeguarding the health of pregnant women with SCT, particularly those with underlying comorbidities.<\/jats:p>","DOI":"10.1155\/2024\/1595091","type":"journal-article","created":{"date-parts":[[2024,6,12]],"date-time":"2024-06-12T11:04:35Z","timestamp":1718190275000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Risk and Protective Factors for COVID\u201019 Infection among Pregnant Women with Sickle Cell Trait"],"prefix":"10.1155","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5914-0118","authenticated-orcid":false,"given":"Kim Abbegail 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