{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T08:44:43Z","timestamp":1790066683455,"version":"4.0.1"},"reference-count":33,"publisher":"Wiley","license":[{"start":{"date-parts":[[2024,3,29]],"date-time":"2024-03-29T00:00:00Z","timestamp":1711670400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100008713","name":"Diabetes Australia Research Trust","doi-asserted-by":"publisher","award":["APP1197940"],"award-info":[{"award-number":["APP1197940"]}],"id":[{"id":"10.13039\/100008713","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008713","name":"Diabetes Australia Research Trust","doi-asserted-by":"publisher","award":["APP1136735"],"award-info":[{"award-number":["APP1136735"]}],"id":[{"id":"10.13039\/100008713","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005381","name":"Financial Markets Foundation for Children","doi-asserted-by":"publisher","award":["APP1197940"],"award-info":[{"award-number":["APP1197940"]}],"id":[{"id":"10.13039\/501100005381","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005381","name":"Financial Markets Foundation for Children","doi-asserted-by":"publisher","award":["APP1136735"],"award-info":[{"award-number":["APP1136735"]}],"id":[{"id":"10.13039\/501100005381","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1197940"],"award-info":[{"award-number":["APP1197940"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1136735"],"award-info":[{"award-number":["APP1136735"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Diabetes"],"published-print":{"date-parts":[[2024,3,29]]},"abstract":"<jats:p>Objective. Evaluate the mortality risk of childhood-onset type 1 diabetes compared to the general population. Research Design and Methods. The study population, identified from the Australasian Paediatric Endocrinology Group diabetes register, was diagnosed with type 1 diabetes at age\u2009&lt;\u200916 in New South Wales (NSW), Australia, from 1990 to 2010. The register was linked to National Death Index registrations to ascertain timing and cause of death up to 31\/12\/2022. Risk factors for mortality were assessed using multivariable Cox regression models and observed mortality rate compared to \u201cexpected\u201d rates in the Australian general population using indirect-standardized mortality ratios (SMR), overall and by sex and age at diagnosis. Diabetes-related cause of death categories were identified. Results. Of 5,417 children diagnosed with type 1 diabetes, 157 subsequently died, with all-cause mortality of 1.37\/1,000 person years. Increased mortality risk was associated with living in most disadvantaged areas (aHR 1.81 (1.05, 3.11)) but not living in a rural area. Overall SMR was 2.83 (95% CI 2.40, 3.33) with females having higher SMR than males (4.18 vs. 2.19). Most common causes of death recorded were acute diabetes complications (26%), including diabetes ketoacidosis, accident\/misadventure (21%), and chronic diabetes complications (15%). Alcohol and\/or drug use contributed to 17% of deaths. Conclusion. Compared to the general population, higher risk of mortality in people with type 1 diabetes was associated with female sex and living in area of socioeconomic disadvantage. Education about minimizing risk-taking behaviors should be communicated to young adults with type 1 diabetes.<\/jats:p>","DOI":"10.1155\/2024\/1844752","type":"journal-article","created":{"date-parts":[[2024,3,29]],"date-time":"2024-03-29T19:05:09Z","timestamp":1711739109000},"page":"1-7","source":"Crossref","is-referenced-by-count":2,"title":["Excess Mortality in an Inception Cohort of Childhood Diabetes Diagnosed 1990\u20132010"],"prefix":"10.1155","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8988-7407","authenticated-orcid":true,"given":"Samantha J.","family":"Lain","sequence":"first","affiliation":[{"name":"Children\u2019s Hospital at Westmead Clinical School, The University of Sydney, Sydney, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lindsay","family":"Stevens","sequence":"additional","affiliation":[{"name":"Children\u2019s Hospital at Westmead Clinical School, The University of Sydney, Sydney, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6004-576X","authenticated-orcid":true,"given":"Maria E.","family":"Craig","sequence":"additional","affiliation":[{"name":"Institute of Endocrinology and Diabetes, The Children\u2019s Hospital at Westmead, Sydney, Australia"},{"name":"Discipline of Child and Adolescent Health, University of Sydney, Sydney, Australia"},{"name":"Discipline of Paediatrics and Child Health, School of Clinical Medicine, UNSW Health, University of New South Wales, Sydney, Australia"},{"name":"Charles Perkins Centre, University of Sydney, Sydney, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alicia J.","family":"Jenkins","sequence":"additional","affiliation":[{"name":"Baker Heart and Diabetes Institute, Melbourne, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5638-4048","authenticated-orcid":true,"given":"Kirstine J.","family":"Bell","sequence":"additional","affiliation":[{"name":"Charles Perkins Centre, University of Sydney, Sydney, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison","family":"Pryke","sequence":"additional","affiliation":[{"name":"Institute of Endocrinology and Diabetes, The Children\u2019s Hospital at Westmead, Sydney, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kim C.","family":"Donaghue","sequence":"additional","affiliation":[{"name":"Institute of Endocrinology and Diabetes, The Children\u2019s Hospital at Westmead, Sydney, Australia"},{"name":"Discipline of Child and Adolescent Health, University of Sydney, Sydney, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3720-9655","authenticated-orcid":true,"given":"Natasha","family":"Nassar","sequence":"additional","affiliation":[{"name":"Children\u2019s Hospital at Westmead Clinical School, The University of Sydney, Sydney, Australia"},{"name":"Charles Perkins Centre, University of Sydney, Sydney, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1007\/s00592-014-0702-z"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-022-05659-9"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1111\/pedi.13298"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.5694\/mja16.00712"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1111\/dme.12522"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(14)70248-7"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)31506-X"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-007-0824-8"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.26.7.2037"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.2337\/db15-1615"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1515\/JPEM.2000.13.4.363"},{"key":"12","article-title":"Socio-economic indexes for areas (SEIFA), Australia","author":"Australian Bureau of Statistics","year":"2018"},{"key":"13","article-title":"Australian statistical geography standard (ASGS) remoteness structure","author":"Australian Bureau of Statistics","year":"2011"},{"key":"14","volume-title":"ABS Deaths Summary by Age, Sex, Year, State","author":"Australian Bureau of Statistics","year":"2010"},{"key":"15","volume-title":"Australian Population Estimates by Age, Sex, Region","author":"Australian Bureau of Statistics","year":"2016"},{"key":"16","volume-title":"S G: Modern Epidemiology","author":"K. 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