{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T06:02:49Z","timestamp":1791525769082,"version":"4.3.4"},"reference-count":35,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,9,19]],"date-time":"2024-09-19T00:00:00Z","timestamp":1726704000000},"content-version":"vor","delay-in-days":262,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pain Research and Management"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold>Trigeminal postherpetic neuralgia (TPHN) is a severe chronic pain that can lead to various socioeconomic consequences. Therefore, it is necessary to explore optimal treatment options for acute\/subacute herpes zoster (HZ)\u2013related trigeminal neuralgia and prevent the further development of TPHN. High\u2010voltage, long\u2010duration pulsed radiofrequency (HL\u2010PRF) of the Gasserian ganglion is a new surgical intervention used to treat PHN. A ganglion block has been reported to possess anti\u2010inflammatory effects and potential analgesic benefits.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold>We included 83 patients with HZ\u2010related acute\/subacute trigeminal neuralgia admitted from January 1, 2021, to June 1, 2023, and received Gasserian ganglion HL\u2010PRF combined with block. A 6\u2010month follow\u2010up was conducted, including Numerical Rating Scale (NRS) scores, Pittsburgh Sleep Quality Index (PSQI), the incidence of TPHN, the dosage of anticonvulsants and analgesics, efficacy, and adverse events.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold>All patients showed a significant decrease in postoperative NRS scores (<jats:italic>p<\/jats:italic>&lt; 0.05). The NRS scores of the acute HZ group were consistently lower than those of the subacute HZ group at different time points (<jats:italic>p<\/jats:italic>&lt; 0.01). The overall incidence of TPHN from the onset of HZ to 12\u2009weeks is 21.68%. The incidence of TPHN in the acute phase group was 12.77%, significantly lower than the 33.33% in the subacute phase group (<jats:italic>p<\/jats:italic>= 0.024). The effective rate was 74.7% in all patients, at 3\u2009months after the treatment. The effective rate was 82.98% in the acute phase group and 63.89% in the subacute phase group, showing a statistically significant difference (<jats:italic>p<\/jats:italic>= 0.047). The PSQI score of the acute group was consistently lower than that of the subacute group (<jats:italic>p<\/jats:italic>&lt; 0.01). The dosage of analgesics and anticonvulsants used in the acute HZ group was lower than that in the subacute group (<jats:italic>p<\/jats:italic>&lt; 0.01). All patients did not experience serious adverse reactions.<\/jats:p><jats:p><jats:bold>Conclusions:<\/jats:bold>Gasserian ganglion HL\u2010PRF combined with block can be an effective and safe technique to relieve the pain of acute\/subacute zoster\u2010related trigeminal neuralgia and prevent the incidence of TPHN.<\/jats:p>","DOI":"10.1155\/2024\/1992483","type":"journal-article","created":{"date-parts":[[2024,9,19]],"date-time":"2024-09-19T11:40:55Z","timestamp":1726746055000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Efficacy of Gasserian Ganglion High\u2010Voltage, Long\u2010Duration Pulsed Radiofrequency Combined With Block on Acute\/Subacute Zoster\u2010Related Trigeminal Neuralgia"],"prefix":"10.1155","volume":"2024","author":[{"given":"Yinghao","family":"Song","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziheng","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingjing","family":"Guan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haisheng","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiaoling","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6970-0414","authenticated-orcid":false,"given":"Xinzhi","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1433-8139","authenticated-orcid":false,"given":"Bingyu","family":"Ling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,9,19]]},"reference":[{"key":"e_1_2_10_1_2","doi-asserted-by":"publisher","DOI":"10.7326\/istranslatedfrom_aitc201808070_japanese"},{"key":"e_1_2_10_2_2","doi-asserted-by":"publisher","DOI":"10.1080\/00325481.2017.1335574"},{"key":"e_1_2_10_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/nejmcp1403062"},{"key":"e_1_2_10_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciw296"},{"key":"e_1_2_10_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2017.03.004"},{"key":"e_1_2_10_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2010.02999.x"},{"key":"e_1_2_10_7_2","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2019.00708"},{"key":"e_1_2_10_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2010.11.012"},{"key":"e_1_2_10_9_2","first-page":"E633","article-title":"Efficacy of Short-Term Spinal Cord Stimulation in Acute\/Subacute Zoster-Related Pain: A Retrospective Study","volume":"20","author":"Dong D. 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