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To account for randomness and uncertainties in dynamics, the CTMC model was formulated based on deterministic model possible events. A deterministic model\u2019s outputs suggest that disease extinction is feasible when the secondary threshold infection number is below one, while persistence becomes likely when the opposite holds true. Furthermore, the significant contribution of asymptomatic carriers was identified. Results indicate that persistence is more likely to occur when the infection results from asymptomatic, acutely infected, or infectious mosquitoes. Consequently, the CTMC stochastic model is essential in capturing variabilities, randomness, associated probabilities, and validity across different scales, whereas oversimplification and unpredictability of inherent may not be featured in a deterministic model.<\/jats:p>","DOI":"10.1155\/2024\/2130429","type":"journal-article","created":{"date-parts":[[2024,5,4]],"date-time":"2024-05-04T18:05:08Z","timestamp":1714845908000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["The Significance of Stochastic CTMC Over Deterministic Model in Understanding the Dynamics of Lymphatic Filariasis With Asymptomatic Carriers"],"prefix":"10.1155","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2070-3443","authenticated-orcid":false,"given":"Mussa A.","family":"Stephano","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0640-2169","authenticated-orcid":false,"given":"Jacob I.","family":"Irunde","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1745-5509","authenticated-orcid":false,"given":"Maranya M.","family":"Mayengo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7177-0991","authenticated-orcid":false,"given":"Dmitry","family":"Kuznetsov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,5,4]]},"reference":[{"key":"e_1_2_8_1_2","unstructured":"WHO Lymphatic filariasis 2022 World Health Organization https:\/\/www.who.int\/news\u2010room\/fact\u2010sheets\/detail\/lymphatic\u2010filariasis\/."},{"key":"e_1_2_8_2_2","doi-asserted-by":"crossref","unstructured":"AddissD.andEliminate Lymphatic Filariasis The 6th meeting of the Global Alliance to Eliminate Lymphatic Filariasis: a half-time review of lymphatic filariasis elimination and its integration with the control of other neglected tropical diseases 2010 3 no. 1 https:\/\/doi.org\/10.1186\/1756\u20103305\u20103\u2010100 2-s2.0-77958007166.","DOI":"10.1186\/1756-3305-3-100"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0001582"},{"key":"e_1_2_8_4_2","unstructured":"CDC Parasites - lymphatic filariasis: centers for diseases control and prevention 2022 https:\/\/www.cdc.gov\/parasites\/lymphaticfilariasis\/epi.html."},{"key":"e_1_2_8_5_2","unstructured":"Centers for Disease Control and Prevention Lymphatic filariasis 2019 January 2023 https:\/\/www.cdc.gov\/dpdx\/lymphaticfilariasis\/index.htm."},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2011.09.001"},{"key":"e_1_2_8_7_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12889\u2010017\u20104160\u20108"},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13071\u2010016\u20101768\u2010y"},{"key":"e_1_2_8_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473\u20103099(04)00973\u20109"},{"key":"e_1_2_8_10_2","doi-asserted-by":"publisher","DOI":"10.1186\/1756\u20103305\u20101\u20102"},{"key":"e_1_2_8_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2214\u2010109X(20)30286\u20102"},{"key":"e_1_2_8_12_2","unstructured":"AllenL.andBurginA. 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