{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T15:37:54Z","timestamp":1792683474513,"version":"4.5.0"},"reference-count":15,"publisher":"Wiley","license":[{"start":{"date-parts":[[2024,5,10]],"date-time":"2024-05-10T00:00:00Z","timestamp":1715299200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Ophthalmological Medicine"],"published-print":{"date-parts":[[2024,5,10]]},"abstract":"<jats:p>Purpose. We describe a patient with normal tension glaucoma (NTG) of several years whose management was complicated by the presence of a giant internal carotid-ophthalmic artery aneurysm. Observations. A 72-year-old woman presented to our glaucoma clinic with accelerated deterioration of her vision in her left eye (OS) over a 1-month period. Her ophthalmic history was most notable for bilateral NTG diagnosed 3 years prior which had been treated with several laser trabeculoplasty OS and topical bimatoprost 0.01% eye drops in both eyes (OU). Upon evaluation, her visual acuity OS had worsened, and visual field (VF) testing showed extensive progressive losses temporally and pericentrally OS over a year with stable IOP measurements and no neurological complaints. Given her atypical NTG progression, she was referred for an urgent neurological evaluation which revealed an unruptured giant left internal carotid-ophthalmic aneurysm. Following the successful treatment of the aneurysm with platinum coils, she continued to demonstrate additional bilateral ophthalmic changes including further progression of VF loss and RNFL thinning <jats:inline-formula><a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><a:mtext>OS<\/a:mtext><a:mo>&gt;<\/a:mo><a:mtext>OD<\/a:mtext><\/a:math><\/jats:inline-formula> on follow-up. Conclusion and Importance. Overall, this report describes a unique complication in the management of a patient with chronic bilateral NTG in the form of a giant internal carotid-ophthalmic aneurysm. Moreover, it highlights the need for clinicians to maintain a degree of suspicion for compressive lesions of the optic nerve when presented with atypical progression of VFs and\/or visual acuity loss in glaucomatous patients.<\/jats:p>","DOI":"10.1155\/2024\/3878152","type":"journal-article","created":{"date-parts":[[2024,5,11]],"date-time":"2024-05-11T01:46:37Z","timestamp":1715391997000},"page":"1-5","source":"Crossref","is-referenced-by-count":1,"title":["Normal-Tension Glaucoma Complicated by a Giant Internal Carotid-Ophthalmic Artery Aneurysm"],"prefix":"10.1155","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6909-3151","authenticated-orcid":true,"given":"Sudhat","family":"Ashok","sequence":"first","affiliation":[{"name":"Jacobs School of Medicine and Biomedical Sciences, University at Buffalo\/State University of New York (SUNY), 955 Main St., Buffalo, NY 14203, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Pilling","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Ross Eye Institute, University at Buffalo\/State University of New York (SUNY), 1176 Main St., Buffalo, NY 14209, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peterkin","family":"Lee-Kwen","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Buffalo Mercy Hospital Catholic Health System, 565 Abbott Rd., Buffalo, NY 14220, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lee R.","family":"Guterman","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Buffalo Mercy Hospital Catholic Health System, 565 Abbott Rd., Buffalo, NY 14220, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asher","family":"Weiner","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Ross Eye Institute, University at Buffalo\/State University of New York (SUNY), 1176 Main St., Buffalo, NY 14209, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.4103\/0301-4738.133481"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.4103\/0301-4738.86320"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2010.5"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1111\/ceo.14043"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1966.25.2.0219"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1055\/s-0041-1734002"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.120.029296"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(98)91031-4"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1007\/s10792-016-0206-7"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2000.105"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.5935\/0004-2749.20180032"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2014.02.020"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1038\/s41551-021-00813-x"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1167\/tvst.12.3.11"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-3768.2011.02118.x"}],"container-title":["Case Reports in Ophthalmological Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/criopm\/2024\/3878152.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criopm\/2024\/3878152.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criopm\/2024\/3878152.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,11]],"date-time":"2024-05-11T01:46:40Z","timestamp":1715392000000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/criopm\/2024\/3878152\/"}},"subtitle":[],"editor":[{"given":"Stephen G.","family":"Schwartz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2024,5,10]]},"references-count":15,"alternative-id":["3878152","3878152"],"URL":"https:\/\/doi.org\/10.1155\/2024\/3878152","relation":{},"ISSN":["2090-6730","2090-6722"],"issn-type":[{"value":"2090-6730","type":"electronic"},{"value":"2090-6722","type":"print"}],"subject":[],"published":{"date-parts":[[2024,5,10]]}}}