{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T22:53:07Z","timestamp":1785365587803,"version":"3.55.0"},"reference-count":13,"publisher":"Wiley","license":[{"start":{"date-parts":[[2024,4,10]],"date-time":"2024-04-10T00:00:00Z","timestamp":1712707200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Nephrology"],"published-print":{"date-parts":[[2024,4,10]]},"abstract":"<jats:p>Background. The syndrome of tubulointerstitial nephritis and uveitis (TINU) is a rare oculorenal condition, mainly seen in children and women. The underlying cause of this disease is unknown. Case Presentation. We report a 24-year-old male without any past medical history, diagnosed with bilateral uveitis and azotemia. Biopsy revealed tubulointerstitial nephritis, consistent with TINU syndrome. Fluorescein angiogram revealed peripheral retinal vasculitis. Discussion. TINU is a rare disorder that needs to be distinguished from sarcoidosis, Sjogren\u2019s disease, and tuberculosis. Treatment is indicated in patients with progressive renal insufficiency, consisting of steroid therapy. Most patients recover kidney function. Its early recognition is important to offer the best chance of organ preservation.<\/jats:p>","DOI":"10.1155\/2024\/3909755","type":"journal-article","created":{"date-parts":[[2024,4,10]],"date-time":"2024-04-10T18:05:06Z","timestamp":1712772306000},"page":"1-6","source":"Crossref","is-referenced-by-count":2,"title":["TINU: A Multisystemic Inflammatory Disorder\u2014Case Report and Literature Review"],"prefix":"10.1155","volume":"2024","author":[{"given":"Juan","family":"Montejo-Hern\u00e1ndez","sequence":"first","affiliation":[{"name":"Colombian Association of Nephrology and Hypertension, Bogot\u00e1, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2852-1241","authenticated-orcid":true,"given":"Jorge","family":"Rico-Fontalvo","sequence":"additional","affiliation":[{"name":"Colombian Association of Nephrology and Hypertension, Bogot\u00e1, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5142-8216","authenticated-orcid":true,"given":"Jose","family":"Cabrales","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Stanford Healthcare, Stanford University School of Medicine, Palo Alto, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9892-8477","authenticated-orcid":true,"given":"Shuchi","family":"Anand","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Stanford Healthcare, Stanford University School of Medicine, Palo Alto, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1542-0249","authenticated-orcid":true,"given":"Mar\u00eda Cristina","family":"Mart\u00ednez-\u00c1vila","sequence":"additional","affiliation":[{"name":"Epidemiology and Public Health, Polytechnic University of Nicaragua, Managua, Nicaragua"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Duran-Merino","sequence":"additional","affiliation":[{"name":"San Diego Ophthalmology Clinic, Medell\u00edn, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Arias-Restrepo","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Antioquia, Medell\u00edn, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camilo Andr\u00e9s","family":"G\u00f3mez Duran","sequence":"additional","affiliation":[{"name":"CES University, Medell\u00edn, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(75)90390-3"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/s0039-6257(01)00261-2"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1186\/s13023-017-0677-2"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.02-0376"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2017.11.013"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-008-0879-x"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.2215\/cjn.09051209"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/1812271"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2017.04.005"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1097\/ICU.0000000000000421"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-003-1362-3"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000003964"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.01711105"}],"container-title":["Case Reports in Nephrology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crin\/2024\/3909755.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crin\/2024\/3909755.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crin\/2024\/3909755.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,10]],"date-time":"2024-04-10T18:05:09Z","timestamp":1712772309000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/crin\/2024\/3909755\/"}},"subtitle":[],"editor":[{"given":"Yoshihide","family":"Fujigaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2024,4,10]]},"references-count":13,"alternative-id":["3909755","3909755"],"URL":"https:\/\/doi.org\/10.1155\/2024\/3909755","relation":{},"ISSN":["2090-665X","2090-6641"],"issn-type":[{"value":"2090-665X","type":"electronic"},{"value":"2090-6641","type":"print"}],"subject":[],"published":{"date-parts":[[2024,4,10]]}}}