{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,22]],"date-time":"2025-08-22T05:16:23Z","timestamp":1755839783667,"version":"3.41.2"},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T00:00:00Z","timestamp":1731024000000},"content-version":"vor","delay-in-days":312,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Tropical Medicine"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p><jats:italic>Strongyloides stercoralis<\/jats:italic> is a soil\u2010transmitted helminth which is distributed predominately throughout tropical and subtropical regions and is considered a neglected tropical disease. Due to low larval output, traditional microscopic methods lack sensitivity, especially in areas of low endemicity. Serological assays present an opportunity to study the epidemiology of <jats:italic>S. stercoralis<\/jats:italic> in areas of low endemicity such as Jamaica. The current study evaluated the seroprevalence of <jats:italic>S. stercoralis<\/jats:italic> in a selected subpopulation in Jamaica. An analysis was conducted on 311 archived serum samples previously submitted for investigating viral infections during a fever epidemic between 2014 and 2015. Randomly selected, anonymized sera were tested for the presence of <jats:italic>S<\/jats:italic>. <jats:italic>stercoralis<\/jats:italic> IgG antibodies using the AccuDiag <jats:italic>Strongyloides<\/jats:italic> IgG ELISA Kit. Data including age, sex, clinical diagnosis, and the geographic location of sample submission were recorded to delineate trends in demographic variables. The seropositivity rate of <jats:italic>S. stercoralis<\/jats:italic> was 15.43%. The rate among females and males was 16.45% and 14.47%, respectively (<jats:italic>\u03c7<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u20090.2339, <jats:italic>p<\/jats:italic> = 0.629). The highest rate was found in middle adulthood (31\u201350\u2009years) (26.53%; 13\/49). The seroprevalence of <jats:italic>S. stercoralis<\/jats:italic> was significantly highest in a rural Regional Health Authority (33.33%; 14\/42) and least within an urban Health Authority (9.71%; 17\/175). Exposure to <jats:italic>S. stercoralis<\/jats:italic> appears to be highest in the rural Regional Health Authorities with an island\u2010wide exposure rate of 15.43%. The rapid ELISA testing method for the detection of IgG antibodies to <jats:italic>S. stercoralis<\/jats:italic> used in this study may be useful as part of a combined approach to elucidate the epidemiology of this soil\u2010transmitted parasite in Jamaica.<\/jats:p>","DOI":"10.1155\/2024\/4578159","type":"journal-article","created":{"date-parts":[[2024,11,9]],"date-time":"2024-11-09T07:49:12Z","timestamp":1731138552000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The Seroepidemiology of <i>Strongyloides stercoralis<\/i> Infection in Jamaica"],"prefix":"10.1155","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-9964-8364","authenticated-orcid":false,"given":"Anique Vanessa","family":"Chin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1180-3231","authenticated-orcid":false,"given":"Tamara","family":"Thompson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-7811-0688","authenticated-orcid":false,"given":"Cobrini S.","family":"Denton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4781-4998","authenticated-orcid":false,"given":"John F.","family":"Lindo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,11,8]]},"reference":[{"key":"e_1_2_11_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2017.03.037"},{"key":"e_1_2_11_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2017.03.003"},{"key":"e_1_2_11_3_2","doi-asserted-by":"publisher","DOI":"10.1017\/s0031182000081099"},{"key":"e_1_2_11_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/9781555816018"},{"key":"e_1_2_11_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/0470842504"},{"key":"e_1_2_11_6_2","unstructured":"World Health Organization Control of Neglected Tropical Diseases 2024 https:\/\/www.who.int\/teams\/control-of-neglected-tropical-diseases\/soil-transmitted-helminthiases\/strongyloidiasis%23:%7E:text=Strongyloidiasis%2520is%2520an%2520infection%2520caused worldwide%2520."},{"key":"e_1_2_11_7_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268814001563"},{"key":"e_1_2_11_8_2","first-page":"111","article-title":"Changing Patterns in the Prevalence of Intestinal Parasites at the University Hospital of the West Indies (1964\u20131981)","volume":"31","author":"Rawlins S. 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