{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T18:29:22Z","timestamp":1786386562224,"version":"build-2736575974"},"reference-count":18,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,9,26]],"date-time":"2024-09-26T00:00:00Z","timestamp":1727308800000},"content-version":"vor","delay-in-days":269,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Neurological Medicine"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p>\n                    <jats:italic>Atropa belladonna<\/jats:italic>\n                    (\n                    <jats:italic>A. belladonna<\/jats:italic>\n                    ), commonly known as deadly nightshade, is a poisonous plant belonging to the Solanaceae family. The toxic effects of\n                    <jats:italic>A. belladonna<\/jats:italic>\n                    are attributable to its alkaloid content, which possesses potent anticholinergic properties. These alkaloids are responsible for the plant\u2019s toxicity and can cause a range of adverse effects in humans and animals upon ingestion or contact. In this report, we describe two atypical cases of\n                    <jats:italic>A. belladonna<\/jats:italic>\n                    poisoning resulting from accidental ingestion of the plant\u2019s raw leaves, which were referred to the emergency room of a poisoning center in northern Iran. Both patients presented with symptoms of anticholinergic toxicity, including dry mouth, mydriasis, tachycardia, and delirium. The patients were managed conservatively with supportive measures, including hydration and administration of benzodiazepines to control agitation and delirium. With appropriate treatment, both patients showed improvement and were discharged from the hospital.\n                    <jats:italic>A. belladonna<\/jats:italic>\n                    intoxication is associated with a range of clinical manifestations, primarily due to its neurotoxic effects. These manifestations may include flushing, mydriasis, tachycardia, ataxia, agitation, delirium, and urinary retention. The severity of symptoms can vary depending on the amount of the toxin ingested and the individual\u2019s susceptibility. In severe cases,\n                    <jats:italic>A. belladonna<\/jats:italic>\n                    toxicity can lead to seizures, coma, and even death. These cases highlight the importance of awareness regarding the potential toxicity of\n                    <jats:italic>A. belladonna<\/jats:italic>\n                    and the necessity of prompt and appropriate management of its toxicity. In severe cases, physostigmine may be considered for the treatment of neurological symptoms due to the plant\u2019s anticholinergic effects.\n                  <\/jats:p>","DOI":"10.1155\/2024\/5411258","type":"journal-article","created":{"date-parts":[[2024,9,26]],"date-time":"2024-09-26T08:19:03Z","timestamp":1727338743000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Severe Neurotoxicity due to\n                    <i>Atropa belladonna<\/i>\n                    Poisoning: A Case Report and Literature Review"],"prefix":"10.1155","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9186-5445","authenticated-orcid":false,"given":"Seyed Javad","family":"Boskabadi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sima","family":"Ramezaninejad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4835-9349","authenticated-orcid":false,"given":"Zakaria","family":"Zakariaei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,9,26]]},"reference":[{"key":"e_1_2_10_1_2","doi-asserted-by":"publisher","DOI":"10.1177\/0960327111407225"},{"key":"e_1_2_10_2_2","doi-asserted-by":"publisher","DOI":"10.1191\/0960327103ht404oa"},{"key":"e_1_2_10_3_2","doi-asserted-by":"publisher","DOI":"10.1080\/j157v04n04_06"},{"key":"e_1_2_10_4_2","article-title":"Atropa belladonna (deadly nightshade) poisoning in chilhood","volume":"69","author":"Bektas M.","year":"2021","journal-title":"West Indian Medical Journal"},{"key":"e_1_2_10_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2005.09.004"},{"key":"e_1_2_10_6_2","doi-asserted-by":"publisher","DOI":"10.1136\/pmj.79.930.239"},{"key":"e_1_2_10_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2018.04.022"},{"key":"e_1_2_10_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jen.2006.10.013"},{"key":"e_1_2_10_9_2","doi-asserted-by":"publisher","DOI":"10.5152\/tjar.2013.43"},{"key":"e_1_2_10_10_2","doi-asserted-by":"publisher","DOI":"10.33706\/jemcr.998002"},{"key":"e_1_2_10_11_2","first-page":"36","article-title":"Atropa belladonna poisoning in a child with acute psychiatric findings: akut Psikiyatrik Bulgularla Basvuran Olguda Atropa belladonna ile Zehirlenme","volume":"7","author":"Cebeci D.","year":"2020","journal-title":"Journal of Pediatric Emergency and Intensive Care Medicine"},{"key":"e_1_2_10_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/mjt.0b013e3182785eb7"},{"key":"e_1_2_10_13_2","doi-asserted-by":"publisher","DOI":"10.5152\/tjar.2013.43"},{"key":"e_1_2_10_14_2","article-title":"Atropa belladonna intoxication: a case report","volume":"11","author":"Berdai M. A.","year":"2012","journal-title":"The Pan African Medical Journal"},{"key":"e_1_2_10_15_2","article-title":"Psychiatric aspects of a case with deadly nightshade intoxication\/bir \u00c7ocukta Deli ban Otu Zehirlenmesinin Psikiyatrik Y\u00f6nleri","volume":"10","author":"Fidan T.","year":"2011","journal-title":"Eurasian Journal of Emergency Medicine"},{"key":"e_1_2_10_16_2","doi-asserted-by":"publisher","DOI":"10.4274\/cayd.galenos.2018.30092"},{"key":"e_1_2_10_17_2","unstructured":"BerdaiM. A. LabibS. ChetouaniK. andHarandouM. Atropa Belladonna intoxication: a case report 2012."},{"key":"e_1_2_10_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0196-0644(00)70057-6"}],"container-title":["Case Reports in Neurological Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2024\/5411258","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/2024\/5411258","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2024\/5411258","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T17:52:50Z","timestamp":1786384370000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2024\/5411258"}},"subtitle":[],"editor":[{"given":"Peter","family":"Berlit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["10.1155\/2024\/5411258"],"URL":"https:\/\/doi.org\/10.1155\/2024\/5411258","archive":["Portico"],"relation":{},"ISSN":["2090-6668","2090-6676"],"issn-type":[{"value":"2090-6668","type":"print"},{"value":"2090-6676","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"2024-01-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-17","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"5411258"}}