{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T14:38:56Z","timestamp":1753886336858,"version":"3.41.2"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,11,4]],"date-time":"2024-11-04T00:00:00Z","timestamp":1730678400000},"content-version":"vor","delay-in-days":308,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UM1TR004528"],"award-info":[{"award-number":["UM1TR004528"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Infectious Diseases in Obstetrics and Gynecology"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p><jats:bold>Objective:<\/jats:bold> The study was aimed at comparing intrapartum and postpartum outcomes between pregnant patients with and without antenatal COVID\u201019 infection using aggregated, deidentified electronic health record (EHR) data.<\/jats:p><jats:p><jats:bold>Design and Setting:<\/jats:bold> This retrospective cohort study included data from over 80 health care organizations within the TriNetX Analytics Research Network.<\/jats:p><jats:p><jats:bold>Population:<\/jats:bold> Individuals admitted for delivery from Jan 2020 to May 2023 were studied.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> We studied individuals with ICD\u201010 codes for delivery, COVID\u201019 diagnosis, and primary outcomes. We compared the incidence of adverse intrapartum and 30\u2010day postpartum outcomes in those with and without antenatal COVID\u201019.<\/jats:p><jats:p><jats:bold>Main Outcome Measures:<\/jats:bold> The main outcomes compared were obstetric, cardiovascular, neurovascular, and respiratory outcomes within 30 days postpartum.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> Twenty\u2010six thousand nine hundred seventy\u2010four of 369,923 (7%) birthing parents with a delivery encounter had an antenatal COVID\u201019 diagnosis. Compared to matched controls, having COVID\u201019 was associated with an increased risk of postpartum hemorrhage (RR\u20141.24 (CI\u20141.16\u20131.33)), gestational hypertension (RR\u20141.27 (CI\u20141.27\u20131.34)), preeclampsia (RR\u20141.25 (CI\u20141.18\u20131.32)), eclampsia (RR\u20141.66 (CI\u20141.29\u20132.32)), preterm labor (RR\u20141.21 (CI\u20141.21\u20131.34)), cerebral infarction (RR\u20141.74 (CI\u20141.04\u20132.90)), cardiomyopathy (RR\u20142.08 (CI\u20141.30\u20133.32)), heart failure (RR\u20141.55 (CI\u20141.04\u20132.31)), sepsis (RR\u20142.21 (CI\u20141.54\u20133.19)), DVT (RR\u20142.32 (CI\u20141.45\u20133.71)), and pulmonary embolism (RR\u20142.68 (CI\u20141.74\u20132.90)).<\/jats:p><jats:p><jats:bold>Conclusion:<\/jats:bold> Individuals with antenatal COVID\u201019 were more likely to have intrapartum and postpartum obstetric, cardiovascular, neurovascular, and respiratory complications. This data will inform risk stratification and screening for prenatal care providers.<\/jats:p>","DOI":"10.1155\/2024\/5421129","type":"journal-article","created":{"date-parts":[[2024,11,4]],"date-time":"2024-11-04T11:36:59Z","timestamp":1730720219000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Intrapartum and 30\u2010Day Postpartum Complications in Patients With Antenatal COVID\u201019 Infection: A Retrospective Cohort 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