{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T12:37:51Z","timestamp":1771677471514,"version":"3.50.1"},"reference-count":71,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,7,29]],"date-time":"2024-07-29T00:00:00Z","timestamp":1722211200000},"content-version":"vor","delay-in-days":210,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Oncological Medicine"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p>Pediatric chronic myeloid leukemia (pCML) is a rare malignancy accounting for only 2%\u20133% of all childhood leukemias. Due to this rarity, familiarity with pCML is limited among most pediatric practitioners, including even pediatric hemato\u2010oncologists. In low\u2010 and middle\u2010income countries (LMICs), limited financial resources and limited data specific to pCML represent obstacles that healthcare providers must face in diagnosing and treating this rare condition in children. The International CML Foundation (iCMLf) is improving outcomes for people with CML in these countries where resources, diagnostics, and access to medicines may be limited (<jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/www.cml-foundation.org\/lmic-programs.html\">https:\/\/www.cml-foundation.org\/lmic-programs.html<\/jats:ext-link>). Virtual meetings with the purpose of teaching participating pediatricians from LMICs of defined geographical regions were organised by the iCMLf in 2023. At a virtual meeting of the South Asia region, the case of a 14\u2010year\u2010old Indian boy was presented diagnosed with CML in a chronic phase complicated by priapism and loss of vision in his left eye due to hyperleukocytosis. Key aspects of this case are discussed in\u2010depth from the perspective of (i) a pediatric hemato\u2010oncologist practicing in a high\u2010income country, (ii) a pediatric hemato\u2010oncologist practicing in a LMIC, (iii) an adult CML hematologist, and (iv) from the iCMLf in improving the care of children with CML worldwide. Thus by discussing a multifaceted complicated case of pCML in written form as well as pointing to the pediatric module of the iCMLf Knowledge Centre will hopefully contribute to minimize existing knowledge gaps in a rare pediatric malignancy.<\/jats:p>","DOI":"10.1155\/2024\/5534445","type":"journal-article","created":{"date-parts":[[2024,7,29]],"date-time":"2024-07-29T10:35:11Z","timestamp":1722249311000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Cases of Patients Treated in Countries With Limited Resources and Discussed by Experts of the International CML Foundation (iCMLf)\u2014Case No. 1: A Boy Presenting With Priapism and Loss of Vision"],"prefix":"10.1155","volume":"2024","author":[{"given":"Nirmalya Roy","family":"Moulik","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arlene","family":"Harriss-Buchan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guiseppe","family":"Saglio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicola","family":"Evans","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9522-8838","authenticated-orcid":false,"given":"Meinolf","family":"Suttorp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,7,29]]},"reference":[{"key":"e_1_2_8_1_2","unstructured":"https:\/\/knowledge.cml-foundation.org."},{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.1080\/08880018.2023.2301404"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-10-551507"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1080\/10428194.2022.2056178"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2004-2473"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-021-04544-6"},{"key":"e_1_2_8_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41375-018-0179-9"},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.25803"},{"key":"e_1_2_8_9_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12144776"},{"key":"e_1_2_8_10_2","first-page":"135","volume-title":"Therapeutic Apheresis: A Physician\u2019s Handbook","author":"McLeod B.","year":"2004"},{"key":"e_1_2_8_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-022-05024-1"},{"key":"e_1_2_8_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/trf.14512"},{"key":"e_1_2_8_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.25855"},{"key":"e_1_2_8_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.leukres.2014.01.004"},{"key":"e_1_2_8_15_2","first-page":"315","volume-title":"Atlas of procedures in neonatology","author":"Ramasethu J.","year":"2013"},{"key":"e_1_2_8_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/jca.21470"},{"key":"e_1_2_8_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12098-012-0917-3"},{"key":"e_1_2_8_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/mpo.2950150503"},{"key":"e_1_2_8_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.19251"},{"key":"e_1_2_8_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2021.07.001"},{"key":"e_1_2_8_21_2","doi-asserted-by":"publisher","DOI":"10.12659\/AJCR.936266"},{"key":"e_1_2_8_22_2","doi-asserted-by":"publisher","DOI":"10.1080\/08880018.2020.1760408"},{"key":"e_1_2_8_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaapos.2012.04.006"},{"key":"e_1_2_8_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ucl.2021.07.003"},{"key":"e_1_2_8_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2013.11.008"},{"key":"e_1_2_8_26_2","doi-asserted-by":"publisher","DOI":"10.2223\/JPED.1897"},{"key":"e_1_2_8_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2013.07.024"},{"key":"e_1_2_8_28_2","article-title":"Priapism in patients with chronic myeloid leukemia (CML): a systematic review","volume":"92","author":"Ali E.","year":"2021","journal-title":"Acta Bio-Medica"},{"key":"e_1_2_8_29_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2012.09151.x"},{"key":"e_1_2_8_30_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1743-6109.2009.01625.x"},{"key":"e_1_2_8_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.sxmr.2022.06.007"},{"key":"e_1_2_8_32_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002770000199"},{"key":"e_1_2_8_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jemermed.2003.12.011"},{"key":"e_1_2_8_34_2","doi-asserted-by":"publisher","DOI":"10.1002\/jha2.545"},{"key":"e_1_2_8_35_2","first-page":"10","article-title":"Ketamine: review of its pharmacology and its use in pediatric anesthesia","volume":"46","author":"Bergman S. 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