{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T16:39:59Z","timestamp":1792427999223,"version":"4.5.0"},"reference-count":38,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,9,7]],"date-time":"2024-09-07T00:00:00Z","timestamp":1725667200000},"content-version":"vor","delay-in-days":250,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> The potential link between alopecia areata (AA) and eosinophilia is unclear, as well as its clinical manifestations in these patients\u2019 subsets.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> This is a monocentric retrospective observational study in which clinical and laboratory data were summarized and evaluated the AA subset with concurrent eosinophilia.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> In a sample of 205 AA patients, 38 (18.5%) were classified as AA with eosinophilia. Interestingly, this subset of patients had a statistically higher prevalence of atopia and nail abnormalities (<jats:italic>p<\/jats:italic> &lt; 0.05) than AA without eosinophilia. AA patients with eosinophilia had a 3.70 higher odds of more severe hair loss versus age\u2010 and gender\u2010matched AA without eosinophilia.<\/jats:p><jats:p><jats:bold>Conclusions:<\/jats:bold> AA patients with eosinophilia had distinctive clinical and laboratory characteristics, so future studies may potentially explore the use of IL\u20105 inhibitors.<\/jats:p>","DOI":"10.1155\/2024\/5596647","type":"journal-article","created":{"date-parts":[[2024,9,7]],"date-time":"2024-09-07T13:35:56Z","timestamp":1725716156000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Concurrent Eosinophilia Increases the Prevalence of Nail Abnormalities and Severity of Hair Loss in Patients With Alopecia Areata"],"prefix":"10.1155","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2390-6505","authenticated-orcid":false,"given":"Giovanni","family":"Damiani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura Cristina","family":"Gironi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosalynn R. 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