{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T19:20:26Z","timestamp":1773948026635,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","license":[{"start":{"date-parts":[[2024,2,12]],"date-time":"2024-02-12T00:00:00Z","timestamp":1707696000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Nephrology"],"published-print":{"date-parts":[[2024,2,12]]},"abstract":"<jats:p>Myoglobin cast nephropathy occurs in cases of acute renal injury in which large amounts of myoglobin accumulate in the renal tubules, presenting as muscle pain, reddish-brown urine, and elevated creatine kinase levels. Our case describes a 60-year-old male who came to the emergency department with fevers, mild abdominal pain, and constitutional symptoms one day after returning to the United States from a trip to Nigeria. Initial workup demonstrated an acute kidney injury and elevated aminotransferase levels and the patient was started onatovaquone-proguanil for possible malaria given a recent diagnosis in Nigeria. Two days later, the patient was found to have rhabdomyolysis, resulting in a renal biopsy that showed myoglobin cast nephropathy. Previous literature has suggested mechanisms for the development of rhabdomyolysis in malarial infection, including inflammatory processes, direct effect of parasite accumulation, and drug-induced toxicity. Our case further implicates antimalarial therapy as a cause of rhabdomyolysis and increases awareness of myoglobin cast nephropathy as a potential complication of malaria.<\/jats:p>","DOI":"10.1155\/2024\/6764335","type":"journal-article","created":{"date-parts":[[2024,2,12]],"date-time":"2024-02-12T23:35:09Z","timestamp":1707780909000},"page":"1-6","source":"Crossref","is-referenced-by-count":5,"title":["Myoglobin Cast Nephropathy Diagnosed on Renal Biopsy in a Patient Treated for Malarial Infection"],"prefix":"10.1155","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4042-5869","authenticated-orcid":true,"given":"Ramya","family":"Varadarajan","sequence":"first","affiliation":[{"name":"Texas A&M Health Science Center, College Station, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashmi","family":"Patel","sequence":"additional","affiliation":[{"name":"Houston Methodist, Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haneen","family":"Salah","sequence":"additional","affiliation":[{"name":"Houston Methodist, Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neil","family":"Sutaria","sequence":"additional","affiliation":[{"name":"Houston Methodist, Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Barrios","sequence":"additional","affiliation":[{"name":"Houston Methodist, Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luan","family":"Truong","sequence":"additional","affiliation":[{"name":"Houston Methodist, Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lillian","family":"Gaber","sequence":"additional","affiliation":[{"name":"Houston Methodist, Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ziad M.","family":"El-Zaatari","sequence":"additional","affiliation":[{"name":"Houston Methodist, Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2014.05.005"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2016.12.002"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra0801327"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2016.02.026"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.296.6628.1039"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2016.03.059"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1249\/JSR.0000000000000579"},{"issue":"9","key":"8","first-page":"865","article-title":"Rhabdomyolysis induced acute renal failure: a rare complication of falciparum malaria","volume":"62","author":"P. 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