{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T14:35:48Z","timestamp":1753886148471,"version":"3.41.2"},"reference-count":13,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"vor","delay-in-days":274,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Oncological Medicine"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p>Neuroendocrine neoplasms (NENs) are rare in the head and neck region, with the larynx being the most common site. To date, nearly 700 cases of laryngeal neuroendocrine carcinoma (NEC) have been reported in the literature, with an estimated incidence as low as 0.23%. This type of cancer is more prevalent among men aged 50\u201383 who are heavy smokers. NENs encompass paragangliomas and epithelial neoplasms. The latter categories include neuroendocrine tumors, or typical carcinoids, and NECs, or atypical carcinoids. Due to their nonspecific and often misleading presentation, and given the rarity of this condition, optimal management lacks standardization. Treatment typically involves a combination of surgery, chemotherapy, and radiotherapy. We present a case of supraglottic laryngeal NEC in a 61\u2010year\u2010old female nonsmoker. The patient underwent endoscopic excision followed by adjuvant radiotherapy.<\/jats:p>","DOI":"10.1155\/2024\/6844193","type":"journal-article","created":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T11:18:43Z","timestamp":1727781523000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Supraglottic Neuroendocrine Carcinoma: A Case Report and Literature Review"],"prefix":"10.1155","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8728-869X","authenticated-orcid":false,"given":"Renda","family":"Alhabib","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chaker","family":"Zaidi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-3919-7440","authenticated-orcid":false,"given":"Abdulrahman","family":"Alfryyan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanan","family":"Albenayyan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ibrahim","family":"Alotain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,10]]},"reference":[{"key":"e_1_2_10_1_2","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/832194"},{"key":"e_1_2_10_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.21162"},{"key":"e_1_2_10_3_2","doi-asserted-by":"publisher","DOI":"10.7860\/JCDR\/2013\/7756.4294"},{"key":"e_1_2_10_4_2","doi-asserted-by":"publisher","DOI":"10.7860\/JCDR\/2014\/9766.4785"},{"key":"e_1_2_10_5_2","doi-asserted-by":"publisher","DOI":"10.5005\/jp-journals-10003-1258"},{"key":"e_1_2_10_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.23666"},{"key":"e_1_2_10_7_2","doi-asserted-by":"publisher","DOI":"10.18203\/issn.2454-5929.ijohns20211590"},{"key":"e_1_2_10_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12022-022-09708-2"},{"key":"e_1_2_10_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12070-015-0866-z"},{"key":"e_1_2_10_10_2","doi-asserted-by":"publisher","DOI":"10.1159\/000276219"},{"key":"e_1_2_10_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.MLG.0000166179.40750.1B"},{"key":"e_1_2_10_12_2","first-page":"173","article-title":"Neuroendocrine tumors of larynx\u2013two case reports and literature review","volume":"36","author":"Cari\u0107 T.","year":"2012","journal-title":"Collegium Antropologicum"},{"key":"e_1_2_10_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-011-1666-z"}],"container-title":["Case Reports in Oncological Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2024\/6844193","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T11:18:45Z","timestamp":1727781525000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2024\/6844193"}},"subtitle":[],"editor":[{"given":"Jose I.","family":"Mayordomo","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["10.1155\/2024\/6844193"],"URL":"https:\/\/doi.org\/10.1155\/2024\/6844193","archive":["Portico"],"relation":{},"ISSN":["2090-6706","2090-6714"],"issn-type":[{"type":"print","value":"2090-6706"},{"type":"electronic","value":"2090-6714"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"2024-03-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"6844193"}}