{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T14:37:38Z","timestamp":1753886258669,"version":"3.41.2"},"reference-count":10,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,8,5]],"date-time":"2024-08-05T00:00:00Z","timestamp":1722816000000},"content-version":"vor","delay-in-days":217,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Rheumatology"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p>Idiopathic inflammatory myositis (IIM) is an expanding field in rheumatology as more myositis\u2010specific antibodies (MSAs) and myositis\u2010associated antibodies (MAAs) become available for testing. Clinical signs and specific clinical phenotypes are found in the MSA group, with as high as 70% of IIM patients having a positive myositis\u2010specific antibody. Although IIM remains a heterogenous disease, assigning a phenotype to these patients will prove to be critical as we learn which cases require more aggressive therapy and what complications to search for as the disease progresses. The IIM patients for the last 5\u2009years were reviewed and profiled using recently available myositis profile testing at our National Health Laboratory Services. Patients from our rheumatology clinic were categorized according to this antibody profile. Three cases diagnosed with dermatomyositis (DM) were selected for discussion in this article which include a patient with each of the following: anti\u2010transcriptional intermediary factor 1\u2010y (TIF1y) DM, anti\u2010melanoma differentiation\u2010associated protein 5 (MDA 5) DM, and anti\u2010signal recognition particle (SRP) DM.<\/jats:p>","DOI":"10.1155\/2024\/7410630","type":"journal-article","created":{"date-parts":[[2024,8,5]],"date-time":"2024-08-05T11:48:19Z","timestamp":1722858499000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Mystical Myositis: A Case Series from Kalafong Provincial Tertiary Hospital, Pretoria, South Africa"],"prefix":"10.1155","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4069-2238","authenticated-orcid":false,"given":"Michael","family":"Myburgh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,8,5]]},"reference":[{"key":"e_1_2_7_1_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-021-00321-x"},{"key":"e_1_2_7_2_2","first-page":"199","article-title":"Idiopathic inflammatory myopathies: one year in review 2022, clinical and experimental","volume":"41","author":"Dourado E.","year":"2023","journal-title":"Rheumatology"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11926-018-0798-1"},{"key":"e_1_2_7_4_2","first-page":"105","article-title":"Utility of myositis specific autoantibodies for treatment selection in myositis, current treatment options","volume":"8","author":"Dominguez M. 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