{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T02:54:58Z","timestamp":1747191298081,"version":"3.40.5"},"reference-count":16,"publisher":"Wiley","license":[{"start":{"date-parts":[[2024,1,16]],"date-time":"2024-01-16T00:00:00Z","timestamp":1705363200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Dermatological Medicine"],"published-print":{"date-parts":[[2024,1,16]]},"abstract":"<jats:p>Dermal metastasis is a rare manifestation of visceral disease, and esophageal adenocarcinomas represent around only 1% of primaries that present with cutaneous metastasis. In this case, we discuss a patient who presented with a painless submental mass and extensive right neck cutaneous induration and erythema. Core needle biopsy demonstrated poorly differentiated adenocarcinoma. Blood testing also demonstrated elevated carbohydrate antigen 19-9, carcinoembryonic antigen, and alkaline phosphatase. PET\/CT followed by esophagoscopy led to the diagnosis of esophageal signet-cell adenocarcinoma primary with isolated dermal metastasis. The patient was started on palliative radiotherapy and passed away two months later from a suspected thoracic fistula and hydropneumothorax.<\/jats:p>","DOI":"10.1155\/2024\/7951391","type":"journal-article","created":{"date-parts":[[2024,1,16]],"date-time":"2024-01-16T19:05:10Z","timestamp":1705431910000},"page":"1-5","source":"Crossref","is-referenced-by-count":0,"title":["Metastatic Esophageal Adenocarcinoma Presenting as Neck Dermal Metastasis"],"prefix":"10.1155","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4748-3770","authenticated-orcid":true,"given":"Sara","family":"Ibrahim-Shaikh","sequence":"first","affiliation":[{"name":"School of Medicine, Indiana University, Indianapolis, Indiana, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4834-2769","authenticated-orcid":true,"given":"Noah","family":"Shaikh","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, West Virginia University, Morgantown, West Virginia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0500-9939","authenticated-orcid":true,"given":"Nour","family":"Daboul","sequence":"additional","affiliation":[{"name":"Department of Hematology\/Oncology, West Virginia University, Morgantown, West Virginia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esra","family":"Alshaikhnassir","sequence":"additional","affiliation":[{"name":"Department of Pathology, West Virginia University, Morgantown, West Virginia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-2628-9378","authenticated-orcid":true,"given":"Maria","family":"Hafez","sequence":"additional","affiliation":[{"name":"Department of Hematology\/Oncology, West Virginia University, Morgantown, West Virginia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4771-4866","authenticated-orcid":true,"given":"Monika E.","family":"Freiser","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, West Virginia University, Morgantown, West Virginia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.4172\/1948-5956.1000131"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.24834"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1007\/s12094-006-0178-6"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.4103\/ijnm.ijnm_66_19"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2012.05635.x"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.12659\/AJCR.883127"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/1657310"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2007.01.034"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.4103\/1947-2714.118918"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.3322\/canjclin.55.2.74"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1080\/003655202762671215"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v16.i30.3793"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/205417"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1055\/s-0034-1398791"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1097\/sap.0b013e318248b5e9"},{"key":"16","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijscr.2016.10.063","article-title":"Subcutaneous metastases from early stage esophageal adenocarcinoma case report","volume":"29","author":"S. 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