{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T04:22:03Z","timestamp":1769055723783,"version":"3.49.0"},"reference-count":17,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,6,8]],"date-time":"2024-06-08T00:00:00Z","timestamp":1717804800000},"content-version":"vor","delay-in-days":159,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovascular Therapeutics"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> There is limited available data regarding the impact of cycle length (CL) prolongation when converting atrial fibrillation (AF) to organized atrial tachycardia (AT) and its effect on clinical outcomes.<\/jats:p><jats:p><jats:bold>Methods and Method:<\/jats:bold> We retrospectively screened and included a cohort of 132 patients with persistent or long\u2010standing persistent AF who underwent circumferential pulmonary vein isolation (CPVI) and left atrial substrate modification (LASM) between January 2015 and October 2019. In all 132 consecutive patients, persistent AF was successfully converted into organized AT. For cases with recurrence after a 3\u2010month blanking period, a repeat procedure was conducted.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> We observed a notable prolongation in CL after ablation (average increase of 56.6 \u00b1 30\u2009ms). Following a median follow\u2010up duration of 9.5 \u00b1 5.1 months, 27 patients experienced recurrence. Through receiver operating curve (ROC) analysis, a prolonged CL cut\u2010off of 42.5\u2009ms was identified, with a specificity of 71% and a sensitivity of 59.4%. Patients were categorized into two groups: those with CL less than 42.5\u2009ms (group A, <jats:italic>n<\/jats:italic> = 48) and those with CL more than 42.5\u2009ms (group B, <jats:italic>n<\/jats:italic> = 84). The Kaplan\u2013Meier survival curves demonstrated a significantly higher recurrence\u2010free rate after catheter ablation in group B compared to group A (<jats:italic>p<\/jats:italic> = 0.002).<\/jats:p><jats:p><jats:bold>Conclusions:<\/jats:bold> Upon termination of persistent AF into AT during ablation, it was found that CL prolongation beyond 42.5\u2009ms was associated with improved freedom from arrhythmia.<\/jats:p>","DOI":"10.1155\/2024\/8880826","type":"journal-article","created":{"date-parts":[[2024,6,8]],"date-time":"2024-06-08T12:17:58Z","timestamp":1717849078000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Impact of Prolonged Cycle Length Resulting From Conversion of Atrial Fibrillation to Atrial Tachycardia on Ablation Outcome in Persistent Atrial Fibrillation Ablation"],"prefix":"10.1155","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5401-3232","authenticated-orcid":false,"given":"Jialing","family":"He","sequence":"first","affiliation":[{"name":"Department of Cardiology The Affiliated Hospital of Southwest Jiaotong University The Third People\u2019s Hospital of Chengdu Cardiovascular Disease Research Institute of Chengdu  Chengdu Sichuan China  cd3hospital.com"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-8615-7620","authenticated-orcid":false,"given":"Guoshu","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Cardiology The Affiliated Hospital of Southwest Jiaotong University The Third People\u2019s Hospital of Chengdu Cardiovascular Disease Research Institute of Chengdu  Chengdu Sichuan China  cd3hospital.com"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-6770-527X","authenticated-orcid":false,"given":"Duan","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Cardiology The Affiliated Hospital of Southwest Jiaotong University The Third People\u2019s Hospital of Chengdu Cardiovascular Disease Research Institute of Chengdu  Chengdu Sichuan China  cd3hospital.com"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-8155-4563","authenticated-orcid":false,"given":"Yongxin","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Cardiology The Affiliated Hospital of Southwest Jiaotong University The Third People\u2019s Hospital of Chengdu Cardiovascular Disease Research Institute of Chengdu  Chengdu Sichuan China  cd3hospital.com"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8828-126X","authenticated-orcid":false,"given":"Guijun","family":"He","sequence":"additional","affiliation":[{"name":"Department of Cardiology The Affiliated Hospital of Southwest Jiaotong University The Third People\u2019s Hospital of Chengdu Cardiovascular Disease Research Institute of Chengdu  Chengdu Sichuan China  cd3hospital.com"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-1762-8747","authenticated-orcid":false,"given":"Xianchen","family":"Yang","sequence":"additional","affiliation":[{"name":"Physical Examination Department Modern Hospital of Sichuan  Chengdu Sichuan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-3308-7195","authenticated-orcid":false,"given":"Zhen","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Cardiology The Affiliated Hospital of Southwest Jiaotong University The Third People\u2019s Hospital of Chengdu Cardiovascular Disease Research Institute of Chengdu  Chengdu Sichuan China  cd3hospital.com"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,6,8]]},"reference":[{"key":"e_1_2_11_1_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1995.00430050045005"},{"key":"e_1_2_11_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehu359"},{"key":"e_1_2_11_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehaa612"},{"key":"e_1_2_11_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1408288"},{"key":"e_1_2_11_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehp063"},{"key":"e_1_2_11_6_2","doi-asserted-by":"publisher","DOI":"10.1056\/EVIDoa2200141"},{"key":"e_1_2_11_7_2","first-page":"1519","article-title":"Efficacy and safety of low voltage area ablation for atrial fibrillation: a systematic review and meta-analysis","volume":"60","author":"Jia H.","year":"2023","journal-title":"Journal of Interventional Cardiac Electrophysiology"},{"key":"e_1_2_11_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2008.01126.x"},{"key":"e_1_2_11_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2008.09.031"},{"key":"e_1_2_11_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2010.01.038"},{"key":"e_1_2_11_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.09.060"},{"key":"e_1_2_11_12_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000130645.95357.97"},{"key":"e_1_2_11_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2013.06.007"},{"key":"e_1_2_11_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2016.12.033"},{"key":"e_1_2_11_15_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.92.7.1954"},{"key":"e_1_2_11_16_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.98.20.2202"},{"key":"e_1_2_11_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eum208"}],"container-title":["Cardiovascular Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2024\/8880826","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,6]],"date-time":"2025-01-06T14:34:31Z","timestamp":1736174071000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2024\/8880826"}},"subtitle":[],"editor":[{"given":"Hangang","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["10.1155\/2024\/8880826"],"URL":"https:\/\/doi.org\/10.1155\/2024\/8880826","archive":["Portico"],"relation":{},"ISSN":["1755-5914","1755-5922"],"issn-type":[{"value":"1755-5914","type":"print"},{"value":"1755-5922","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"2023-11-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-11","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-08","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"8880826"}}