{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T02:53:00Z","timestamp":1793242380455,"version":"4.5.0"},"reference-count":46,"publisher":"Wiley","license":[{"start":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T00:00:00Z","timestamp":1716422400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100017594","name":"Medical Science and Technology Project of Zhejiang Province","doi-asserted-by":"publisher","award":["2019KY457"],"award-info":[{"award-number":["2019KY457"]}],"id":[{"id":"10.13039\/501100017594","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Canadian Respiratory Journal"],"published-print":{"date-parts":[[2024,5,23]]},"abstract":"<jats:p>\n                    <jats:italic>Background and Objective<\/jats:italic>\n                    . To explore the effect of respiratory muscle training on children with bronchiectasis.\n                    <jats:italic>Methods<\/jats:italic>\n                    . Participants underwent respiratory muscle training for 24\u2009weeks. The main results were changes in respiratory muscle strength and pulmonary function indices (forced expiratory volume in 1\u2009s (FEV1), forced vital capacity (FVC), FEV1\/FVC, peak expiratory flow rate (PEF), forced expiratory flow 25\u201375% (FEF25\u201375%), and maximal midexpiratory flow 75\/25 (MMEF75\/25)) before, 12\u2009weeks after, and 24\u2009weeks after the intervention. The secondary outcomes were changes in the exercise load and work rate, exercise work, Leicester Cough Questionnaire (LCQ) scale, and Fatigue Severity Scale (FSS).\n                    <jats:italic>Results<\/jats:italic>\n                    . Compared with before the intervention, after 24\u2009weeks of respiratory muscle training, the maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP) were significantly enhanced (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                      <mml:mi>P<\/mml:mi>\n                      <mml:mo>&lt;<\/mml:mo>\n                      <mml:mn>0.05<\/mml:mn>\n                    <\/mml:math>\n                    ), while FVC, FEV1, and PEF were significantly increased (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                      <mml:mi>P<\/mml:mi>\n                      <mml:mo>&lt;<\/mml:mo>\n                      <mml:mn>0.01<\/mml:mn>\n                    <\/mml:math>\n                    ). FEF25\u201375 and MMEF75\/25 values showed significant improvement compared to those before training (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                      <mml:mi>P<\/mml:mi>\n                      <mml:mo>&lt;<\/mml:mo>\n                      <mml:mn>0.05<\/mml:mn>\n                    <\/mml:math>\n                    ). The exercise loading, work, and exercise work rate of expiratory muscle training were significantly improved compared to those before intervention (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\">\n                      <mml:mi>P<\/mml:mi>\n                      <mml:mo>&lt;<\/mml:mo>\n                      <mml:mn>0.05<\/mml:mn>\n                    <\/mml:math>\n                    ). The LCQ score increased significantly (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\">\n                      <mml:mi>P<\/mml:mi>\n                      <mml:mo>&lt;<\/mml:mo>\n                      <mml:mtext>\u2009<\/mml:mtext>\n                      <mml:mn>0.001<\/mml:mn>\n                    <\/mml:math>\n                    ), and the FSS score decreased significantly (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\">\n                      <mml:mi>P<\/mml:mi>\n                      <mml:mo>&lt;<\/mml:mo>\n                      <mml:mtext>\u2009<\/mml:mtext>\n                      <mml:mn>0.001<\/mml:mn>\n                    <\/mml:math>\n                    ).\n                    <jats:italic>Conclusion<\/jats:italic>\n                    . Incremental load respiratory muscle training effectively improved children\u2019s lung function over the long term, improved the strength of their inspiratory and expiratory muscles, and improved their quality of life.\n                  <\/jats:p>","DOI":"10.1155\/2024\/8884030","type":"journal-article","created":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T18:50:09Z","timestamp":1716490209000},"page":"1-7","source":"Crossref","is-referenced-by-count":7,"title":["Incremental Load Respiratory Muscle Training Improves Respiratory Muscle Strength and Pulmonary Function in Children with Bronchiectasis"],"prefix":"10.1155","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1577-3757","authenticated-orcid":true,"given":"Xiaolong","family":"Chen","sequence":"first","affiliation":[{"name":"Rehabilitation Medicine Center, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou 325027, Zhejiang, China"},{"name":"Intelligent Rehabilitation Research Center, 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China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1822-2221","authenticated-orcid":true,"given":"Bingbing","family":"Zeng","sequence":"additional","affiliation":[{"name":"Center of Traditional Chinese Medicine, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou 325027, Zhejiang, 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