{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T18:29:25Z","timestamp":1786386565643,"version":"build-2736575974"},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,7,17]],"date-time":"2024-07-17T00:00:00Z","timestamp":1721174400000},"content-version":"vor","delay-in-days":198,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Neurological Medicine"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p>\n                    <jats:italic>Introduction<\/jats:italic>\n                    . Longitudinal extensive transverse myelitis (LETM) has four main causes: inflammatory, malnutrition, vascular, and infectious causes. Among the commonly described viral causes leading to LETM are the\n                    <jats:italic>Herpesviridae<\/jats:italic>\n                    family, HIV, and HTLV\u20101.\n                    <jats:italic>Case Presentation<\/jats:italic>\n                    . A 43\u2010year\u2010old man presented with asymmetric weakness of the lower limbs (the left side was weaker), urinary retention, and flank pain. The symptoms began five days after shingle eruption and progressed over twelve days. He was diagnosed with longitudinal extensive transvers myelitis extending from T4 to T6, which corresponded to the same dermatome involved in shingles. The PCR result of cerebrospinal fluid was positive for varicella\u2010zoster virus with a viral load of 500 copies\/ml. Additionally, the initial HIV enzyme\u2010linked immunosorbent assay (ELISA) test was positive, and his CD4 count was 72\u2009cells\/mm\n                    <jats:sup>3<\/jats:sup>\n                    . Other lab results were normal. Based on the appearance of LETM in the thoracic MRI at T4\u2010T6, VZV myelitis was diagnosed, and treatment was initiated with acyclovir (30 mg\/kg divided daily for twenty\u2010one days), methylprednisolone (1 g\/day for three days), prophylactic antibiotics (trimethoprim\/sulfamethoxazole, rifampin, and isoniazid), and antiretroviral therapy (dolutegravir and Truvada). After 2\u2010month follow\u2010up, he was nearly free of symptoms.\n                    <jats:italic>Conclusion<\/jats:italic>\n                    . Infection is one of the critical causes of transverse myelitis. When a patient presents with skin shingles along with myelopathy, varicella\u2010zoster myelitis should be considered, and the patient should be evaluated in terms of immune system dysfunction. Treatment with acyclovir has been shown to be effective in reducing clinical symptoms in such cases.\n                  <\/jats:p>","DOI":"10.1155\/2024\/9027198","type":"journal-article","created":{"date-parts":[[2024,7,17]],"date-time":"2024-07-17T23:49:37Z","timestamp":1721260177000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Longitudinal Extensive Transverse Myelitis due to Varicella\u2010Zoster Virus Infection in an Undiagnosed HIV\u2010Positive Patient"],"prefix":"10.1155","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-5888-3591","authenticated-orcid":false,"given":"Elahe","family":"Yaghmaei","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2516-0062","authenticated-orcid":false,"given":"Ahmad","family":"Najafi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7541-4214","authenticated-orcid":false,"given":"Reza","family":"Daneshvar Kakhki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,7,17]]},"reference":[{"key":"e_1_2_12_1_2","doi-asserted-by":"publisher","DOI":"10.1177\/1352458511406165"},{"key":"e_1_2_12_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ncl.2021.08.009"},{"key":"e_1_2_12_3_2","doi-asserted-by":"publisher","DOI":"10.3947\/ic.2016.48.4.334"},{"key":"e_1_2_12_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2015.16"},{"key":"e_1_2_12_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nrleng.2016.03.010"},{"key":"e_1_2_12_6_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1019132"},{"key":"e_1_2_12_7_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10112300"},{"key":"e_1_2_12_8_2","doi-asserted-by":"publisher","DOI":"10.1080\/00365540050165893"},{"key":"e_1_2_12_9_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.27652"},{"key":"e_1_2_12_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2021-241738"},{"key":"e_1_2_12_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cit356"},{"key":"e_1_2_12_12_2","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2017-221866"},{"key":"e_1_2_12_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.msard.2020.102643"},{"key":"e_1_2_12_14_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.18510"},{"key":"e_1_2_12_15_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.1046851"},{"key":"e_1_2_12_16_2","doi-asserted-by":"publisher","DOI":"10.37201\/req\/004.2023"},{"key":"e_1_2_12_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41394-018-0068-5"},{"key":"e_1_2_12_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/114.3.1181"},{"key":"e_1_2_12_19_2","doi-asserted-by":"publisher","DOI":"10.1177\/23259582221107196"}],"container-title":["Case Reports in Neurological Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2024\/9027198","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/2024\/9027198","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2024\/9027198","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T17:52:55Z","timestamp":1786384375000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2024\/9027198"}},"subtitle":[],"editor":[{"given":"Tapas Kumar","family":"Banerjee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":19,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["10.1155\/2024\/9027198"],"URL":"https:\/\/doi.org\/10.1155\/2024\/9027198","archive":["Portico"],"relation":{},"ISSN":["2090-6668","2090-6676"],"issn-type":[{"value":"2090-6668","type":"print"},{"value":"2090-6676","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"2023-10-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-13","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"9027198"}}