{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T15:26:26Z","timestamp":1753889186883,"version":"3.41.2"},"reference-count":17,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,8,20]],"date-time":"2024-08-20T00:00:00Z","timestamp":1724112000000},"content-version":"vor","delay-in-days":232,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Pediatrics"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p>Anti\u2010D antibody is the most common cause of hemolytic disease of the newborn (HDN). Other antigens have emerged, causing significant damage to the newborn. We report a case of a 31\u2010week dichorionic diamniotic twin born emergently to a mother with anti\u2010C and anti\u2010D antibodies who required multiple percutaneous umbilical cord blood sampling (PUBS) and transfusions. Extensive resuscitation at birth was required due to severe anemia, hypovolemia, and prematurity. Ensuing liver damage occurred with subsequent profound coagulopathy, transaminitis, and direct hyperbilirubinemia that required significant support. This patient developed several unique findings including the inability to monitor oxygen saturations due to dermal bilirubin deposits and staining of baby teeth. This case report highlights the importance of early identification of additional Rh antibodies due to concern for development of more severe forms of HDN.<\/jats:p>","DOI":"10.1155\/2024\/9180404","type":"journal-article","created":{"date-parts":[[2024,8,20]],"date-time":"2024-08-20T10:04:44Z","timestamp":1724148284000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Hepatic Failure and Hyperbilirubinemia Secondary to Hemolytic Disease of the Newborn"],"prefix":"10.1155","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-2554-1753","authenticated-orcid":false,"given":"Matthew","family":"Reinhardt","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9998-3948","authenticated-orcid":false,"given":"Marya L.","family":"Strand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dajana","family":"Sabic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,8,20]]},"reference":[{"key":"e_1_2_10_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-323-07447-6.00009-0"},{"key":"e_1_2_10_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-323-54458-0.00003-9"},{"key":"e_1_2_10_3_2","unstructured":"SarwarA.andCitla SridharD. Rh-Hemolytic Disease. ncbi.nlm.nih.gov 2022 https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK560488."},{"key":"e_1_2_10_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-814313-1.00005-8"},{"key":"e_1_2_10_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12288-012-0159-6"},{"key":"e_1_2_10_6_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0235807"},{"key":"e_1_2_10_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/s1089-3261(02)00050-8"},{"key":"e_1_2_10_8_2","first-page":"384","article-title":"Study of transfusion-related iron overload (trio) in pediatric patients with hematological malignancy and bone marrow failure syndromes","volume":"11","author":"Das S.","year":"2021","journal-title":"American Journal of Blood Research"},{"key":"e_1_2_10_9_2","doi-asserted-by":"publisher","DOI":"10.3238\/arztebl.m2021.0290"},{"key":"e_1_2_10_10_2","doi-asserted-by":"publisher","DOI":"10.1080\/17474086.2017.1331124"},{"key":"e_1_2_10_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41372-022-01345-1"},{"key":"e_1_2_10_12_2","doi-asserted-by":"publisher","DOI":"10.1159\/000362812"},{"key":"e_1_2_10_13_2","doi-asserted-by":"publisher","DOI":"10.1159\/000335333"},{"volume-title":"Blood Groups and Red Cell Antigens","year":"2005","author":"Dean L.","key":"e_1_2_10_14_2"},{"key":"e_1_2_10_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2011.09.024"},{"key":"e_1_2_10_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12288-016-0729-0"},{"key":"e_1_2_10_17_2","doi-asserted-by":"publisher","DOI":"10.1136\/fn.78.1.f62"}],"container-title":["Case Reports in Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2024\/9180404","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,20]],"date-time":"2024-08-20T10:04:50Z","timestamp":1724148290000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2024\/9180404"}},"subtitle":[],"editor":[{"given":"Vjekoslav","family":"Krzelj","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["10.1155\/2024\/9180404"],"URL":"https:\/\/doi.org\/10.1155\/2024\/9180404","archive":["Portico"],"relation":{},"ISSN":["2090-6803","2090-6811"],"issn-type":[{"type":"print","value":"2090-6803"},{"type":"electronic","value":"2090-6811"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"2024-01-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-13","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-20","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"9180404"}}