{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T14:36:43Z","timestamp":1753886203888,"version":"3.41.2"},"reference-count":14,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,8,27]],"date-time":"2024-08-27T00:00:00Z","timestamp":1724716800000},"content-version":"vor","delay-in-days":239,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Obstetrics and Gynecology"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> Metastatic vulvar choriocarcinoma, a rare ectopic gestational trophoblastic neoplasia (GTN), often presents a diagnostic challenge due to its mimicry of other conditions, particularly in resource\u2010limited settings. Its primary symptom is abnormal vaginal bleeding without a clear cause. Consequently, diagnosing and managing it poses difficulties for many low\u2010resource health facilities, as evidenced by the current case.<\/jats:p><jats:p><jats:bold>Case Presentation:<\/jats:bold> We present the case of a 25\u2010year\u2010old, P2+2+2L2, who had a large painless, bleeding vulva mass for nearly 5 months. This followed a spontaneous abortion the month prior. The mass gradually increased in size and was accompanied by fever, pus discharge, and weight loss. Despite being treated at multiple health facilities for a vulvar abscess, there was no improvement. A diagnosis was finally made at a tertiary facility where elevated quantitative serum beta\u2010human chorionic gonadotropin (hCG) (<jats:italic>\u03b2<\/jats:italic>\u2010hCG) was noted. Due to uncontrollable vulva bleeding, she was referred to another tertiary facility for emergency radiotherapy. Following stabilization, chemotherapy was administered using the EMA\u2010CO protocol.<\/jats:p><jats:p><jats:bold>Conclusion:<\/jats:bold> The report highlights the difficulty in diagnosing vulvar choriocarcinoma, underscoring the importance of a high index of suspicion. Clinical tests such as serum (<jats:italic>\u03b2<\/jats:italic>\u2010hCG) and imaging studies are crucial for diagnosis. In resource\u2010limited settings, a simple strip\u2010based urine pregnancy test with serial dilutions can be sufficient for diagnosing and managing vulvar choriocarcinoma.<\/jats:p>","DOI":"10.1155\/2024\/9918452","type":"journal-article","created":{"date-parts":[[2024,8,27]],"date-time":"2024-08-27T08:35:15Z","timestamp":1724747715000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Case of Metastatic Vulvar Choriocarcinoma Misdiagnosed as Vulvar Abscess: A Case Report"],"prefix":"10.1155","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7493-1623","authenticated-orcid":false,"given":"Alita","family":"Mrema","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prudence H.","family":"Kiwia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaban J.","family":"Shaban","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anwar Z.","family":"Mohamed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Latifa Rajab","family":"Abdallah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-3602-0543","authenticated-orcid":false,"given":"Rajabu","family":"Kiaratu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Mahoyogo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7325-1167","authenticated-orcid":false,"given":"Agapiti","family":"Chuwa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1729-9523","authenticated-orcid":false,"given":"David H.","family":"Mvunta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,8,27]]},"reference":[{"key":"e_1_2_11_1_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.13877"},{"key":"e_1_2_11_2_2","doi-asserted-by":"publisher","DOI":"10.4314\/ahs.v20i1.12"},{"key":"e_1_2_11_3_2","doi-asserted-by":"publisher","DOI":"10.1080\/20742835.2019.1667627"},{"key":"e_1_2_11_4_2","doi-asserted-by":"publisher","DOI":"10.4236\/oalib.1109923"},{"key":"e_1_2_11_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/jog.13677"},{"key":"e_1_2_11_6_2","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2019.01262"},{"key":"e_1_2_11_7_2","doi-asserted-by":"publisher","DOI":"10.4103\/njcp.njcp_625_19"},{"key":"e_1_2_11_8_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12957-020-02021-4"},{"key":"e_1_2_11_9_2","doi-asserted-by":"publisher","DOI":"10.17795\/ijcp-4389"},{"key":"e_1_2_11_10_2","doi-asserted-by":"publisher","DOI":"10.29328\/journal.cjog.1001101"},{"key":"e_1_2_11_11_2","doi-asserted-by":"publisher","DOI":"10.5603\/GP.a2018.0120"},{"key":"e_1_2_11_12_2","doi-asserted-by":"publisher","DOI":"10.1080\/14737140.2022.2038566"},{"key":"e_1_2_11_13_2","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15194817"},{"key":"e_1_2_11_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000000860"}],"container-title":["Case Reports in Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2024\/9918452","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,27]],"date-time":"2024-08-27T08:35:18Z","timestamp":1724747718000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2024\/9918452"}},"subtitle":[],"editor":[{"given":"Daniel","family":"Martin","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["10.1155\/2024\/9918452"],"URL":"https:\/\/doi.org\/10.1155\/2024\/9918452","archive":["Portico"],"relation":{},"ISSN":["2090-6684","2090-6692"],"issn-type":[{"type":"print","value":"2090-6684"},{"type":"electronic","value":"2090-6692"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"2024-06-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-27","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"9918452"}}