{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T22:25:52Z","timestamp":1771885552842,"version":"3.50.1"},"reference-count":12,"publisher":"Wiley","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology Research and Practice"],"published-print":{"date-parts":[[2024,6,1]]},"abstract":"<jats:p>Background. Granulomatous dermatoses, particularly on facial skin, pose a diagnostic challenge, as similar histologic patterns can be produced by different causes. Aim. To evaluate the correlation between clinical suspicion and histopathological findings in various facial granulomatous dermatoses. Materials and Methods. This retrospective, cross-sectional study included all patients with the histopathological diagnosis of facial granulomatous dermatoses from the years 2016 to 2021 in an academic hospital. Demographic, clinical, and histopathologic features were reviewed and analyzed. Results. In this study, 150 histopathological records with the diagnosis of facial granulomatous dermatoses from the years 2016 to 2021 were reviewed. The most common clinical diagnosis was rosacea 34 (23.6%), followed by sarcoidosis 27 (18.8%), leishmaniasis 15 (10.4%), and granulomatous rosacea 10 (6.9%). The frequency of clinical diagnosis of rosacea (70.6), sarcoidosis (66.7), foreign body G (62.5), TB (75), pseudolymphoma (75), acne agminata (66.7), and granulomatous rosacea (70) in female patients was higher than that in males (<jats:inline-formula><a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><a:mi>P<\/a:mi><\/a:math><\/jats:inline-formula> value\u2009=\u20090.03). The effect of age on the type of both clinical and histopathological diagnosis was statistically significant (<jats:inline-formula><c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><c:mi>P<\/c:mi><\/c:math><\/jats:inline-formula> value\u2009=\u20090.0001 and 0.004, respectively). Conclusion. Our study contributed significantly to the understanding of the clinicopathological aspects of facial granulomatous dermatoses and advocated for a multidisciplinary approach to the diagnosis and management of these complex skin conditions.<\/jats:p>","DOI":"10.1155\/2024\/9946828","type":"journal-article","created":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T14:35:08Z","timestamp":1717252508000},"page":"1-6","source":"Crossref","is-referenced-by-count":1,"title":["Clinicopathological Spectrum of Facial Granulomatous Dermatoses: Evidence from a 5-Year Study in Iran"],"prefix":"10.1155","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7077-1458","authenticated-orcid":true,"given":"Zeinab","family":"Aryanian","sequence":"first","affiliation":[{"name":"Autoimmune Bullous Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran"},{"name":"Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran"},{"name":"Department of Dermatology, Babol University of Medical Sciences, Babol, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8586-2432","authenticated-orcid":true,"given":"Mahshid","family":"Ansari","sequence":"additional","affiliation":[{"name":"Autoimmune Bullous Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran"},{"name":"Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7527-9267","authenticated-orcid":true,"given":"Huda","family":"Fatima","sequence":"additional","affiliation":[{"name":"Autoimmune Bullous Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mona","family":"Homayouni","sequence":"additional","affiliation":[{"name":"Blizard Institute, Queen Mary University of London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1867-1609","authenticated-orcid":true,"given":"Azadeh","family":"Khayyat","sequence":"additional","affiliation":[{"name":"Pathology Department of Medical College of Wisconsin, Milwaukee, WI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5753-8288","authenticated-orcid":true,"given":"Alireza","family":"Ghanadan","sequence":"additional","affiliation":[{"name":"Department of Dermatopathology, Razi Hospital, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3531-2907","authenticated-orcid":true,"given":"Parvaneh","family":"Hatami","sequence":"additional","affiliation":[{"name":"Autoimmune Bullous Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.45391"},{"key":"2","article-title":"Lupus miliaris disseminatus faciei. 2024 jan 10","volume-title":"StatPearls [Internet]. Treasure Island (FL): StatPearls Ublishing","author":"N. Slater","year":"2024"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.4103\/idoj.IDOJ_693_20"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.5826\/dpc.1304S1a297S"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.4103\/ijpm.ijpm_358_21"},{"issue":"2","key":"6","first-page":"22","article-title":"Severe granulomatous rosacea with cutaneous lupus erythematosus","volume":"14","author":"R. 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