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This study was performed to establish MDA, ApoB, and OxLDL levels in systemic lupus erythematosus (SLE) patients. Electronic databases were searched for the included articles up to 27th February 2023. The meta\u2010analysis included 48 articles with 2358 SLE patients and 2126 healthy controls considered for MDA, ApoB, and OxLDL levels. There were significantly higher MDA, ApoB, and OxLDL levels in SLE patients than those in the control groups. Subgroup analysis indicated that European\/American SLE patients and patients of both ages &lt;36 and \u226536 exhibited higher MDA, ApoB, and OxLDL levels. Arab and Asian SLE patients had higher ApoB and MDA\/OxLDL levels. African SLE patients recorded higher OxLDL levels than the control groups. SLE patients with a body mass index (BMI) of \u226523 and a disease duration of &lt;10 recorded significantly higher MDA, ApoB, and OxLDL levels. Patients with systemic lupus erythematosus disease activity index (SLEDAI) \u22658 of SLE had higher MDA and ApoB levels, whereas SLE patients with SLEDAI &lt;8 showed significantly higher ApoB levels. Patients with BMI &lt;23 of SLE had higher MDA and OxLDL levels. This study established significantly higher MDA, ApoB, and OxLDL levels in SLE patients, suggesting a possible role of MDA, ApoB, and OxLDL in the disease.<\/jats:p>","DOI":"10.1155\/2024\/9948612","type":"journal-article","created":{"date-parts":[[2024,7,20]],"date-time":"2024-07-20T09:49:48Z","timestamp":1721468988000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Plasma\/Serum Oxidant Parameters in Systemic Lupus Erythematosus Patients: A Systematic Review and Meta\u2010Analysis"],"prefix":"10.1155","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9056-551X","authenticated-orcid":false,"given":"Napoleon Bellua","family":"Sam","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Tabiri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ebenezer","family":"Amofa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,7,20]]},"reference":[{"key":"e_1_2_9_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0889-857x(21)00944-3"},{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.1079\/bjn2000239"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.53.1.51"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/00001648-200007000-00007"},{"key":"e_1_2_9_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.56.5.323"},{"key":"e_1_2_9_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0021-9258(18)90863-x"},{"key":"e_1_2_9_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0021-9258(18)61395-x"},{"key":"e_1_2_9_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0006-291x(03)01222-1"},{"key":"e_1_2_9_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/0891-5849(95)93872-4"},{"key":"e_1_2_9_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2008.04.013"},{"key":"e_1_2_9_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2013.03.013"},{"key":"e_1_2_9_12_2","doi-asserted-by":"publisher","DOI":"10.1080\/03009740701772465"},{"key":"e_1_2_9_13_2","doi-asserted-by":"publisher","DOI":"10.2217\/bmm-2019-0034"},{"key":"e_1_2_9_14_2","doi-asserted-by":"publisher","DOI":"10.1080\/08916930701574331"},{"key":"e_1_2_9_15_2","doi-asserted-by":"publisher","DOI":"10.1056\/nejm198904063201407"},{"key":"e_1_2_9_16_2","doi-asserted-by":"publisher","DOI":"10.1096\/fj.01-0273rev"},{"key":"e_1_2_9_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/136.3.765s"},{"key":"e_1_2_9_18_2","doi-asserted-by":"publisher","DOI":"10.1161\/hc4101.097518"},{"key":"e_1_2_9_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.20780"},{"key":"e_1_2_9_20_2","unstructured":"Apolipoprotein B from human plasma 2018 https:\/\/www.sigmaaldrich.com\/catalog\/product\/sigma\/a5353?lang=en&region=US."},{"key":"e_1_2_9_21_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12944-017-0476-8"},{"key":"e_1_2_9_22_2","doi-asserted-by":"publisher","DOI":"10.3892\/br.2015.544"},{"key":"e_1_2_9_23_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-006-0233-1"},{"key":"e_1_2_9_24_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-003-0358-4"},{"key":"e_1_2_9_25_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.20392"},{"key":"e_1_2_9_26_2","first-page":"23","article-title":"Insulin resistance is related with oxidative stress in systemic lupus erythematosus","volume":"9","author":"Koca S. 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