{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T17:31:25Z","timestamp":1760981485799,"version":"3.41.2"},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,9,5]],"date-time":"2006-09-05T00:00:00Z","timestamp":1157414400000},"content-version":"vor","delay-in-days":247,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["03\/10105-2","142616\/2005-2"],"award-info":[{"award-number":["03\/10105-2","142616\/2005-2"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["03\/10105-2","142616\/2005-2"],"award-info":[{"award-number":["03\/10105-2","142616\/2005-2"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Biomedical Imaging"],"published-print":{"date-parts":[[2006,1]]},"abstract":"<jats:p>Recent advances in neuroimaging techniques have provided precise spatial localization\nof brain activation applied in several neuroscience subareas. The development of functional\nmagnetic resonance imaging (fMRI), based on the BOLD signal, is one of the most popular\ntechniques related to the detection of neuronal activation. However, understanding the\ninteractions between several neuronal modules is also an important task, providing a better\ncomprehension about brain dynamics. Nevertheless, most connectivity studies in fMRI are based\non a simple correlation analysis, which is only an association measure and does not provide the\ndirection of information flow between brain areas. Other proposed methods like structural\nequation modeling (SEM) seem to be attractive alternatives. However, this approach assumes\nprior information about the causality direction and stationarity conditions, which may not be\nsatisfied in fMRI experiments. Generally, the fMRI experiments are related to an activation task;\nhence, the stimulus conditions should also be included in the model. In this paper, we suggest an intervention analysis, which includes stimulus condition, allowing a nonstationary modeling. Furthermore, an illustrative application to real fMRI\ndataset from a simple motor task is presented.<\/jats:p>","DOI":"10.1155\/ijbi\/2006\/27483","type":"journal-article","created":{"date-parts":[[2006,9,13]],"date-time":"2006-09-13T08:02:02Z","timestamp":1158134522000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Intervention Models in Functional Connectivity Identification Applied to fMRI"],"prefix":"10.1155","volume":"2006","author":[{"given":"Jo\u00e3o Ricardo","family":"Sato","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel Yasumasa","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ellison Fernando","family":"Cardoso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria da Gra\u00e7a Morais","family":"Martin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edson","family":"Amaro J\u00fanior","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro Alberto","family":"Morettin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,9,5]]},"reference":[{"key":"e_1_2_1_1_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910140108"},{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/7.8.768"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910340409"},{"volume-title":"Human Brain Function","year":"2003","author":"Frackowiak R. 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